Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David S. Peal"'
Autor:
Jonathan T. Butcher, David J. Milan, Emily J. Farrar, David S. Peal, Emilye Hiriart, Ablajan Mahmut, Michel Pucéat, Bernd Jagla
Publikováno v:
Science Advances
Science Advances, 2021, 7 (45), pp.eabf7910. ⟨10.1126/sciadv.abf7910⟩
Science Advances, 2021, 7 (45), pp.eabf7910. ⟨10.1126/sciadv.abf7910⟩
Description
Cell reprogramming is at the origin of valve calcification.
Cell plasticity plays a key role in embryos by maintaining the differentiation potential of progenitors. Whether postnatal somatic cells revert to an embryonic-like na
Cell reprogramming is at the origin of valve calcification.
Cell plasticity plays a key role in embryos by maintaining the differentiation potential of progenitors. Whether postnatal somatic cells revert to an embryonic-like na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab35d94da46fd4aaf418e0ae93d1d5fb
https://pubmed.ncbi.nlm.nih.gov/34739324
https://pubmed.ncbi.nlm.nih.gov/34739324
Autor:
Yaopan Mao, Katelynn Toomer, Charles Simpson, David J. Milan, David S. Peal, Francesca N. Delling, Roger R. Markwald, Jorge Solis, Maelle Perrocheau, Ronen Durst, Lisa A. Freed, Amanda J. Johnson, Annemarieke DeVlaming, Christopher Jett, Xavier Estivill, Leticia Fernández-Friera, Adrian H. Chester, Michel Pucéat, Matthew R. Stone, Maire Leyne, Thierry Le Tourneau, Susan A. Slaugenhaupt, Christian Dina, Jean-Jacques Schott, Monica Salani, Kenneth D. Irvine, Katherine Williams, Kimberly Sauls, Andy Wessels, Yoshikazu Tsukasaki, Daniel Trujillano, Xingju Nie, Herve LeMarec, Florie A. Charles, Patrick Bruneval, Donald R. Menick, Robert A. Levine, Stephan Ossowski, Russell A. Norris, Michael E. Talkowski, Harinath Kasiganesan, Nabila Bouatia-Naji, Ann-Marie Broome, Stacey N. Lynch, Tahirali Motiwala, Harrison Brand, Christophe Tribouilloy, Colby Chiang, Albert Hagège, Xavier Jeunemaitre
Publikováno v:
Nature
Nature, 2015, Equipe 3, 525 (7567), pp.109--113. ⟨10.1038/nature14670⟩
Nature, Nature Publishing Group, 2015, Equipe 3, 525 (7567), pp.109--113. ⟨10.1038/nature14670⟩
Nature, 2015, Equipe 3, 525 (7567), pp.109--113. ⟨10.1038/nature14670⟩
Nature, Nature Publishing Group, 2015, Equipe 3, 525 (7567), pp.109--113. ⟨10.1038/nature14670⟩
International audience; Mitral valve prolapse (MVP) is a common cardiac valve disease that affects nearly 1 in 40 individuals. It can manifest as mitral regurgitation and is the leading indication for mitral valve surgery. Despite a clear heritable c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6591f59e92317fa7a60159dfd5e0c478
http://europepmc.org/articles/PMC4720389
http://europepmc.org/articles/PMC4720389
Autor:
Russell A. Norris, Heather J. Kolpa, David S. Peal, Roger R. Markwald, Andrea C. Giokas, Calum A. MacRae, Joyce Bischoff, David J. Milan, Patrick T. Ellinor, Shibnath Ghatak, Stacey N. Lynch, Suniti Misra
Publikováno v:
Development. 140:2172-2180
The discovery of small non-coding microRNAs has revealed novel mechanisms of post-translational regulation of gene expression, the implications of which are still incompletely understood. We focused on microRNA 21 (miR-21), which is expressed in card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b03474b1494a51c47cf3d463f439e3
https://doi.org/10.1242/dev.084475
https://doi.org/10.1242/dev.084475
Publikováno v:
Journal of Cardiovascular Translational Research. 4:720-726
