Zobrazeno 1 - 9
of 9
pro vyhledávání: '"David S. Rudolph"'
Drug delivery of zinc to Barrett’s metaplasia by oral administration to Barrett’s esophagus patients
Autor:
Nicole E. Albert, Dinu Cherian, Benjamin Raile, Christopher P. Farrell, John Abramson, Robert Bailey, Giancarlo Mercogliano, Mary Carmen Valenzano, Marc Zitin, Erin McDonnell, Maura Barr, James M. Mullin, E Peter Zurbach, Gary Daum, Melissa Morgan, Austin Hwang, Joanna M. Mercado, Jonathan M. Raines, James J Thornton, Xuexuan Wang, Gary Newman, David S. Rudolph
Publikováno v:
Therapeutic Delivery. 5:257-264
Background: Delivery of a pharmacologically effective drug dosage to a target tissue is critical. Barrett’s epithelia are a unique challenge for drug delivery of orally administered zinc due to rapid transit down the esophageal lumen, incomplete ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fa1fd510660f0dce864bfacfc914f1
https://doi.org/10.4155/tde.13.151
https://doi.org/10.4155/tde.13.151
Autor:
Xuexuan Wang, David S. Rudolph, James M. Mullin, Austin Hwang, Christopher P. Farrell, Nicole E. Albert, Mary Carmen Valenzano, Giancarlo Mercogliano, Melissa Morgan
Publikováno v:
Gastroenterology Research
Background: Proton pump inhibitors (PPIs) cause a sharp elevation of gastro-duodenal luminal pH which in turn has resulted in reports of reduced absorption of magnesium and certain other nutrients. Methods: Gastroesophageal reflux disease (GERD) pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882772b6a34204eb57eb4f64e0ce1ad0
http://europepmc.org/articles/PMC5139861
http://europepmc.org/articles/PMC5139861
Autor:
Giancarlo Mercogli, Keith R. Kearney, Mary Carmen Valenzano, Benjamin Ngo, David S. Rudolph, James M. Mullin
Publikováno v:
Journal of Epithelial Biology and Pharmacology. 4:7-11
Background: Our group has recently published that proton pump inhibitors (PPIs) induce transmucosal, paracellular, bidirectional leakage in the gastric corpus epithelium to a wide range of molecules. Aim: This study was undertaken to determine if H-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6814e538834b930f237b171356b3b71e
https://doi.org/10.2174/1875044301104010007
https://doi.org/10.2174/1875044301104010007
Publikováno v:
The Journal of the American Osteopathic Association. 112(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8573f3845b9faa711c704c406a760fd
https://pubmed.ncbi.nlm.nih.gov/22302744
https://pubmed.ncbi.nlm.nih.gov/22302744
Autor:
Jessica Bowers, Rong Jiang, Tom Stamato, Noor Dawany, Robert Getts, Keith R. Kearney, Keith W. Jones, Michael K. Showe, Jessica Kao, Sharon DiRienzo, David S. Rudolph, Jeremy Gollub, Radha Duttagupta
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31241 (2012)
PLoS ONE
PLoS ONE
Inflammatory Bowel Disease – comprised of Crohn's Disease and Ulcerative Colitis (UC) - is a complex, multi-factorial inflammatory disorder of the gastrointestinal tract. In this study we have explored the utility of naturally occurring circulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2005ded2078fc01e14c087dea21067da
http://europepmc.org/articles/PMC3281076?pdf=render
http://europepmc.org/articles/PMC3281076?pdf=render
Autor:
Christopher P. Farrell, James M. Mullin, Kevin Wolov, James J Thornton, Melissa Gabello, Jillan Bellows, David S. Rudolph, Keith R. Kearney, Lisa J. Murray
Publikováno v:
Drug discovery today. 14(13-14)
Proton pump inhibitors are the second most commonly prescribed drug class in the United States. The increased utilization of PPIs parallels the rising incidence of reflux disease. Owing to their clinical efficacy and relative lack of tachyphylaxis, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c61ea0f7c6d74bc74a6ef8f63fbaba8
https://pubmed.ncbi.nlm.nih.gov/19443264
https://pubmed.ncbi.nlm.nih.gov/19443264
Autor:
Aaron P. Martin, Melissa Gabello, Melissa Morgan, Christopher P. Farrell, Lisa J. Murray, James C. Underwood, David S. Rudolph, M. Carmen Valenzano, James M. Mullin
Publikováno v:
Digestive diseases and sciences. 54(7)
Despite their remarkable safety profile and lack of clinical side effects, proton pump inhibitors (PPIs) induce a transmucosal gastric leak to non-electrolyte probes of various sizes. The ex vivo addition of PPIs to isolated rat gastric corpus increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84115944b4f0615852708afb35bc8e27
https://pubmed.ncbi.nlm.nih.gov/19015985
https://pubmed.ncbi.nlm.nih.gov/19015985
Publikováno v:
European Journal of Haematology. 88:367-368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63742ae05a0c757e35cb3e0f70b78e0a
https://doi.org/10.1111/j.1600-0609.2012.01752.x
https://doi.org/10.1111/j.1600-0609.2012.01752.x
Autor:
James J. Thornton, Giancarlo Mercogliano, Lisa J Murray, James M. Mullin, Marysue Whitby, Mary Carmen Valenzano, David S. Rudolph, Owen Tully
Publikováno v:
World Journal of Gastroenterology. 14:1365
AIM: To evaluate the presence of Na+-dependent, active, sugar transport in Barrett's epithelia as an intestinal biomarker, based on the well-documented, morphological intestinal phenotype of Barrett's esophagus (BE). METHODS: We examined uptake of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf67776747c8c5a0f56b3a4f4afeb28
https://doi.org/10.3748/wjg.14.1365
https://doi.org/10.3748/wjg.14.1365