Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David Schibli"'
Autor:
Sarah A. Michaud, Helena Pětrošová, Nicholas J. Sinclair, Andrea L. Kinnear, Angela M. Jackson, Jamie C. McGuire, Darryl B. Hardie, Pallab Bhowmick, Milan Ganguly, Ann M. Flenniken, Lauryl M. J. Nutter, Colin McKerlie, Derek Smith, Yassene Mohammed, David Schibli, Albert Sickmann, Christoph H. Borchers
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Mouse is the mammalian model of choice to study human health and disease due to its size, ease of breeding and the natural occurrence of conditions mimicking human pathology. Here we design and validate multiple reaction monitoring mass spec
Externí odkaz:
https://doaj.org/article/2609ea2007ea4af7ba418d2b5f7ec603
Autor:
Jason R. Bush, Jun Han, Edward C. Deehan, Scott V. Harding, Madhura Maiya, Joshua Baisley, David Schibli, David R. Goodlett
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105740- (2023)
Histamine from our diet or gut microbes can trigger gastrointestinal disturbances, and resistant potato starch (RPS) has previously been shown to alleviate these symptoms while increasing levels of health-associated bacteria such as Akkermansia throu
Externí odkaz:
https://doaj.org/article/f3f8813ef36b4637b228547a9c9501a1
Autor:
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
Abstract We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our
Externí odkaz:
https://doaj.org/article/72bd932c9079468a9baf2be34f40d25f
Autor:
Victor Buzon, Ganesh Natrajan, David Schibli, Felix Campelo, Michael M Kozlov, Winfried Weissenhorn
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000880 (2010)
The HIV-1 envelope glycoprotein (Env) composed of the receptor binding domain gp120 and the fusion protein subunit gp41 catalyzes virus entry and is a major target for therapeutic intervention and for neutralizing antibodies. Env interactions with ce
Externí odkaz:
https://doaj.org/article/d642bbbc55a1477d878fab8a83d1108e
Autor:
Shahla Shojaei, João Basso, Meitham Amereh, Javad Alizadeh, Tania Dehesh, Simone De Silva Rosa, Courtney Clark, Misha Hassan, Mateuz Tomczyk, Laura Cole, Grant Hatch, Vern Dolinsky, Chris Pasco, David Schibli, Sanjiv Dhingra, Abhay Srivastava, Amir Ravandi, Rui Vitorino, Saeid Ghavami, Mohsen Akbari
Chemoresistance is a major clinical challenge in the management of glioblastoma (GBM) Temozolomide (TMZ) is the chemotherapeutic drug of choice for GBM; however, the therapeutic effect of TMZ is limited due to the development of resistance. Recapitul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd0c65d247c7fabb35433de79340dda4
https://doi.org/10.1101/2022.10.29.514383
https://doi.org/10.1101/2022.10.29.514383
Autor:
Sarah A. Michaud, Angela M. Jackson, Christoph H. Borchers, Derek Smith, Ann M Flenniken, Nicholas J. Sinclair, Colin McKerlie, Lauryl M. J. Nutter, Milan Ganguly, David Schibli, Helena Pětrošová, Jamie C McGuire
Publikováno v:
Journal of Proteome Research. 20:305-316
We investigated the effect of homogenization strategy and protein precipitation on downstream protein quantitation using multiple reaction monitoring mass spectrometry (MRM-MS). Our objective was to develop a workflow capable of processing disparate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cd9f8bbb4812ed4cdd8215164df6f6
https://doi.org/10.1021/acs.jproteome.0c00399
https://doi.org/10.1021/acs.jproteome.0c00399
Publikováno v:
RSC Advances. 10:34261-34265
Cucurbit[7]uril was used to form non-covalent complexes with low-molecular-weight quaternary-ammonium compounds for their indirect analysis by MALDI-MS. By shifting the ion signals to a higher and interference-free mass region, the distributions of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5988b9bcda0120a70c79289ed8f1d05
https://doi.org/10.1039/d0ra04604c
https://doi.org/10.1039/d0ra04604c
Autor:
Karl Smith-Byrne, Agustin Cerani, Florence Guida, Sirui Zhou, Antonio Agudo, Krasimira Aleksandrova, Aurelio Barricarte, Miguel Rodríguez Barranco, Christoph H. Bochers, Inger Torhild Gram, Jun Han, Christopher I. Amos, Rayjean J. Hung, Kjell Grankvist, Therese Haugdhal Nøst, Liher Imaz, María Dolores Chirlaque-López, Mikael Johansson, Rudolf Kaaks, Tilman Kühn, Richard M. Martin, James D. McKay, Valeria Pala, Hilary A. Robbins, Torkjel M. Sandanger, David Schibli, Matthias B. Schulze, Ruth C. Travis, Paolo Vineis, Elisabete Weiderpass, Paul Brennan, Mattias Johansson, J. Brent Richards
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Smith Byrne, K, Martin, R M, Richards, B & Johansson, M 2022, ' Circulating Isovalerylcarnitine and Lung Cancer Risk : Evidence from Mendelian Randomization and Pre-Diagnostic Blood Measurements ', Cancer Epidemiology, Biomarkers and Prevention, vol. 31, no. 10, EPI-21-1033, pp. 1966-1974 . https://doi.org/10.1158/1055-9965.EPI-21-1033
Smith Byrne, K, Martin, R M, Richards, B & Johansson, M 2022, ' Circulating Isovalerylcarnitine and Lung Cancer Risk : Evidence from Mendelian Randomization and Pre-Diagnostic Blood Measurements ', Cancer Epidemiology, Biomarkers and Prevention, vol. 31, no. 10, EPI-21-1033, pp. 1966-1974 . https://doi.org/10.1158/1055-9965.EPI-21-1033
Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies. Materials and Methods: We used Mendelian randomization (MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e9faeb07bef8d811adec87c3e5f0f4
https://hdl.handle.net/10037/27964
https://hdl.handle.net/10037/27964
Autor:
Hibret A. Adissu, Sarah A. Michaud, Helena Pětrošová, Christoph H. Borchers, Juncong Yang, Colin McKerlie, Milan Ganguly, Yassene Mohammed, Ann M Flenniken, David Schibli, Lauryl M. J. Nutter, Kevin C K Lloyd
Publikováno v:
NPJ Systems Biology and Applications
npj Systems Biology and Applications, 7(1). NATURE RESEARCH
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
NPJ systems biology and applications, vol 7, iss 1
npj Systems Biology and Applications, 7(1). NATURE RESEARCH
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
NPJ systems biology and applications, vol 7, iss 1
We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7762eba7e19dd55b25143a5c516d0896
https://pubmed.ncbi.nlm.nih.gov/34050187
https://pubmed.ncbi.nlm.nih.gov/34050187
Publikováno v:
Biochemistry Publications
The gene sap/shd1a, which encodes a 128-residue SH2 domain protein, is frequently deleted or mutated in the X-linked lymphoproliferative syndrome (XLP). The SAP SH2 domain differs from others in the same class in that it is not only capable of bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b843977f1fec7b4472d6510d3e0fbd
https://doi.org/10.1016/j.cellsig.2008.09.014
https://doi.org/10.1016/j.cellsig.2008.09.014