Zobrazeno 1 - 10
of 141
pro vyhledávání: '"David S Guttery"'
Autor:
Mohammad Zeeshan, Edward Rea, Steven Abel, Kruno Vukušić, Robert Markus, Declan Brady, Antonius Eze, Ravish Rashpa, Aurelia C. Balestra, Andrew R. Bottrill, Mathieu Brochet, David S. Guttery, Iva M. Tolić, Anthony A. Holder, Karine G. Le Roch, Eelco C. Tromer, Rita Tewari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The Aurora family of kinases orchestrates chromosome segregation and cytokinesis during cell division, with precise spatiotemporal regulation of its catalytic activities by distinct protein scaffolds. Plasmodium spp., the causative agents of
Externí odkaz:
https://doaj.org/article/b48dddf02dd94fbda52d44cd32baa0e1
Autor:
Mohammad Zeeshan, Rajan Pandey, Amit Kumar Subudhi, David J. P. Ferguson, Gursimran Kaur, Ravish Rashpa, Raushan Nugmanova, Declan Brady, Andrew R. Bottrill, Sue Vaughan, Mathieu Brochet, Mathieu Bollen, Arnab Pain, Anthony A. Holder, David S. Guttery, Rita Tewari
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Zeeshan et al. used real-time live-cell and ultrastructural imaging, conditional gene knockdown, RNA-seq and proteomic approaches to implicate Plasmodium PP1 in both mitotic exit and, potentially, establishing cell polarity during zygote development
Externí odkaz:
https://doaj.org/article/b7773fc630264f8886ca813289e58978
Autor:
Christopher S. Trethewey, Harriet S. Walter, Abdullah N. M. Alqahtani, Ralf Schmid, David S. Guttery, Yvette Griffin, Matthew J. Ahearne, Gerald S. Saldanha, Sandrine P. N. Jayne, Martin J. S. Dyer
Publikováno v:
HemaSphere, Vol 6, Iss 3, p e690 (2022)
Externí odkaz:
https://doaj.org/article/967ccda3ab2f4e9ab9d08f2e07306d19
Autor:
Daniel Fernandez-Garcia, Allison Hills, Karen Page, Robert K. Hastings, Bradley Toghill, Kate S. Goddard, Charlotte Ion, Olivia Ogle, Anna Rita Boydell, Kelly Gleason, Mark Rutherford, Adrian Lim, David S. Guttery, R. Charles Coombes, Jacqueline A. Shaw
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background Breast cancer (BC) is the most common cancer in women, and despite the introduction of new screening programmes, therapies and monitoring technologies, there is still a need to develop more useful tests for monitoring treatment re
Externí odkaz:
https://doaj.org/article/87504f0fda684de3a025d675f61fdfdf
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111367- (2021)
Background: Metabolic syndrome (MS) is a major global health concern comprising a cluster of co-occurring conditions that increase the risk of heart disease, stroke and type 2 diabetes. MS is usually diagnosed using a combination of physiochemical in
Externí odkaz:
https://doaj.org/article/eeecafc2c282468ca70e9d095ae15e63
Autor:
Konstantinos Polymeros, David S Guttery, Roger Hew, Rachael Bishop, Elizabeth Stannard, Salvador Macip, Paul Symonds, Esther L Moss
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233900 (2020)
ObjectivesTo identify differences in the mutational profile of endometrial tumours between British White (BW) and South Asian (BSA) women.MethodsWe analysed primary tumours from matched cohorts of British White (BW) and British South Asian (BSA) wome
Externí odkaz:
https://doaj.org/article/734ecce134644f18a7a33e329bd4102a
Publikováno v:
Biology, Vol 11, Iss 1, p 134 (2022)
As an important imaging modality, mammography is considered to be the global gold standard for early detection of breast cancer. Computer-Aided (CAD) systems have played a crucial role in facilitating quicker diagnostic procedures, which otherwise co
Externí odkaz:
https://doaj.org/article/e23c8d825fef4d5895e608c87a339e91
Autor:
Richard J. Wall, David J. P. Ferguson, Aline Freville, Blandine Franke-Fayard, Declan Brady, Mohammad Zeeshan, Andrew R. Bottrill, Sally Wheatley, Andrew M. Fry, Chris J. Janse, Hiroyuki Yamano, Anthony A. Holder, David S. Guttery, Rita Tewari
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract The anaphase promoting complex/cyclosome (APC/C) is a highly conserved multi-subunit E3 ubiquitin ligase that controls mitotic division in eukaryotic cells by tagging cell cycle regulators for proteolysis. APC3 is a key component that contri
Externí odkaz:
https://doaj.org/article/c4146aca53b342b192bb9f54c10c319c
Autor:
Shui-Hua Wang, Shipeng Xie, Xianqing Chen, David S. Guttery, Chaosheng Tang, Junding Sun, Yu-Dong Zhang
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Aim: This paper proposes a novel alcoholism identification approach that can assist radiologists in patient diagnosis.Method: AlexNet was used as the basic transfer learning model. The global learning rate was small, at 10−4, and the iteration epoc
Externí odkaz:
https://doaj.org/article/c6581fdce95f4fe5b7bb0e04ac093067
Autor:
Magali Roques, Rebecca R. Stanway, Edward I. Rea, Robert Markus, Declan Brady, Anthony A. Holder, David S. Guttery, Rita Tewari
Publikováno v:
Biology Open, Vol 8, Iss 1 (2019)
Centrins are calmodulin-like phosphoproteins present in the centrosome and play an active role in the duplication, separation and organization of centrosomal structures such as the microtubule-organizing centre (MTOC) during mitosis. They are also ma
Externí odkaz:
https://doaj.org/article/13bfe521fe604846bc8b9b755282a6ff