Výsledky vyhledávání - "David Sankaran"

A simple method for culturing mouse vascular endothelium

Autor: Alyssa M. Krasinskas, David Sankaran, Alexander S. Krupnick, Wilson Y. Szeto, Daniel Kreisel, Bruce R. Rosengard, Kunjlata M. Amin, Sicco H. Popma

Publikováno v: Journal of Immunological Methods. 254:31-45

Vascular endothelium is an important site for a wide array of immunological processes such as inflammation, atherosclerosis and allograft rejection. Culture methods of mouse vascular endothelium would provide an important in vitro correlate to immuno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba73f36ab842b8cce43f48dbd39818e
https://doi.org/10.1016/s0022-1759(01)00371-4

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ASSOCIATION OF POLYMORPHISMS IN THE HUMAN INTERFERON -?? AND INTERLEUKIN-10 GENE WITH ACUTE AND CHRONIC KIDNEY TRANSPLANT OUTCOME

Autor: Vera Pravica, David Sankaran, Ian Roberts, Paul J. Sinnott, Ian V. Hutchinson, Argiris Asderakis, Robert W. G. Johnson, Phil Dyer

Publikováno v: Transplantation. 71:674-678

BACKGROUND Our group has previously described five different size alleles of an interferon (IFN)-gamma microsatellite. Analyzing this polymorphism, this study correlated high IFN-gamma production with a 12 CA repeat allele (allele 2). Further, our gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd5d98a8ccfd1f948d3ada57d725804
https://doi.org/10.1097/00007890-200103150-00018

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T Cell Effector Function and Anergy Avoidance Are Quantitatively Linked to Cell Division

Autor: Andrew D. Wells, Matthew C. Walsh, David Sankaran, Laurence A. Turka

Publikováno v: The Journal of Immunology. 165:2432-2443

We have shown previously that T cells activated by optimal TCR and CD28 ligation exhibit marked proliferative heterogeneity, and ∼40% of these activated cells fail entirely to participate in clonal expansion. To address how prior cell division infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701771ee630c09b1e599e51a09f9677b
https://doi.org/10.4049/jimmunol.165.5.2432

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Cytokine gene polymorphisms predict acute graft rejection following renal transplantation

Autor: Shazad Ashraf, Paul J. Sinnott, Colin D. Short, P.A. Dyer, Argiris Asderakis, I.A.N.S.D. Roberts, David Sankaran, Ian V. Hutchinson

Publikováno v: Kidney International. 56(1):281-288

Cytokine gene polymorphisms predict acute graft rejection following renal transplantation.BackgroundThe proinflammatory cytokine tumor necrosis factor-α (TNF-α) has been implicated in the pathogenesis of acute rejection, while animal models suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d749f3b27e0d26b9ebb66f100aab6fd

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Interaction of kunjin virus with octyl-d-glucoside extracted Vero cell plasma membrane

Autor: Lionel C. L. Lau, David Sankaran, Mah Lee Ng

Publikováno v: Journal of Virological Methods. 63:167-173

Initial experiments using whole cells have shown that there were specific and saturable interactions between kunjin (KUN) virus and receptor molecules on the Vero cell surfaces. Solubilisation of Vero cell plasma membranes with octyl-D-glucoside (OG)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d022bfc2d444793c703c77f788b816a
https://doi.org/10.1016/s0166-0934(96)02125-8

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Interleukin-2-mediated survival and proliferative signals are uncoupled in T lymphocytes that fail to divide after activation

Autor: Laurence A. Turka, David Sankaran, Andrew D. Wells, Daniel Kreisel

Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2(2)

T lymphocytes are heterogeneous with respect to their ability to proliferate following activation in vitro and in vivo. Approximately 30% of T lymphocytes fail to progress through the cell cycle, despite showing evidence of an activated state. The po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108823633ae907416aa9a1fbd95dadf2
https://pubmed.ncbi.nlm.nih.gov/12099513

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