Proper atrioventricular canal (AVC) patterning and subsequent valvulogenesis is a complex process, and defects can result in disease or early death. The zebrafish Danio rerio has become a useful model system for studying AVC development, and much pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ede53a0393156e95079e2e22a9ba35e
https://doi.org/10.1007/s12265-011-9313-z
https://doi.org/10.1007/s12265-011-9313-z
Publikováno v:
Developmental Dynamics. 238:3103-3110
Defects in cardiac valvulogenesis are a common cause of congenital heart disease, and the study of this process promises to provide mechanistic insights and lead to novel therapeutics. Normal valve development involves multiple signaling pathways, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49dd413addfbc19478a654dc76d787c4
https://doi.org/10.1002/dvdy.22154
https://doi.org/10.1002/dvdy.22154
Autor:
Mark D. Handschumacher, David P. Milan, Patrick Bruneval, Magdi H. Yacoub, Harry C. Dietz, Hervé Le Marec, Robert A. Levine, Jean Mérot, Maelle Perrocheau, David S. Peal, Francesca N. Delling, Nadia Rosenthal, Vincent Probst, Albert Hagège, Jonathan Beaudoin, Joyce Bischoff, Russell A. Norris, Leticia Fernández-Friera, Jacob P. Dal-Bianco, Miguel Chaput, Catherine Clusel, Morten O. Jensen, Thierry Le Tourneau, Muralidhar Padala, Xavier Jeunemaitre, Emmanuel Messas, Susan A. Slaugenhaupt, Roger R. Markwald, Jorge Solis, Jae-Kwan Song, Christian Dina, Jonathan T. Butcher, Jean-Jacques Schott, Tui Neri, Alain Carpentier, Daniel P. Judge, Nabila Bouatia-Naji, Ronen Durst, Adrian H. Chester, Elena Aikawa, Michael Pucéat, Ehud Schwammenthal
Publikováno v:
Nature Reviews Cardiology
Nature Reviews Cardiology, Nature Publishing Group, 2015, 12 (12), pp.689--710. ⟨10.1038/nrcardio.2015.161⟩
Nature Reviews Cardiology, 2015, 12 (12), pp.689--710. ⟨10.1038/nrcardio.2015.161⟩
Nature Reviews Cardiology, Nature Publishing Group, 2015, 12 (12), pp.689--710. ⟨10.1038/nrcardio.2015.161⟩
Nature Reviews Cardiology, 2015, 12 (12), pp.689--710. ⟨10.1038/nrcardio.2015.161⟩
International audience; Mitral valve disease is a frequent cause of heart failure and death. Emerging evidence indicates that the mitral valve is not a passive structure, but−even in adult life−remains dynamic and accessible for treatment. This c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9db727cea38a3651b7055d8eddf782f
https://hal.archives-ouvertes.fr/hal-01830969/document
https://hal.archives-ouvertes.fr/hal-01830969/document
Autor:
R. J. F. Loos, Ruth J. F. Loos, Ody C. M. Sibon, Toby Johnson, David S. Peal, Harm-Jan Westra, Marcel den Hoed, Robert E. Handsaker, Alicia Lundby, Tõnu Esko, Peter M. Visscher, Cristen J. Willer, Lude Franke, Ayellet V. Segrè, David J. Milan, Mark Eijgelsheim, Nilesh J. Samani, Harold Snieder, Jian Yang
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6143f1b6b0eb3292c8c0c826b1772c9d
https://doi.org/10.1038/protex.2013.041
https://doi.org/10.1038/protex.2013.041
Autor:
Janet M. Mosley, David S. Peal, Robert W. Mills, Evi Lim, David J. Milan, Craig T. January, Randall T. Peterson, Stacey N. Lynch, Patrick T. Ellinor
Background— Genetic long QT (LQT) syndrome is a life-threatening disorder caused by mutations that result in prolongation of cardiac repolarization. Recent work has demonstrated that a zebrafish model of LQT syndrome faithfully recapitulates severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fad1dde23bf3d4183bb8184ec538057
https://europepmc.org/articles/PMC3015011/
https://europepmc.org/articles/PMC3015011/
Autor:
Wong, Chi-Huey
Publikováno v:
Carbohydrate-Based Drug Discovery, 2 Volume Set; 2003, p501-516, 16p
Publikováno v:
Journal of Cardiovascular Translational Research; Dec2011, Vol. 4 Issue 6, p720-726, 7p