Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David Santiago-Algarra"'
Autor:
David Santiago-Algarra, Charbel Souaid, Himanshu Singh, Lan T. M. Dao, Saadat Hussain, Alejandra Medina-Rivera, Lucia Ramirez-Navarro, Jaime A. Castro-Mondragon, Nori Sadouni, Guillaume Charbonnier, Salvatore Spicuglia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Some promoters, termed Epromoters, can display enhancer activity and regulate distal genes in their endogenous context. Here the authors report the broad involvement of Epromoters in the coordinated activation of interferon (IFN) response. They show
Externí odkaz:
https://doaj.org/article/2a838a6dac1c4a42aac0c04facbcf0f8
Autor:
Jaafar Alomairi, Anne M Molitor, Nori Sadouni, Saadat Hussain, Magali Torres, Wiam Saadi, Lan T M Dao, Guillaume Charbonnier, David Santiago-Algarra, Jean Christophe Andrau, Denis Puthier, Tom Sexton, Salvatore Spicuglia
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233191 (2020)
The Ikzf1 locus encodes the lymphoid specific transcription factor Ikaros, which plays an essential role in both T and B cell differentiation, while deregulation or mutation of IKZF1/Ikzf1 is involved in leukemia. Tissue-specific and cell identity ge
Externí odkaz:
https://doaj.org/article/c6babbb5c5134b56b0768caedee2e919
Publikováno v:
F1000Research, Vol 6 (2017)
The regulation of gene transcription in higher eukaryotes is accomplished through the involvement of transcription start site (TSS)-proximal (promoters) and -distal (enhancers) regulatory elements. It is now well acknowledged that enhancer elements p
Externí odkaz:
https://doaj.org/article/29008be422174d90b32aabbaf3bd0e75
Publikováno v:
Biologie Aujourd'hui. 211:271-280
La regulation de la transcription des genes chez les eucaryotes superieurs implique l’action d’elements regulateurs proximaux (promoteurs) ou distaux (amplificateurs ou enhancers ) du site d’initiation de la transcription (Transcription Start S
Publikováno v:
Trends in Biochemical Sciences
Trends in Biochemical Sciences, Elsevier, 2018, 43 (6), pp.452-468. 〈10.1016/j.tibs.2018.03.004〉
Trends in Biochemical Sciences, Elsevier, 2018, 43 (6), pp.452-468. ⟨10.1016/j.tibs.2018.03.004⟩
Trends in Biochemical Sciences, Elsevier, 2018, 43 (6), pp.452-468. 〈10.1016/j.tibs.2018.03.004〉
Trends in Biochemical Sciences, Elsevier, 2018, 43 (6), pp.452-468. ⟨10.1016/j.tibs.2018.03.004⟩
Gene expression in higher eukaryotes is precisely regulated in time and space through the interplay between promoters and gene-distal regulatory regions, known as enhancers. The original definition of enhancers implies the ability to activate gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c273f32892c2d3ac7fb8f91e2f4f08f5
https://hal-amu.archives-ouvertes.fr/hal-01808594
https://hal-amu.archives-ouvertes.fr/hal-01808594
Publikováno v:
Biologie aujourd'hui. 211(4)
Gene expression in higher eukaryotes is regulated through the involvement of transcription start site (TSS)-proximal (promoters) and -distal (enhancers) regulatory elements. Enhancer elements play an essential role during development and cell differe
Autor:
M. Gomez-Moreno, Martin Zapata-Zúñiga, Noe Macias-Segura, Cesar Ramos-Remus, Jose Dionisio Castillo-Ortiz, Leonor Enciso-Moreno, A.L. Alemán-Navarro, Roberto González-Amaro, Julio Enrique Castañeda-Delgado, Yadira Bastián, José Antonio Enciso-Moreno, David Santiago-Algarra, C. A. Saucedo-Toral, E. Jaime-Sánchez, Edgar E. Lara-Ramírez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194205 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194205 (2018)
Background Little is known regarding the mechanisms underlying the loss of tolerance in the early and preclinical stages of autoimmune diseases. The aim of this work was to identify the transcriptional profile and signaling pathways associated to non
Autor:
Jose Dionisio Castillo-Ortiz, José Antonio Enciso-Moreno, Hilda Susana Nava-Ramírez, Cesar Ramos-Remus, Julio Enrique Castañeda-Delgado, Noe Macias-Segura, David Santiago-Algarra, Yadira Bastián, Martín Zapata-Zuñiga, Maria Fernanda Romo-García
Publikováno v:
International journal of immunogenetics. 46(2)
Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by chronic and symmetrical inflammation of synovial tissue with subsequent joint destruction. SUMO1 is an important regulator of apoptosis through non-canonical mechanism in sy
Publikováno v:
F1000Research
F1000Research, Faculty of 1000, 2017, 6, pp.939. ⟨10.12688/f1000research.11581.1⟩
F1000Research, 2017, 6, pp.939. ⟨10.12688/f1000research.11581.1⟩
F1000Research, Faculty of 1000, 2017, 6, pp.939. ⟨10.12688/f1000research.11581.1⟩
F1000Research, 2017, 6, pp.939. ⟨10.12688/f1000research.11581.1⟩
The regulation of gene transcription in higher eukaryotes is accomplished through the involvement of transcription start site (TSS)-proximal (promoters) and -distal (enhancers) regulatory elements. It is now well acknowledged that enhancer elements p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762be8c80ca914d4934eb631d18c469e
https://hal-amu.archives-ouvertes.fr/hal-01612096
https://hal-amu.archives-ouvertes.fr/hal-01612096
Autor:
Jose Dionisio Castillo-Ortiz, Diana Olguín-Calderón, Julio Enrique Castañeda-Delgado, José Antonio Enciso-Moreno, Leonor Enciso-Moreno, David Santiago-Algarra, Yadira Bastian-Hernandez, Ana L. Alemán-Navarro, P. Martínez-Tejada, Noe Macias-Segura, Leendert A. Trouw, Yolanda García de Lira, Cesar Ramos-Remus
Publikováno v:
Frontiers in Immunology
Background Rheumatoid arthritis (RA) is an inflammatory debilitating disease that affects the joints in the early and productive phases of an individual’s life. Several cytokines have been linked to the disease pathogenesis and are known to contrib