Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David S.L. Kim"'
Autor:
Patrick Allaire, Jing He, John Mayer, Luke Moat, Peter Gerstenberger, Reynor Wilhorn, Sierra Strutz, David S.L. Kim, Chenjie Zeng, Nancy Cox, Jerry W. Shay, Joshua Denny, Lisa Bastarache, Scott Hebbring
Publikováno v:
HGG Advances, Vol 4, Iss 3, Pp 100201- (2023)
Summary: Many epidemiologic studies have identified important relationships between leukocyte telomere length (LTL) with genetics and health. Most of these studies have been significantly limited in scope by focusing predominantly on individual disea
Externí odkaz:
https://doaj.org/article/6d78ffb73da14b06ada708fe5fdd4135
Autor:
David S.L. Kim, Nallasivam Palanisamy, Jung H. Kim, Pankaj Vats, Saravana M. Dhanasekaran, Douglas R. Fullen, Xuhong Cao, Timothy D. Johnson, Rohit Mehra, Arul M. Chinnaiyan
Publikováno v:
Translational Oncology. 6:405-412
E26 transformation-specific (ETS) transcription factors are known to be involved in gene aberrations in various malignancies including prostate cancer; however, their role in melanoma oncogenesis has yet to be fully explored. We have completed a comp
Autor:
Pedram Pouryazdanparast, Linglei Ma, Limin Yu, Paul W. Harms, Douglas R. Fullen, David S.L. Kim
Publikováno v:
Modern Pathology. 23:1209-1214
Nodal, a potent embryonic morphogen in the transforming growth factor-beta family, is a proposed key regulator of melanoma tumorigenicity. However, there has been no systematic study of Nodal expression in melanocytic lesions. We investigated Nodal e
Autor:
Michael S. Khodadoust, Ferdinand Kappes, David S.L. Kim, David M. Markovitz, Arul M. Chinnaiyan, Maria S. Soengas, Monique Verhaegen, Juan C. Cigudosa, Erica Riveiro-Falkenbach
Publikováno v:
Cancer Research. 69:6405-6413
Gain of chromosome 6p is a consistent feature of advanced melanomas. However, the identity of putative oncogene(s) associated with this amplification has remained elusive. The chromatin remodeling factor DEK is an attractive candidate as it maps to 6
Autor:
Xiaohong Jin, J Swenson, Peter Kuffa, Peter C. Lucas, Dawn Kohrt, David S.L. Kim, Linda M. McAllister-Lucas, Katy Siu, Shufang Gu
Publikováno v:
Oncogene. 26:5643-5654
Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common extranodal lymphoid neoplasm. Chromosomal translocation t(11;18)(q21,q21) is found in 30% of gastric MALT lymphomas and is associated with a failure to respond to standard treatment
Autor:
David S.L. Kim, Clare E. Rogers, John B. Lowe, Peter L. Smith, Glennda Smithson, Jay T. Myers, E. Paul Scheidegger, Bronislawa Petryniak, Jonathon W. Homeister
Publikováno v:
The Journal of Experimental Medicine
To determine how the α(1,3)fucosyltransferases Fuc-TIV and Fuc-TVII, and the selectin ligands they control may contribute to the adaptive immune response, contact hypersensitivity (CHS) was characterized in mice deficient in either or both enzymes.
Autor:
Michael S. Khodadoust, Ferdinand Kappes, David S.L. Kim, David M. Markovitz, Limin Yu, Linglei Ma, Douglas R. Fullen
Publikováno v:
Human pathology. 42(7)
The diagnosis of malignant melanoma presents a clinical challenge and relies principally on histopathological evaluation. Previous studies have indicated that increased expression of the DEK oncogene, a chromatin-bound factor, could contribute to the
Autor:
David S.L. Kim, Mark Naftanel, Lili Zhao, Lori Lowe, Vernon K. Sondak, Christopher D. Lao, Dean E. Brenner, Stephen H. Olsen, Timothy D. Johnson
Publikováno v:
Journal of the American Academy of Dermatology. 64(6)
Autor:
Katy Siu, Tak W. Mak, Xiaohong Jin, Dawn Kohrt, Peter C. Lucas, Peter Kuffa, Shufang Gu, Gabriel Núñez, David S.L. Kim, Linda M. McAllister-Lucas, Jürgen Ruland
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(1)
Angiotensin II (Ang II) is a peptide hormone that, like many cytokines, acts as a proinflammatory agent and growth factor. After injury to the liver, the hormone assists in tissue repair by stimulating hepatocytes and hepatic stellate cells to synthe
Autor:
Tobenna Anens, Timothy M. Johnson, Paul W. Harms, Alexandra C. Hristov, David S.L. Kim, Douglas R. Fullen, Javed Siddiqui, Nallasivam Palanisamy, Michael J. Quist, Arul M. Chinnaiyan, Shannon Carskadon, Rohit Mehra
Publikováno v:
Human Pathology: Case Reports, Vol 1, Iss 2, Pp 21-28 (2014)
Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that promotes tumorigenesis by epigenetic repression of tumor suppressor genes. Although EZH2 is overexpressed in many malignancies, activating EZH2 mutations have been described predo