Zobrazeno 1 - 10
of 29
pro vyhledávání: '"David S. McNabb"'
Publikováno v:
BioTechniques, Vol 22, Iss 6, Pp 1134-1139 (1997)
The ability to conveniently construct gene disruptions is an important methodology for genetic analysis of the fission yeast Schizosaccharomyces pombe. Because of the limited number of selectable markers available for generating gene disruptions in f
Externí odkaz:
https://doaj.org/article/64f15bd1793d45639144ef995b318276
Publikováno v:
ACS Sensors. 4:100-109
In this work, using a silicon nitride nanopore based device, we measure the binding locations of RNA Polymerase (RNAP) on 48.5 kbp (16.5 μm) long λ DNA. To prevent the separation of bound RNAPs from a λ DNA molecule in the high electric field insi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04781e5de41d9c5d57a7258ab3c3ede2
https://doi.org/10.1021/acssensors.8b00976
https://doi.org/10.1021/acssensors.8b00976
Publikováno v:
Antimicrob Agents Chemother
The incidence of opportunistic fungal infections that threaten immunocompromised patients, along with the limited arsenal of antifungal drugs, calls for renewed efforts to develop novel antifungal therapies. Antimicrobial peptides have garnered inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9582484f91ac527af05f78bcee3c1602
https://pubmed.ncbi.nlm.nih.gov/31843998
https://pubmed.ncbi.nlm.nih.gov/31843998
Autor:
Shilpi Agrawal, Gayatri Suresh Kumar, Bhanu prasanth Koppolu, Ravi Kumar Gundampati, David S. McNabb, David A. Zaharoff, Srinivas Jayanthi, Thallapuranam Krishnaswamy Suresh Kumar, Rebecca Kerr, Sanhita Maity
Publikováno v:
Biochemical and biophysical research communications. 518(2)
Acidic fibroblast growth factors (FGF1s) are heparin binding proteins that regulate a wide array of key cellular processes and are also candidates for promising biomedical applications. FGF1-based therapeutic applications are currently limited due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cd9762769a1ec54b6d759cf91f139c
https://pubmed.ncbi.nlm.nih.gov/31420170
https://pubmed.ncbi.nlm.nih.gov/31420170
Autor:
Jacqueline Morris, Ralph Henry, Srinivas Jayanthi, David S. McNabb, Alicia Kight, Rebekah G. Langston, Thallapuranam Krishnaswamy Suresh Kumar, Anna E. Daily
Publikováno v:
Protein Expression and Purification. 126:93-103
Purification of recombinant proteins constitutes a significant part of the downstream processing in biopharmaceutical industries. Major costs involved in the production of bio-therapeutics mainly depend on the number of purification steps used during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa70f25a18fade8745e6b857a3f3fd41
https://doi.org/10.1016/j.pep.2016.05.013
https://doi.org/10.1016/j.pep.2016.05.013
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170649 (2017)
PLoS ONE
PLoS ONE
Candida albicans is the most frequently encountered fungal pathogen in humans, capable of causing mucocutaneous and systemic infections in immunocompromised individuals. C. albicans virulence is influenced by multiple factors. Importantly, iron acqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106512c1b9cb8aadb9aa3ae19ceae768
http://europepmc.org/articles/PMC5266298?pdf=render
http://europepmc.org/articles/PMC5266298?pdf=render
Autor:
Jiali Li, Changbae Hyun, Harpreet Kaur, Min Xiao, Tao Huang, David S. McNabb, Santoshi Nandivada
Publikováno v:
Biophysical Journal. 110(3)
We report our study to detect the binding sites of RNAP Holoenzyme on λ DNA molecules with an apparatus that integrates a Solid State Nanopore (SSN) with a Tuning Fork based Force sensing Probe tip (SSN-TFFSP). Using this apparatus, we can control t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08296ab385ce55c5e84678db700d1fb6
Autor:
Rudra Palash Mukherjee, David S. McNabb, Srinivas Jayanthi, Thallapuranam Krishnaswamy Suresh Kumar, Robert R. Beitle
Publikováno v:
Biotechnology progress. 32(4)
Interest in peptides as diagnostic and therapeutic materials require their manufacture via either a recombinant or synthetic route. This study examined the former, where a recombinant fusion consisting of an antifungal peptide was expressed and isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e59b65a60e166ba918e770248a44bc
https://pubmed.ncbi.nlm.nih.gov/27162203
https://pubmed.ncbi.nlm.nih.gov/27162203
Publikováno v:
ELECTROPHORESIS. 33:3448-3457
In this work, we report on how salt concentration and cation species affect DNA translocation in voltage-biased silicon nitride nanopores. The translocation of dsDNA in linear, circular, and supercoiled forms was measured in salt solutions containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28284bf5e80ac5c8ff51661ab22fbd6c
https://doi.org/10.1002/elps.201200165
https://doi.org/10.1002/elps.201200165
Publikováno v:
International Journal of Knowledge Discovery in Bioinformatics. 1:50-73
In this paper, the authors present a wavelet-based algorithm (Wave-SOM) to help visualize and cluster oscillatory time-series data in two-dimensional gene expression micro-arrays. Using various wavelet transformations, raw data are first de-noised by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13d51a6c92593180e36715d56a1111b
https://doi.org/10.4018/jkdb.2010040104
https://doi.org/10.4018/jkdb.2010040104