Zobrazeno 1 - 10
of 58
pro vyhledávání: '"David S Lester"'
Publikováno v:
Fourier Transform Spectroscopy.
We have developed a new Fourier transform infrared chemical imaging technique1 which, when coupled with powerful multivariate data processing methods, allows the visualization of intrinsic chemical distributions in biological samples and other compos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e916bbf3f5182948253176242795e4a
https://doi.org/10.1364/fts.1997.fwa.1
https://doi.org/10.1364/fts.1997.fwa.1
Autor:
David S Lester
Publikováno v:
Personalized medicine. 6(5)
Personalized medicine is recognized as being a significant part of the solution for providing better healthcare outcomes. However, there are multiple challenges to its adoption from many healthcare stakeholders. The challenges are not technological,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2296cff020e90f0e5ebea1d886e6ae6
https://pubmed.ncbi.nlm.nih.gov/29783307
https://pubmed.ncbi.nlm.nih.gov/29783307
Autor:
J. H. Connor, S. L. Senft, Daniel L. Alkon, J. A. Johnston, David S. Lester, James L. Olds, Donna L. McPhie
Publikováno v:
The Biological bulletin. 183(2)
The introduction of isolated genes or recombinant DNA into cultured cells is a key procedure in cell and molecular biological research. At present there are many methods for gene transfer. All of these methods have certain shortcomings. Most of them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2f98b05f6f971a7878ecca3108397f
https://pubmed.ncbi.nlm.nih.gov/29300655
https://pubmed.ncbi.nlm.nih.gov/29300655
Autor:
William Slikker, Larry C. Schmued, Frank D. Sistare, Neil E. Grunberg, Hilton Davis, David S. Lester, Joseph P. Hanig, Andrew C. Scallet, P. S. Pine, Patrick J. Faustino
Publikováno v:
Toxicological Sciences. 81:364-370
Ketamine is a widely used pediatric anesthetic recently reported (C. Ikonomidou et al., 1999, Science 283, 70-74) to enhance neuronal death in neonatal rats. To confirm and extend these results, we treated four groups of PND 7 rats with seven sc dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d51477cb42b9234f329d2d57130bbb
https://doi.org/10.1093/toxsci/kfh224
https://doi.org/10.1093/toxsci/kfh224
Autor:
Shigenori Kawahara, J. de Barry, Agnes Janoshazi, James L. Olds, Ko-Ichi Takamura, Yutaka Kirino, David S. Lester, Daniel L. Alkon, Tohru Yoshioka
Publikováno v:
Experimental Cell Research. 234:115-124
To study protein kinase C (PKC) activation during sea urchin egg fertilization we used three different fluorescent probes specific for PKC, namely, fim-1, which recognizes the catalytic site of the enzyme, and BODIPY- and NBD-phorbol esters interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d69a681761543d6d5acbde1f630649
https://doi.org/10.1006/excr.1997.3597
https://doi.org/10.1006/excr.1997.3597
Autor:
Victor F. Kalasinsky, David S. Lester, E. Neil Lewis, Joseph P. Hanig, Linda H. Kidder, Ira W. Levin
Publikováno v:
Annals of the New York Academy of Sciences. 820:234-247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664ed7ffef631b9d37fe9d52f6f769d7
https://doi.org/10.1111/j.1749-6632.1997.tb46199.x
https://doi.org/10.1111/j.1749-6632.1997.tb46199.x
Autor:
William J. Freed, David S. Lester, Henrietta Kulaga, Robert S. Lebovics, Jasna Basaric-Keys, Trey Sunderland, Benjamin Wolozin, Yunhua Li, K. Peter Lesch, Marquis P. Vawter
Publikováno v:
Experimental Neurology. 142:179-194
Olfactory neuroepithelial cells (ONC) grown from biopsies of human donors are a novel cell culture system that may facilitate studies into normal and disease-related human neurobiology. We further characterized the expression of cell surface markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21af0e8974bfee8b65b55442873f8cf3
https://doi.org/10.1006/exnr.1996.0189
https://doi.org/10.1006/exnr.1996.0189
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1291:167-176
The present study examines the synergistic activation of PKC by arachidonic acid and diacylglycerols in phospholipid vesicles and demonstrates that this combination of activators leads to the formation of a constitutively active, phospholipid-bound f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f936ea5c006ca8bbed6a42aa1342f7e
https://doi.org/10.1016/0304-4165(96)00063-3
https://doi.org/10.1016/0304-4165(96)00063-3
Autor:
Bernard G. Schreurs, David S. Lester
Publikováno v:
Brain Research. 730:125-132
In the present study, we extend previous research on staining of living brain slices with fluorescent phospholipids. This new procedure allows high-resolution staining of specific cell types, in particular, Purkinje cells, in the cerebellar slice whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841e30be1bed843ea64526ed87f363bb
https://doi.org/10.1016/0006-8993(96)00439-8
https://doi.org/10.1016/0006-8993(96)00439-8
Autor:
Joshua Baru, Jean de Barry, Daniel L. Alkon, James L. Olds, Adam Gerstein, Giorgio A. Ascoli, Lisa Cameron, Zachary Freyberg, Terese L. Rakow, Tohru Yoshioka, Antonella Favit, David S. Lester, Mark Cameron, Thomas J. Nelson
Publikováno v:
Developmental Biology. 172(2):675-682
The fluorescent dye NBD–phorbol acetate was used to visualize the activation of protein kinase C (PKC) in livingLytechinus pictuseggs during fertilization. This dye interacts directly with PKC as determined using a competitive binding assay. Quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa4538cfacfdb4b5ef2436354371f25