Zobrazeno 1 - 10
of 156
pro vyhledávání: '"David S. Li"'
Autor:
Hao Liu, João S. Soares, John Walmsley, David S. Li, Samarth Raut, Reza Avazmohammadi, Paul Iaizzo, Mark Palmer, Joseph H. Gorman, Robert C. Gorman, Michael S. Sacks
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Myocardial infarction (MI) rapidly impairs cardiac contractile function and instigates maladaptive remodeling leading to heart failure. Patient-specific models are a maturing technology for developing and determining therapeutic modalities f
Externí odkaz:
https://doaj.org/article/82d45691d36245a6ae9cd5b612ac0300
Autor:
Geng-Shi Jeng, Meng-Lin Li, MinWoo Kim, Soon Joon Yoon, John J. Pitre, David S. Li, Ivan Pelivanov, Matthew O’Donnell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Spectroscopic photoacoustic imaging has been limited by wavelength-dependent fluence variations and tissue motion. Here, the authors achieve real-time fluence and motion correction in vivo by using a wavelength-tunable laser, sequential scan of a nar
Externí odkaz:
https://doaj.org/article/8269cdc25c00487f809f0633b510b90d
Autor:
John J. Pitre, Mitchell A. Kirby, David S. Li, Tueng T. Shen, Ruikang K. Wang, Matthew O’Donnell, Ivan Pelivanov
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract The cornea provides the largest refractive power for the human visual system. Its stiffness, along with intraocular pressure (IOP), are linked to several pathologies, including keratoconus and glaucoma. Although mechanical tests can quantify
Externí odkaz:
https://doaj.org/article/1a40301052aa4ca193d2e433e87d4622
Autor:
Mitchell A. Kirby, PhD, John J. Pitre, Jr., PhD, Hong-Cin Liou, PhD, David S. Li, PhD, Ruikang K. Wang, PhD, Ivan Pelivanov, PhD, Matthew O’Donnell, PhD, Tueng T. Shen, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 1, Iss 4, Pp 100058- (2021)
Purpose: To compare noncontact acoustic microtapping (AμT) OCT elastography (OCE) with destructive mechanical tests to confirm corneal elastic anisotropy. Design: Ex vivo laboratory study with noncontact AμT-OCE followed by mechanical rheometry and
Externí odkaz:
https://doaj.org/article/305b9771e6b1431788b6cef171f39127
Publikováno v:
Photoacoustics, Vol 20, Iss , Pp 100202- (2020)
Sono-photoacoustic (SPA) activation lowers the threshold of phase-change contrast agents by timing a laser shot to coincide with the arrival of an acoustic wave at a region of interest. The combination of photothermal heating from optical absorption
Externí odkaz:
https://doaj.org/article/ab338c1e76244ce089671da2b9a32428
Publikováno v:
The Journal of the Acoustical Society of America. 152(4)
Perfluorocarbon nanodroplets (PFCnDs) are ultrasound contrast agents that phase-transition from liquid nanodroplets to gas microbubbles when activated by laser irradiation or insonated with an ultrasound pulse. The dynamics of PFCnDs can vary drastic
Autor:
Sae-Il Murtada, Yuki Kawamura, Cristina Cavinato, Molly Wang, Abhay B. Ramachandra, Bart Spronck, David S. Li, George Tellides, Jay D. Humphrey
Publikováno v:
Biomechanics and Modeling in Mechanobiology.
Hutchinson-Gilford Progeria Syndrome results in rapid aging and severe cardiovascular sequelae that accelerate near end-of-life. We found a progressive disease process in proximal elastic arteries that was less evident in distal muscular arteries. Ch
Autor:
Minghao Chen, Cristina Cavinato, Jens Hansen, Keiichiro Tanaka, Pengwei Ren, Abdulrahman Hassab, David S. Li, Eric Youshao, George Tellides, Ravi Iyengar, Jay D. Humphrey, Martin A. Schwartz
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43
Background: Marfan syndrome, caused by mutations in the gene for fibrillin-1, leads to thoracic aortic aneurysms (TAAs). Phenotypic modulation of vascular smooth muscle cells (SMCs) and ECM (extracellular matrix) remodeling are characteristic of both
Autor:
Sae-Il Murtada, Nicole Mikush, Mo Wang, Pengwei Ren, Yuki Kawamura, Abhay B Ramachandra, David S Li, Demetrios T Braddock, George Tellides, Leslie B Gordon, Jay D Humphrey
Publikováno v:
eLife. 12
Clinical trials have demonstrated that lonafarnib, a farnesyltransferase inhibitor, extends the lifespan in patients afflicted by Hutchinson-Gilford progeria syndrome, a devastating condition that accelerates many characteristics of aging and results
Autor:
Christian Goodbrake, David S. Li, Hossein Aghakhani, Alejandro Contreras, Gregory P. Reece, Mia K. Markey, Michael S. Sacks
Publikováno v:
Ann Biomed Eng
As the human breast undergoes complex, large-scale, fully three dimensional deformations in vivo, three-dimensional (3D) characterization of its mechanical behavior is fundamental to its diagnosis, treatment, and surgical modifications. Its anisotrop