Zobrazeno 1 - 10
of 21
pro vyhledávání: '"David S. Chervinsky"'
Autor:
Sei Ichi Matsui, Hai Shen Chen, Norma J. Nowak, John K. Cowell, Michael R. Rossi, Daniel Gaile, Jeffrey M. Conroy, Gene H. Barnett, Roger L. Eddy, David S. Chervinsky, Devin McQuaid, Jeffrey LaDuca
Publikováno v:
Genes, Chromosomes and Cancer. 44:85-96
We have analyzed 18 low-grade gliomas using array comparative genomic hybridization (aCGH) with an average resolution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f79e3fae5a5b34ffffe38d53efd808
https://doi.org/10.1002/gcc.20218
https://doi.org/10.1002/gcc.20218
Publikováno v:
Molecular and Cellular Biology. 17:4070-4079
A distinct population of therapy-related acute myeloid leukemia (t-AML) is strongly associated with prior administration of topoisomerase II (topo II) inhibitors. These t-AMLs display distinct cytogenetic alterations, most often disrupting the MLL ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae785762f7eb3fc73159ec309739d72
https://doi.org/10.1128/mcb.17.7.4070
https://doi.org/10.1128/mcb.17.7.4070
Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus
Publikováno v:
Leukemia. 11:490-496
Treatment-related acute myeloid leukemia (t-AML) following successful therapy of a primary malignancy has been recognized with increasing frequency among cancer survivors over the past several years. Many of these t-AML cases are associated with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0386ccb5104522e3beec99b06d851e1
https://doi.org/10.1038/sj.leu.2400632
https://doi.org/10.1038/sj.leu.2400632
Publikováno v:
Blood. 87:2649-2658
The MLL gene located at 11q23 is frequently disrupted by chromosomal translocation in a wide spectrum of newly diagnosed acute leukemias. Recently, it has become apparent that the MLL gene is very frequently disrupted by chromosomal translocations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6b4a89d3db771d2f8cb6f94667d56db
https://doi.org/10.1182/blood.v87.7.2649.bloodjournal8772649
https://doi.org/10.1182/blood.v87.7.2649.bloodjournal8772649
Autor:
Brenda Lauffart, David S. Chervinsky, Mary M. Vaughan, Ivan H. Still, Richard A. DiCioccio, Roger L. Eddy, Jennifer D. Black
Publikováno v:
BMC Women's Health
BMC Women's Health, Vol 5, Iss 1, p 8 (2005)
BMC Women's Health, Vol 5, Iss 1, p 8 (2005)
BackgroundDysregulation of the human Transforming Acidic Coiled Coil (TACC) genes is thought to be important in the development and progression of multiple myeloma, breast and gastric cancer. Recent, large-scale genomic analysis and Serial Analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c61ecccd654c117c3dca540600cded
https://doi.org/10.1186/1472-6874-5-8
https://doi.org/10.1186/1472-6874-5-8
Publikováno v:
Genes, chromosomescancer. 37(3)
MLL gene rearrangements leading to production of MLL fusion proteins are commonly detected in infant leukemia patients; the most common MLL fusion associated with infant leukemia is the MLL-AF4 fusion. A single case of chromosomal rearrangement leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e7d8e515cc493e4216ad19b2737a4a
https://pubmed.ncbi.nlm.nih.gov/12759932
https://pubmed.ncbi.nlm.nih.gov/12759932
Autor:
Gerold Bepler, Ashish Gautam, Lauren M. McIntyre, Amy F. Beck, David S. Chervinsky, Young-Chul Kim, Diana M. Pitterle, Andrew Hyland
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(5)
PURPOSE: The assessment of prognosis and decisions on treatment for patients with non–small-cell lung cancer (NSCLC) are determined on the basis of disease stage and performance status. NSCLC frequently manifests loss of heterozygosity (LOH) at chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6d0e6d1c04b8da9b2f924cfca84e30
https://pubmed.ncbi.nlm.nih.gov/11870179
https://pubmed.ncbi.nlm.nih.gov/11870179
Publikováno v:
Leukemia. 15(1)
We have established a panel of nine immortal cell lines from T cell malignancies which arose in mice transgenic for the SCL and LMO1 genes. Cells from the primary malignancies initially grew very slowly in vitro, loosely attached to a stromal layer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d96b58743065ca9c5decef271275202
https://pubmed.ncbi.nlm.nih.gov/11243382
https://pubmed.ncbi.nlm.nih.gov/11243382
Autor:
Peter D. Aplan, Du H. Lam, Kenneth W. Gross, David S. Chervinsky, Xian-Feng Zhao, MaryKay Ellsworth
Publikováno v:
Molecular and cellular biology. 19(7)
The gene most commonly activated by chromosomal rearrangements in patients with T-cell acute lymphoblastic leukemia (T-ALL) is SCL/tal. In collaboration with LMO1 or LMO2, the thymic expression of SCL/tal leads to T-ALL at a young age with a high deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d2844bc3b8c6f5f7d59e7d74fc555f
https://pubmed.ncbi.nlm.nih.gov/10373552
https://pubmed.ncbi.nlm.nih.gov/10373552
Autor:
Peter D. Aplan, David S. Chervinsky, Kenneth W. Gross, Xian-Feng Zhao, Elizabeth A. McGuire, Chuanzen Wu, Craig A. Jones, MaryKay Ellsworth
Publikováno v:
The EMBO journal. 16(9)
The product of the scl (also called tal-1 or TCL5) gene is a basic domain, helix-loop-helix (bHLH) transcription factor required for the development of hematopoietic cells. Additionally, scl gene disruption and dysregulation, by either chromosomal tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f110456593677a46e0d196f244d558d1
https://pubmed.ncbi.nlm.nih.gov/9171354
https://pubmed.ncbi.nlm.nih.gov/9171354