Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David Sánchez Hernández"'
Autor:
Eléanor Simon, Carlos Jiménez-Jiménez, Irene Seijo-Barandiarán, Gustavo Aguilar, David Sánchez-Hernández, Adrián Aguirre-Tamaral, Laura González-Méndez, Pedro Ripoll, Isabel Guerrero
Publikováno v:
eLife, Vol 10 (2021)
The conserved family of Hedgehog (Hh) signaling proteins plays a key role in cell–cell communication in development, tissue repair, and cancer progression, inducing distinct concentration-dependent responses in target cells located at short and lon
Externí odkaz:
https://doaj.org/article/e3c7dd49d59e45dc9996748a69366f07
Autor:
Ana Gradilla, David Sánchez-Hernández, Carlos Jiménez-Jiménez, Sheila Jordán-Álvarez, Adrián Aguirre-Tamaral, Irene Sánchez, James Wakefield, Isabel Guerrero
During Drosophila epithelial development, signalling specialized filopodial or cytonemes establish direct contacts between distant cells to facilitate the formation of the Hedgehog (Hh) signalling gradient. However, the regulatory mechanisms for Hh c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97144ad6d9711d4ef2cffb6d891c2dab
https://doi.org/10.21203/rs.3.rs-2513634/v1
https://doi.org/10.21203/rs.3.rs-2513634/v1
Autor:
Gustavo Aguilar, Pedro Ripoll, Irene Seijo-Barandiarán, Adrián Aguirre-Tamaral, Carlos Jiménez-Jiménez, Eléanor Simon, David Sánchez-Hernández, Laura González-Méndez, Isabel Guerrero
Publikováno v:
eLife
eLife, Vol 10 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife, Vol 10 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
The conserved family of Hedgehog (Hh) signaling proteins plays a key role in cell-cell communication during development, tissue repair and cancer progression, inducing distinct concentration-dependent responses in target cells located at short and lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd63017a14a0bc21d6118819d9d1d801
http://europepmc.org/articles/PMC8410076
http://europepmc.org/articles/PMC8410076
Autor:
Eléanor Simon, Irene Seijo-Barandiarán, Laura González-Méndez, Adrián Aguirre-Tamaral, Pedro Ripoll, Isabel Guerrero, David Sánchez-Hernández, Gustavo Aguilar, Carlos Jiménez-Jiménez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565bbeb3455cccb27465327c6d9bab54
https://doi.org/10.7554/elife.64581.sa2
https://doi.org/10.7554/elife.64581.sa2
Autor:
Pedro Ripoll, Irene Seijo-Barandiarán, Adrián Aguirre-Tamaral, Eléanor Simon, David Sánchez-Hernández, Laura González-Méndez, Carlos Jiménez-Jiménez, Isabel Guerrero, Gustavo Aguilar
The conserved family of Hedgehog (Hh) signaling proteins plays a key role in cell-cell communication in development, tissue repair and cancer progression. These proteins can act as morphogens, inducing responses dependent on the ligand concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28abe46e6436bc2fe0d29fe0e357a3c3
https://doi.org/10.1101/2020.11.04.367797
https://doi.org/10.1101/2020.11.04.367797
Autor:
Isabel Guerrero, Carlos Jiménez-Jiménez, Milagros Guerra, Juan M. Falcón-Pérez, Laura González-Méndez, Esperanza Gonzalez, Ana-Citlali Gradilla, David Sánchez-Hernández, Gustavo Aguilar, Germán Andrés, Adrián Aguirre-Tamaral
Publikováno v:
EMBO J
Hedgehog (Hh) signal molecules play a fundamental role in development, adult stem cell maintenance and cancer. Hh can signal at a distance, and we have proposed that its graded distribution across Drosophila epithelia is mediated by filopodia-like st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63da6c5fc760d6fd8f4ba1de7120f753
https://doi.org/10.15252/embj.2019103629
https://doi.org/10.15252/embj.2019103629
Publikováno v:
openAccess
Digital.CSIC. Repositorio Institucional del CSIC
instname
BMC Biology
BMC Biology, Vol 16, Iss 1, Pp 1-11 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
BMC Biology
BMC Biology, Vol 16, Iss 1, Pp 1-11 (2018)
Spatial organization of membrane domains within cells and cells within tissues is key to the development of organisms and the maintenance of adult tissue. Cell polarization is crucial for correct cell–cell signalling, which, in turn, promotes cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc1207cb71776022a478100455e211a
http://hdl.handle.net/10261/163631
http://hdl.handle.net/10261/163631
Autor:
Ainhoa Callejo, Emanuela Mollica, Isabel Guerrero, M. Carmen Rodríguez-Navas, Eléanor Simon, Aphrodite Bilioni, Ana-Citlali Gradilla, David Sánchez-Hernández, Carmen Ibañez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Hedgehog can signal both at a short and long-range, and acts as a morphogen during development in various systems. We studied the mechanisms of Hh release and spread using the Drosophila wing imaginal disc as a model system for polarized epithelium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff15bb1b87b92a7079e44ccdc40c988e
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The Hedgehog (Hh) and Wnt signaling pathways are crucial for development as well as for adult stem cell maintenance in all organisms from Drosophila to humans. Aberrant activation of these pathways has been implicated in many types of human cancer. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c25b149ced82f8e3d319bb704f3d1dd
https://doi.org/10.1242/dev.104653
https://doi.org/10.1242/dev.104653