Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David S. Teager"'
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 7803-7808 (2018)
Externí odkaz:
https://doaj.org/article/f9f70948bb134b0b9fcb4989f0692b6c
Publikováno v:
Green Techniques for Organic Synthesis and Medicinal Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b2b4760e30a3474978e10837ad2a088
https://doi.org/10.1002/9780470711828.ch26
https://doi.org/10.1002/9780470711828.ch26
Autor:
David S. Teager, Rodger W. Stringham
Publikováno v:
Organic Process Research & Development. 16:764-768
We report an improvement to the previously published manufacturing process for artemether, a key antimalarial drug, utilizing readily available reagents, easily controlled manufacturing conditions, and a greatly simplified workup and isolation. New a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7194e1765b2135c68ac8f80200383035
https://doi.org/10.1021/op300037e
https://doi.org/10.1021/op300037e
Autor:
Christopher N. Boddy, Frajovon Talley, Stephen R. Houghton, L. Nagaprasada Rao, Jack Melton, Shaik Muneer, Nylea Bivins, Gottumukkala V. Subbaraju, David S. Teager, Adrian Williams, Tricia Silverton, Stephen R. Byrn, Nardla Gopal Reddy, K. Chandra Shekar, Daniel T. Smith, S. Tirumala Jagadeesh, David H. Brown Ripin, R. Venkateswara Rao, Puma Chandra Ray, Kelly K. Catlin, Rodger W. Stringham, Joseph M. Fortunak, Shaik Mahaboob Basha, Ravi Mallikarjuna Reddy, K. Anesh Kumar
Publikováno v:
Organic Process Research & Development. 14:1194-1201
The three-step manufacturing process used in the synthesis of tenofovir disoproxil fumarate (1) was studied and optimized, leading to a more productive and robust process. The yield was improved from about 13% overall to 24%. Key process improvements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52ee6a6c0d36118dba25441a3778323a
https://doi.org/10.1021/op1001337
https://doi.org/10.1021/op1001337
Publikováno v:
The Journal of Organic Chemistry. 58:5493-5499
Many literature examples show that the reaction of a simple cyclic ketone with (dibromomethyl)lithium at -78 o C, followed by low-temperature hydrolysis of the resulting lithium alkoxide 33, gives the corresponding dibromomethyl alcohol. We have foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25523ded403b160fd78be76f7b4a75b
https://doi.org/10.1021/jo00072a037
https://doi.org/10.1021/jo00072a037
Autor:
David S. Teager, R. K. Jun. Murray
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3547739758b36cee510554668baea201
https://doi.org/10.1002/chin.199408149
https://doi.org/10.1002/chin.199408149
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cca0894bedb4979ac6009f00d1efa3c
https://doi.org/10.1002/chin.199407117
https://doi.org/10.1002/chin.199407117
Autor:
R. K. Jun. Murray, David S. Teager
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b9dbbb59fc4b50cf4ff6e2eff4a34d
https://doi.org/10.1002/chin.199408148
https://doi.org/10.1002/chin.199408148
Autor:
David S. Teager, Neville L. Holder, Rodriguez Walter, Witold L. Tomasik, Philippe Pitchen, Benoit J. Vanasse, James P. Sherbine, Harshavadan C. Shah, David J. Taube, William L. Studt, Geoffrey A. D’Netto, Matthew R. Powers, Simon F. Golec, Anthony T. Gardetto, Woodward Rick G, Gregory C. Kubiak, Thompson Michael D, James J. Mencel, Vincent Windisch, Robert C. Liu, Diane C. Salazar, Adam W. Sledeski
Publikováno v:
Peptides for the New Millennium ISBN: 0792364457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d22c9cd23c251a18e1f477a19f06a1
https://doi.org/10.1007/0-306-46881-6_51
https://doi.org/10.1007/0-306-46881-6_51
Autor:
Roger K. Murray, David S. Teager
Publikováno v:
The Journal of Organic Chemistry. 58:5548-5550
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f220c61ee6d2f33c8308611c07b227b4
https://doi.org/10.1021/jo00072a049
https://doi.org/10.1021/jo00072a049