Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David S. Tsao"'
Autor:
Edward B. Samson, David S. Tsao, Jan Zimak, R. Tyler McLaughlin, Nicholaus J. Trenton, Emily M. Mace, Jordan S. Orange, Volker Schweikhard, Michael R. Diehl
Publikováno v:
Biology Open, Vol 6, Iss 6, Pp 785-799 (2017)
IQGAP1 is a large, multi-domain scaffold that helps orchestrate cell signaling and cytoskeletal mechanics by controlling interactions among a spectrum of receptors, signaling intermediates, and cytoskeletal proteins. While this coordination is known
Externí odkaz:
https://doaj.org/article/f292250d8fa2446fbe40ac69e66c7c58
Membrane and Actin Tethering Transitions Help IQGAP1 Coordinate GTPase and Lipid Messenger Signaling
Autor:
Emily M. Mace, Satya K. Bellamkonda, R. Tyler McLaughlin, Volker Schweikhard, Michael R. Diehl, Alexandra Rodzinski, Nicholaus J. Trenton, Jordan S. Orange, David S. Tsao
Publikováno v:
Biophys J
The coordination of lipid messenger signaling with cytoskeletal regulation is central to many organelle-specific regulatory processes. This coupling often depends on the function of multidomain scaffolds that orchestrate transient interactions among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb3892c5a58bb3badfb267b1bdbcd51
https://doi.org/10.1016/j.bpj.2019.12.023
https://doi.org/10.1016/j.bpj.2019.12.023
Autor:
David S. Tsao, Oguzhan Atay, Tim M. Townes, Spencer G. Kuper, Frederick D. Goldman, Brian P. Landry, Kevin M. Pawlik, Devon Chandler-Brown, Akila Subramaniam, Vivien A. Sheehan, Patrick P. Ye, Erik Westin, Jennifer Hoskovec, Brian Alford
BackgroundSickle cell disease (SCD) and beta thalassemia (β-thalassemia) are among the most common and severe genetically inherited disorders in the world. Although the maternal carrier status of these beta hemoglobinopathies is screened as a part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63b6f5d0404a4f1e30cbfb06e7240b0
https://doi.org/10.1101/2021.09.02.21262837
https://doi.org/10.1101/2021.09.02.21262837
There is currently an urgent unmet need to increase coronavirus disease 2019 (COVID-19) testing capability to effectively respond to the COVID-19 pandemic. However, the current shortage in RNA extraction reagents as well as limitations in qPCR protoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a323b7e5ec1d5261b1bad9095909322
Autor:
Samuel Greenberg, Amy B. Nguyen, Vivien A. Sheehan, Celeste K. Kanne, Oguzhan Atay, Rahul Shukla, Nelda Itzep, David S. Tsao, Brian P. Landry, Prem N. Arora, Rani Sharma, Sukrit Silas
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Next-generation DNA sequencing is currently limited by an inability to accurately count the number of input DNA molecules. Molecular counting is particularly needed when accurate quantification is required for diagnostic purposes, such as in single g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0eb301e6c9c77572de3482856d0852
https://doi.org/10.1038/s41598-019-50378-8
https://doi.org/10.1038/s41598-019-50378-8
Autor:
Michael R. Diehl, Nicholaus J. Trenton, R. Tyler McLaughlin, Volker Schweikhard, Jordan S. Orange, Emily M. Mace, David S. Tsao, Satya K. Bellamkonda
The coordination of lipid messenger signaling with cytoskeletal regulation is central to many organelle-specific signaling and regulatory processes. While central to many aspects of cell physiology, this coupling often depends on the function of mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1dc10057021856e6662d12d54e8e46
Autor:
Rahul Shukla, Oguzhan Atay, Amy B. Nguyen, Prem N. Arora, Sukrit Silas, Vivien A. Sheehan, Nelda Itzep, Brian P. Landry, Celeste K. Kanne, David S. Tsao, Rani Sharma
Next-generation DNA sequencing is currently limited by an inability to count the number of input DNA molecules. Molecular counting is particularly needed when accurate quantification is required for diagnostic purposes, such as in single-gene non-inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca35ce0fa84f002c61b5849748555b4
https://doi.org/10.1101/597732
https://doi.org/10.1101/597732
Publikováno v:
Blood. 132:2369-2369
Introduction: Over 300,000 infants are born with sickle cell disease (SCD) every year worldwide, including at least 1,000 in the US. Prenatal diagnosis by amniocentesis or chorionic villus sampling is available; but high cost, invasiveness, and risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e9078cf244c0ee691fdb3f0f7f98427
https://doi.org/10.1182/blood-2018-99-115254
https://doi.org/10.1182/blood-2018-99-115254
Examining the collective mechanical behaviors of interacting cytoskeletal motors has become increasingly important to dissecting the complex and multifaceted mechanisms that regulate the transport and trafficking of materials in cells. Although study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993f0b6742e48b239ae94ab2163a71d0
https://doi.org/10.1016/bs.mcb.2015.01.019
https://doi.org/10.1016/bs.mcb.2015.01.019
Publikováno v:
Biophysical Journal. 112:431a
IQGAP1 is a large, multi-domain scaffold that helps orchestrate cell signaling and cytoskeletal mechanics by controlling interactions among a spectrum of receptors, signaling intermediates, and cytoskeletal proteins. While this coordination is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2980b2cc86ac7e6276a4aab86de4ed8
https://doi.org/10.1016/j.bpj.2016.11.2302
https://doi.org/10.1016/j.bpj.2016.11.2302