Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David Schafflick"'
Autor:
Carolin Beuker, David Schafflick, Jan-Kolja Strecker, Michael Heming, Xiaolin Li, Jolien Wolbert, Antje Schmidt-Pogoda, Christian Thomas, Tanja Kuhlmann, Irene Aranda-Pardos, Noelia A-Gonzalez, Praveen Ashok Kumar, Yves Werner, Ertugrul Kilic, Dirk M. Hermann, Heinz Wiendl, Ralf Stumm, Gerd Meyer zu Hörste, Jens Minnerup
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
How ischaemic stroke affects the brain borders is not fully understood. Here the authors show that a stroke-associated myeloid cell population occurs exclusively in brain parenchyma that shares features with neurodegenerative microglia and blockade o
Externí odkaz:
https://doaj.org/article/19382b9ff80a421facdf68942549d672
Autor:
David Schafflick, Chenling A. Xu, Maike Hartlehnert, Michael Cole, Andreas Schulte-Mecklenbeck, Tobias Lautwein, Jolien Wolbert, Michael Heming, Sven G. Meuth, Tanja Kuhlmann, Catharina C. Gross, Heinz Wiendl, Nir Yosef, Gerd Meyer zu Horste
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here the authors provide a single-cell characterization of cerebrospinal fluid and blood of newly diagnosed multiple sclerosis (MS) patients, revealing altered composition of lymphocyte and monocyte subsets, validated by other methods including the i
Externí odkaz:
https://doaj.org/article/2757449eb302442da1fbdc95f72a25a4
Autor:
Maren Kasper, Michael Heming, David Schafflick, Xiaolin Li, Tobias Lautwein, Melissa Meyer zu Horste, Dirk Bauer, Karoline Walscheid, Heinz Wiendl, Karin Loser, Arnd Heiligenhaus, Gerd Meyer zu Hörste
Publikováno v:
eLife, Vol 10 (2021)
Uveitis describes a heterogeneous group of inflammatory eye diseases characterized by infiltration of leukocytes into the uveal tissues. Uveitis associated with the HLA haplotype B27 (HLA-B27) is a common subtype of uveitis and a prototypical ocular
Externí odkaz:
https://doaj.org/article/757c955af77f4ad394c56bea4c8ae6a8
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-17 (2017)
Abstract Inflammatory neuropathies are rare autoimmune-mediated disorders affecting the peripheral nervous system. Considerable progress has recently been made in understanding pathomechanisms of these disorders which will be essential for developing
Externí odkaz:
https://doaj.org/article/41eadadf20964875b4fee1c0ad3429cd
Autor:
Claudia Janoschka, Maren Lindner, Nils Koppers, Laura Starost, Marie Liebmann, Melanie Eschborn, Tilman Schneider-Hohendorf, Farina Windener, David Schafflick, Ann-Katrin Fleck, Kathrin Koch, Marie Deffner, Anna-Sophie Schwarze, Andreas Schulte-Mecklenbeck, Imke Metz, Sven G. Meuth, Catharina C. Gross, Gerd Meyer zu Hörste, Nicholas Schwab, Tanja Kuhlmann, Heinz Wiendl, Monika Stoll, Luisa Klotz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(1)
After natalizumab (NAT) cessation, some multiple sclerosis (MS) patients experience a severe disease rebound. The rebound pathophysiology is still unclear; however, it has been linked to interleukin-17-producing T-helper (Th17) cells. We demonstrate
Autor:
Arnd Heiligenhaus, Xiaolin Li, Karoline Walscheid, Michael Heming, Dirk Bauer, Maren Kasper, Tobias Lautwein, Heinz Wiendl, Melissa Meyer zu Horste, Gerd Meyer zu Hörste, Karin Loser, David Schafflick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d495bc712d2642b6173c78478791dbd
https://doi.org/10.7554/elife.67396.sa2
https://doi.org/10.7554/elife.67396.sa2
Autor:
Karoline Walscheid, M. Meyer zu Horste, Heinz Wiendl, Tobias Lautwein, G. Meyer zu Hörste, Dirk Bauer, Karin Loser, David Schafflick, Michael Heming, Arnd Heiligenhaus, Maren Kasper, Xiaolin Li
Uveitis describes a heterogeneous group of inflammatory eye diseases characterized by infiltration of leukocytes into the uveal tissues. HLA-B27-associated uveitis is a common subtype of uveitis and a prototypical ocular autoimmune disease. Local imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0467d1038b20f5b728b073920d63fad
https://doi.org/10.1101/2021.02.16.431370
https://doi.org/10.1101/2021.02.16.431370
Autor:
Gerd Meyer zu Hörste, Michael Heming, Karoline Walscheid, Melissa Meyer zu Horste, Maren Kasper, Heinz Wiendl, Karin Loser, David Schafflick, Arnd Heiligenhaus, Tobias Lautwein, Dirk Bauer, Xiaolin Li
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Uveitis describes a heterogeneous group of inflammatory eye diseases characterized by infiltration of leukocytes into the uveal tissues. Uveitis associated with the HLA haplotype B27 (HLA-B27) is a common subtype of uveitis and a prototypical ocular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c76bf7a2b48f96ec4f1611a0c01645
https://www.ncbi.nlm.nih.gov/pubmed/34783307
https://www.ncbi.nlm.nih.gov/pubmed/34783307
Autor:
Carolin, Beuker, David, Schafflick, Jan-Kolja, Strecker, Michael, Heming, Xiaolin, Li, Jolien, Wolbert, Antje, Schmidt-Pogoda, Christian, Thomas, Tanja, Kuhlmann, Irene, Aranda-Pardos, Noelia, A-Gonzalez, Praveen Ashok, Kumar, Yves, Werner, Ertugrul, Kilic, Dirk M, Hermann, Heinz, Wiendl, Ralf, Stumm, Gerd, Meyer Zu Hörste, Jens, Minnerup
Publikováno v:
Nature communications. 13(1)
Inflammation triggers secondary brain damage after stroke. The meninges and other CNS border compartments serve as invasion sites for leukocyte influx into the brain thus promoting tissue damage after stroke. However, the post-ischemic immune respons
Autor:
Thomas Seidenbecher, Sandra Martín-Salamanca, Jan-Kolja Strecker, Xiaolin Li, Jens Minnerup, Arthur Liesz, Michael Heming, Christian Thomas, Sven G. Meuth, Maike Hartlehnert, Anna-Lena Börsch, I-Na Lu, Alessio Ricci, Andrés Hidalgo, David Schafflick, Mathias Pawlak, Jolien Wolbert, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
Nature neuroscience. 24(9)
The CNS is ensheathed by the meninges and cerebrospinal fluid, and recent findings suggest that these CNS-associated border tissues have complex immunological functions. Unlike myeloid lineage cells, lymphocytes in border compartments have yet to be