Zobrazeno 1 - 10
of 283
pro vyhledávání: '"David S. Grierson"'
Autor:
Cunjie Chang, Muthukumar Rajasekaran, Yiting Qiao, Heng Dong, Yu Wang, Hongping Xia, Amudha Deivasigamani, Minjie Wu, Karthik Sekar, Hengjun Gao, Mengqing Sun, Yuqin Niu, Qian Li, Lin Tao, Zhen Yan, Menglan Wang, Shasha Chen, Shujuan Zhao, Dajing Chen, Lina Li, Fan Yang, Haojin Gao, Baodong Chen, Ling Su, Liang Xu, Ye Chen, Veerabrahma Pratap Seshachalam, Gongxing Chen, Jayantha Gunaratne, Wanjin Hong, Junping Shi, Gongying Chen, David S. Grierson, Benoit Chabot, Tian Xie, Kam Man Hui, Jianxiang Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Alternative splicing is dysregulated in hepatocellular carcinoma. Here, the authors investigate the role of the splice variant of Splicing Regulatory Glutamic Acid and Lysine Rich Protein 1 (SREK1) and its upstream regulator, Serine/arginine-rich spl
Externí odkaz:
https://doaj.org/article/899e96a6dffd4ad49c98b29c783e660e
Publikováno v:
The Journal of Organic Chemistry. 86:6381-6389
In projected structure-activity relationship studies of the novel diheteroarylamide-based anti-HIV agent 2 (1C8), one objective was to evaluate the influence of incorporating the central amide motif in 2 into a five-membered pyrazolone ring, as found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e56528b81c7af042fa073ecdcb4ee7
https://doi.org/10.1021/acs.joc.1c00118
https://doi.org/10.1021/acs.joc.1c00118
Publikováno v:
Metallurgical and Materials Transactions A. 52:2463-2476
We explore the effects of thermo-chemical aluminization on wear resistance of candidate alloys Incoloy 800HT and Inconel 617 for high-temperature gas-cooled reactor (HTGR) components. Aluminized samples were conditioned for 22 days in a once-through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2026eb2235353f421be02d0a21453a63
https://doi.org/10.1007/s11661-021-06236-2
https://doi.org/10.1007/s11661-021-06236-2
Autor:
Zabrina L. Brumme, Mark A. Brockman, Peter Cheung, Benoit Chabot, David S. Grierson, Alan Cochrane, Maryam Zamiri
Publikováno v:
ACS Med Chem Lett
[Image: see text] The observation that stilbene 3 (5350150) blocks HIV replication through its impact on HIV mRNA processing prompted a program to develop non-cytotoxic analogues that maintain its mechanism of action. This initially involved replacem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a5d9aa2a55dda934e453039796d201
https://europepmc.org/articles/PMC8591739/
https://europepmc.org/articles/PMC8591739/
Autor:
David S. Grierson, Carter Tesch, Joseph Kern, Dileep Singh, Valentin Pauly, Kumar Sridharan, Malcolm Clark, Oyelayo O. Ajayi
Publikováno v:
Journal of Nuclear Materials. 522:311-323
Incoloy 800HT and Inconel 617 have been selected as candidate structural alloys for the high-temperature gas-cooled reactor (HTGR) concept. Helium, the primary coolant, contains impurities (e.g., H2O and CH4) that can induce corrosion reactions at hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f47d0db0bba11b64ec751a3d96d4168
https://doi.org/10.1016/j.jnucmat.2019.05.025
https://doi.org/10.1016/j.jnucmat.2019.05.025
Autor:
David S. Grierson, Sara Hosseini Farahabadi, Alireza Baradaran-Heravi, Alexandra Krause, Michel Roberge, Safwat M. Rabea, Aruna D. Balgi
Publikováno v:
ACS Med Chem Lett
[Image: see text] Nonsense mutations introduce a premature termination codon (PTC) and are the underlying cause of multiple rare genetic diseases and cancers. Although certain aminoglycosides bind to eukaryotic ribosomes enabling incorporation of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b341b5a9fd618a3a06c29fbfbf06ae8
https://doi.org/10.1021/acsmedchemlett.8b00610
https://doi.org/10.1021/acsmedchemlett.8b00610
Publikováno v:
Synthesis. 51:1779-1790
The S-benzyl thioester and methyl ester derivatives of a representative 4-pyridinone-based carboxylic acid were sufficiently activated to react efficiently in amide coupling reactions with the amide anion generated in situ from the N-trimethylsilyl d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62e6e6a303ba0086eb5e8bdda3167ebe
https://doi.org/10.1055/s-0037-1611435
https://doi.org/10.1055/s-0037-1611435
Autor:
Cunjie Chang, Muthukumar Rajasekaran, Yiting Qiao, Heng Dong, Yu Wang, Hongping Xia, Amudha Deivasigamani, Minjie Wu, Karthik Sekar, Hengjun Gao, Mengqing Sun, Yuqin Niu, Qian Li, Lin Tao, Zhen Yan, Menglan Wang, Shasha Chen, Shujuan Zhao, Dajing Chen, Lina Li, Fan Yang, Haojin Gao, Baodong Chen, Ling Su, Liang Xu, Ye Chen, Veerabrahma Pratap Seshachalam, Gongxing Chen, Jayantha Gunaratne, Wanjin Hong, Junping Shi, Gongying Chen, David S. Grierson, Benoit Chabot, Tian Xie, Kam Man Hui, Jianxiang Chen
Publikováno v:
Nature communications. 13(1)
Deregulation of alternative splicing is implicated as a relevant source of molecular heterogeneity in cancer. However, the targets and intrinsic mechanisms of splicing in hepatocarcinogenesis are largely unknown. Here, we report a functional impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d630daab5d7e27c76b3d89a6b3389c
https://pubmed.ncbi.nlm.nih.gov/35296659
https://pubmed.ncbi.nlm.nih.gov/35296659
Autor:
David S. Grierson, Christophe Combet, Thomas Lahlali, Lee D. Arnold, Héloïse Auclair, Caroline Pons, Julie Lucifora, Yohann Couté, Uri Lopatin, David Durantel, Yujin Kim, Benoit Chabot, Anna Salvetti, Serena Vegna, Hélène Chabrolles, Ariel Di Bernardo, Fabien Zoulim, Michel Rivoire, Pascal Jalaguier, Lucid Belmudes, Maud Michelet
Despite the existence of a preventive vaccine, chronic infection with Hepatitis B virus (HBV) affects more than 250 million people and represents a major global cause of hepatocellular carcinoma (HCC) worldwide. Current clinical treatments, in most o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f1953fdca6b4c9f486dfff444b08a2
https://doi.org/10.1101/2020.05.04.076646
https://doi.org/10.1101/2020.05.04.076646
Autor:
Chaiyapat Tangpatjaroen, Rafael A. Martínez, Izabela Szlufarska, Kushal Bagchi, David S. Grierson
Publikováno v:
The Journal of Physical Chemistry C. 122:27775-27781
Physical vapor deposition (PVD) with a slow deposition rate and substrate temperature near the glass transition temperature can produce glasses with exceptional properties that include higher density, lower enthalpy, and better kinetic stability than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::034ddabbc399fff3f2fae842b9753f01
https://doi.org/10.1021/acs.jpcc.8b09718
https://doi.org/10.1021/acs.jpcc.8b09718