Zobrazeno 1 - 10
of 59
pro vyhledávání: '"David S Grass"'
Autor:
Leonard D. Shultz, David S Grass, Cathleen Lutz, Nadia Rosenthal, Stephen A. Murray, Edison T. Liu, Ewelina Bolcun-Filas
Publikováno v:
EMBO Reports
The usefulness of a specific technology often hits a ceiling based on technical limitations. Then, a single advance, frequently orthogonal to the core methodology, dramatically expands the utility of this technology. The effectiveness of early surgeo
Publikováno v:
Cancer Research. 78:5111-5111
Mouse models continue to be powerful tools in preclinical oncology and immuno-oncology studies. The development of the inbred highly immunocompromised mouse strain NSG (NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ) has dramatically improved the ability to work wi
Autor:
Arne Dikkers, Birgitta Rosengren, Thomas Gautier, Uwe J. F. Tietge, Eva Hurt-Camejo, Daniel J. Rader, Margareta Behrendt, David S. Grass
Publikováno v:
Arteriosclerosis thrombosis and vascular biology, 33(12), 2707-2714. LIPPINCOTT WILLIAMS & WILKINS
Objective— High circulating levels of group IIA secretory phospholipase A 2 (sPLA 2 -IIA) activity and mass are independent cardiovascular risk factors. Therefore, inhibition of sPLA 2 -IIA may be a target for the treatment of atherosclerotic cardi
Publikováno v:
Annals of the New York Academy of Sciences. 1245:27-30
Our approach has been to power studies to allow for detection of at least modest changes from a wild-type littermate control, include assays with overlapping physiological systems to provide cross-functional interpretive value, and to employ challeng
Publikováno v:
The Journal of Immunology. 200:178.34-178.34
The NSG (NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ) mouse strain is highly immunodeficient and has dramatically improved the ability to work with human tumors in an organismal context using xenograft approaches. Technical innovations have expanded the utility
Autor:
David S. Grass, Mark A. Cane
Publikováno v:
International Journal of Climatology. 28:1113-1126
This study quantifies the effects of stressful weather and elevated air pollution levels on cause-specific mortality in Santiago, Chile, during the austral winters from 1988 to 1996. A temporal synoptic index (TSI) is used to form weather classes and
Autor:
Ed Lim, Tony Purchio, Anne C Clermont, John J. Hunter, Scott K. Lyons, Joan Dusich, Kenneth D. Campbell, Darlene Jenkins, Lingyun Zhu, Richard Coffee, David S. Grass
Publikováno v:
Cancer Research. 66:4701-4707
Several transgenic mouse models of prostate cancer have been developed recently that are able to recapitulate many key biological features of the human condition. It would, therefore, be desirable to employ these models to test the efficacy of new th
Autor:
H. James Simpson, David L. Epstein, Sonja N. Sax, John D. Spengler, David Johnson, David S. Grass, Paul W. Brandt-Rauf, James Ross, Steven N. Chillrud, Patrick L. Kinney, Drissa Coulibaly, Dee Pederson, Vesna Slavkovich
Publikováno v:
Journal of Urban Health: Bulletin of the New York Academy of Medicine. 82:33-42
The United States Clean Air Act Amendments of 1990 reflected increasing concern about potential effects of low-level airborne metal exposure on a wide array of illnesses. Here we summarize results demonstrating that the New York City (NYC) subway sys
Autor:
Daniel J. Rader, David S. Grass, Frederick C. deBeer, Sissel Lund-Katz, Uwe J. F. Tietge, Cyrille Maugeais
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 22:1213-1218
Objective—Plasma levels of high density lipoprotein (HDL) cholesterol and apolipoprotein (apo)A-I are decreased in inflammatory states. Secretory phospholipase A2(sPLA2), an acute-phase protein, may play a key role in the pathophysiology of this ph
Publikováno v:
Electrophoresis. 21:2957-2968
We present a modification of mRNA differential display in which increased throughput results from the use of an automated fluorescent sequencer. The sequence analysis is performed directly on purified fragments without further cloning. The amplified