Zobrazeno 1 - 10
of 24
pro vyhledávání: '"David S. Pugh"'
Autor:
Tessa Keenan, Glenn A. Hurst, Philip A. Helliwell, Robin Brabham, R.J. Spears, David S. Pugh, Alison Parkin, Nicholas D. J. Yates, Martin A. Fascione
Publikováno v:
Journal of Chemical Education. 96:1245-1249
A laboratory experiment introducing the concept of chemical bioconjugation of proteins to undergraduate students in a therapeutically relevant context was developed. Initially, students installed an aldehyde functionality into a protein via the oxida
Publikováno v:
AIP Conference Proceedings.
Barium stannate (BaSnO3) was prepared by solid state ceramic route. The crystalline phase of the prepared sample was confirmed by X-Ray Diffraction (XRD) pattern. Gas sensing behaviour of barium stannate was investigated for reducing and oxidizing ga
Autor:
Vilius Franckevicius, David S. Pugh, James D. Cuthbertson, Richard J. K. Taylor, Mark Pickworth
Publikováno v:
Organic Letters. 13:4264-4267
An asymmetric decarboxylative palladium-catalyzed allylation of alkyl- and aryl-substituted oxindoles has been developed, enabling the installation of an all-carbon quaternary chiral center at the oxindole 3-position in excellent yields and good to e
Publikováno v:
Tetrahedron Letters. 52:2511-2514
A one-pot oxidation/allylation/oxidation procedure has been developed for the conversion of primary alcohols into β,γ-unsaturated ketones. The methodology has been applied to a range of alcohols, and in some cases, isomerisation to produce the corr
Publikováno v:
Organic Letters. 12:3446-3449
The preparation of 3,3-disubstituted oxindoles by a formal C-H, Ar-H coupling of anilides is described. Highly efficient conditions have been identified using catalytic (5 mol %) Cu(OAc)(2).H(2)O with atmospheric oxygen as the reoxidant; no additiona
Publikováno v:
Synlett. 2010:934-938
A novel route for the conversion of anilides into 3-alkyl-oxindoles is described in which a copper(II)-mediated cyclization process is followed by an acid-mediated decarboxyalkylation. Scope and limitation studies are reported together with a telesco
Publikováno v:
Synlett. 2010:602-606
Two consecutive tandem processes are described for the regioselective, two-step synthesis of 1,3,5-trisubstituted pyrazoles from α-hydroxyketones. The first, a tandem MnO 2 -mediated oxidation/Ramirez olefination reaction, provides a facile route to
gem-Dimethylcyclopropanation Using Triisopropylsulfoxonium Tetrafluoroborate: Scope and Limitations
Autor:
Michael G. Edwards, Richard J. Paxton, David S. Pugh, Richard J. K. Taylor, Adrian C. Whitwood
Publikováno v:
Synthesis. 2008:3279-3288
A new nucleophilic isopropyl transfer reagent, triisopro- pylsulfoxonium tetrafluoroborate, has been prepared and evaluated. Thus, using this reagent and NaH in DMF, a range of electron defi- cient alkenes, including several chalcone analogues, a,b-u
Publikováno v:
Synlett. 2008:521-524
A new procedure for the cyclopropanation of α,β-unsaturated carbonyl compounds and related systems is described which employs triisopropylsulfoxonium tetrafluoroborate and sodium hydride in dimethylformamide. Using this reagent, a range of α,β-un
Autor:
Richard J. K. Taylor, David S. Pugh
Publikováno v:
Organic Syntheses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::056a8a18a112203338f5cf17d0147a6b
https://doi.org/10.1002/0471264229.os089.42
https://doi.org/10.1002/0471264229.os089.42