Výsledky vyhledávání - "David S. Chance"

Hypolipidemic agents alter hepatic mitochondrial respiration in vitro

Autor: Michael McIntosh, David S. Chance

Publikováno v: Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 111:317-323

The direct effects of three different classes of structurally diverse hypolipidemic agents on respiration were studied in mitochondria isolated from donor Sprague-Dawley rats. Two classes of peroxisome proliferators (i.e. plasticizers and hypolipidem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fb0e48a310638d2422f6306dd76c35
https://doi.org/10.1016/0742-8413(95)00056-t

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Inverse Relationship Between Peroxisomal and Mitochondrial -Oxidation in HepG2 Cells Treated with Dehydroepiandrosterone and Clofibric Acid

Autor: David S. Chance, M. K. McIntosh, Shih-Min Wu

Publikováno v: Experimental Biology and Medicine. 208:378-384

A transformed human hepatoma cell line was examined to determine if it was an appropriate model system for studying the mechanism of action of two peroxisome proliferators that lower blood lipids. Cultures of HepG2 cells were exposed to four differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b64df286e901ad5aa6b592cd9a9db0
https://doi.org/10.3181/00379727-208-43865

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Grape extract inhibits lipid peroxidation of human low density lipoprotein

Autor: George Loo, David S. Chance, Chen Chen, Lorraine Lanninghamfoster

Publikováno v: Biologicalpharmaceutical bulletin. 18(10)

Some epidemiological data have linked dietary polyphenols with lower risk of coronary heart disease. Polyphenols might impair lipoprotein oxidation which is believed to be an important step in initiating atherogenesis. The purpose of this study was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43edcb61db19b9beb32ae93b8238ccdc
https://pubmed.ncbi.nlm.nih.gov/8593434

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Rates of beta-oxidation of fatty acids of various chain lengths and degrees of unsaturation in highly purified peroxisomes isolated from rat liver

Autor: David S. Chance, Michael McIntosh

Publikováno v: Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 109(2-3)

Highly purified peroxisomes were obtained from the liver of untreated rats, and rates of peroxisomal beta-oxidation were measured using fatty acyl-CoAs differing in chain length and degree of unsaturation. A 20–24-fold purification of peroxisomes,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68f52b9b29b356f22e1d0a37a34298b
https://pubmed.ncbi.nlm.nih.gov/7553345

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