Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David S. Ramirez"'
Autor:
Donglin Guo, Bernard Fermini, David S. Ramirez, Stephen Jenkinson, Asser Bassyouni, Jason Cordes, Todd Wisialowski, Sunny Z. Sun, David M. Potter, Jill Steidl-Nichols
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 89:9-18
Introduction Cardiac sodium channel antagonists have historically been used to treat cardiac arrhythmias by preventing the reentry of the electrical impulse that could occur following myocardial damage. However, clinical studies have highlighted a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af8646dabdbc80e028ae938b088d883
https://doi.org/10.1016/j.vascn.2017.10.002
https://doi.org/10.1016/j.vascn.2017.10.002
Autor:
Asser Bassyouni, Sunny Z. Sun, Michelle Hemkens, Bernard Fermini, Todd Wisialowski, David S. Ramirez, Stephen Jenkinson
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 84:86-92
Introduction Although therapeutically beneficial in the treatment of certain diseases, L-type calcium channel antagonism can result in unwanted off-target pharmacology leading to adverse drug reactions and to the termination of the development of oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc60b802e3079ed6b76810c933766e1d
https://doi.org/10.1016/j.vascn.2016.11.002
https://doi.org/10.1016/j.vascn.2016.11.002
Autor:
Gregory W. Kauffman, Edelweiss Evrard, Eddie Yang, Betty Pettersen, Danica A. Rankic, Stefanus J. Steyn, David S. Ramirez, Eva Hajos-Korcsok, Douglas S. Johnson, Kelly R. Bales, Leslie R. Pustilnik, Christopher W. am Ende, Patrick Robert Verhoest, Christopher John Helal, Martin Pettersson, Kathleen M. Wood, Antonia F. Stepan, Brian P. Boscoe, Cory Michael Stiff, John M. Humphrey, Longfei Xie, Stephen Jenkinson, Butler Todd W
Publikováno v:
MedChemComm. 8(4)
Herein we describe the discovery of a novel series of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators for the treatment of Alzheimer's disease (AD). Using ligand-based design tactics such as conformational analysis and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8984ff654384ff6bcc05fe91df8016da
https://pubmed.ncbi.nlm.nih.gov/30108792
https://pubmed.ncbi.nlm.nih.gov/30108792
Autor:
Laura E. Waggoner, Daniel S. Poole, P. Alexandra Treschow, David S. Ramirez, Jinah Kim, William R Schafer, Anthony Kempf
Publikováno v:
Genetics. 157:1599-1610
Egg-laying behavior in Caenorhabditis elegans is regulated by multiple neurotransmitters, including acetylcholine and serotonin. Agonists of nicotinic acetylcholine receptors such as nicotine and levamisole stimulate egg laying; however, the genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635f84336ffb51dcbf2f696e27df5ea3
https://doi.org/10.1093/genetics/157.4.1599
https://doi.org/10.1093/genetics/157.4.1599
Autor:
William P. Gorczyca, David S. Ramirez, Asser Bassyouni, Stephen Foote, Michelle Hemkens, Todd Wisialowski, Sunny Z. Sun, Stephen Jenkinson
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e48-e49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18cbe4da7b95f5fccec6d0f18f7cc42b
https://doi.org/10.1016/j.vascn.2013.01.174
https://doi.org/10.1016/j.vascn.2013.01.174
Autor:
Jill Steidl-Nichols, David S. Ramirez, Amy Rosado, Jason Cordes, Bernard Fermini, Stephen Jenkinson
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64dd7de43289a43f2a8ec148bed5c585
https://doi.org/10.1016/j.vascn.2013.01.082
https://doi.org/10.1016/j.vascn.2013.01.082
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e83332d122fdcbe746fe1fb8723da70
https://doi.org/10.1016/j.vascn.2012.08.080
https://doi.org/10.1016/j.vascn.2012.08.080
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 62:e12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a035dd2af369f35bbc17dc97daff176
https://doi.org/10.1016/j.vascn.2010.11.041
https://doi.org/10.1016/j.vascn.2010.11.041
Autor:
Ray Liu, Neil Brunton, David S. Ramirez, Aileen McHarg, Jonathan R. Heyen, Jon Scatchard, Kirk Kozminski, Mike Zager
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 60:251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c7460a0111b85ef16408229ba1e14d
https://doi.org/10.1016/j.vascn.2009.04.170
https://doi.org/10.1016/j.vascn.2009.04.170
Autor:
David S. Ramirez, Michelle Hemkens, Aileen McHarg, S. Patyna, Jill Steidl, K. Wilkinson, Eileen R. Blasi, Jonathan R. Heyen
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 58:172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23cf0a919c34e85086ce13009a6b4e63
https://doi.org/10.1016/j.vascn.2008.05.108
https://doi.org/10.1016/j.vascn.2008.05.108