Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David Sansom"'
Autor:
Evaggelia Liaskou, Louisa Jeffery, Dimitrios Chanouzas, Blagoje Soskic, Michael F. Seldin, Lorraine Harper, David Sansom, Gideon M. Hirschfield
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The CD28 locus is associated with susceptibility to a variety of autoimmune and immune-mediated inflammatory diseases including primary sclerosing cholangitis (PSC). Previously, we linked the CD28 pathway in PSC disease pathology and found t
Externí odkaz:
https://doaj.org/article/e5a9b051286947d2a6faeaf9453b110f
Autor:
David Sansom, Stuart Cumella
Publikováno v:
Mental Handicap Research. 7:257-272
There is no consistent pattern of services in England for people with a learning disability who offend or have severe anti-social behaviours (‘mental impairment’). In one English health region, the mental impairment service comprises two resident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e28b67b9fe0febe31e5479d3030bff4
https://doi.org/10.1111/j.1468-3148.1994.tb00130.x
https://doi.org/10.1111/j.1468-3148.1994.tb00130.x
Autor:
Stuart Cumella, David Sansom
Publikováno v:
The Journal of Forensic Psychiatry. 6:267-276
Information was collected about 100 successive admissions to a regional secure unit for people with a learning disability (mental handicap). Most of the patients were males under the age of 30, with a mild or borderline learning disability. A majorit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e20d0b647eee48e5f91cac0eede2557a
https://doi.org/10.1080/09585189508409894
https://doi.org/10.1080/09585189508409894
Autor:
Ag, Wingren, Dahlenborg K, Björklund M, Hedlund G, Kalland T, Ho, Sjögren, Ljungdahl A, Olsson T, Hp, Ekre, David Sansom
Publikováno v:
Europe PubMed Central
Cooperation between monocytes and T lymphocytes is essential for several aspects of immunologic activation. We have utilized PHA and IL-2-activated human T cells to characterize the role of monocytes in the regulation of T cell-derived IFN-gamma prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e553d650ef654d0ed30eb7236c5248
https://doi.org/10.4049/jimmunol.151.3.1328
https://doi.org/10.4049/jimmunol.151.3.1328
Autor:
Zoe Briggs, David Sansom
Publikováno v:
The Journal of Immunology. 190:121.13-121.13
Controlling T cell activation is important to prevent autoimmunity. Costimulatory molecules CD28 and CTLA-4 bind the same ligands (CD80 and CD86) but cause opposite outcomes: CD28 signalling enhances TCR signals whereas CTLA-4 inhibits T cell activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e139c073d2d35dfd123100e9fe9ec780
https://doi.org/10.4049/jimmunol.190.supp.121.13
https://doi.org/10.4049/jimmunol.190.supp.121.13
Autor:
David Sansom
Publikováno v:
Endocrine Abstracts. :1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da12466e725a35fad4d7caf366491a24
https://doi.org/10.1530/endoabs.31.s12.4
https://doi.org/10.1530/endoabs.31.s12.4
Publikováno v:
Europe PubMed Central
A major obstacle in understanding the signaling events that follow CD28 receptor ligation arises from the fact that CD28 acts as a costimulus to TCR engagement, making it difficult to assess the relative contribution of CD28 signals as distinct from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b3b5742ccd58118abdcfce06db48549c
https://pubmed.ncbi.nlm.nih.gov/8871623
https://pubmed.ncbi.nlm.nih.gov/8871623
Publikováno v:
Europe PubMed Central
The requirement for co-stimulation in T-cell activation has become firmly established, whilst the precise identity of the molecules involved remains uncertain. Some of the major co-stimulatory molecules include ICAM-1, LFA-3 and B7. We have investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fe7b5d84e88c336b2fe2dd51a798bbda
https://pubmed.ncbi.nlm.nih.gov/7505258
https://pubmed.ncbi.nlm.nih.gov/7505258
Publikováno v:
Europe PubMed Central
Thirty-two patients with the Felty syndrome, defined by the presence of rheumatoid arthritis, splenomegaly, and neutropenia, have been studied in comparison with 32 patients with rheumatoid arthritis matched for age, sex, and disease duration, and 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b072926e19b6757a72c437bed950ac6f
https://pubmed.ncbi.nlm.nih.gov/1969604
https://pubmed.ncbi.nlm.nih.gov/1969604
Autor:
David Sansom
Publikováno v:
Children's Literature in Education. 2:54-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4a9af15d4e3420491395e2621164830
https://doi.org/10.1007/bf01213231
https://doi.org/10.1007/bf01213231