Zobrazeno 1 - 10
of 557
pro vyhledávání: '"David S, Warner"'
Autor:
Xuan Li, Weina Duan, Li Du, Dongmei Chu, Peng Wang, Zhong Yang, Xingguang Qu, Zhenxing Yang, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, James D. Crapo, Miriam M. Treggiari, Huaxin Sheng
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1861 (2023)
Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor outcomes. Manganese porphyri
Externí odkaz:
https://doaj.org/article/cd7bd498d53b459a86835b675ccfbd52
Autor:
Wei Wang, Ran Li, Wanying Miao, Cody Evans, Liping Lu, Jingjun Lyu, Xuan Li, David S. Warner, Xiaoping Zhong, Ulrike Hoffmann, Huaxin Sheng, Wei Yang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 11 (2021)
Background Animal disease models represent the cornerstone in basic cardiac arrest (CA) research. However, current experimental models of CA and resuscitation in mice are limited. In this study, we aimed to develop a mouse model of asphyxial CA follo
Externí odkaz:
https://doaj.org/article/e9649b049f5440bd9734e13b11d309c7
Autor:
Peng Wang, Ying Li, Baihui Yan, Zhong Yang, Litao Li, Zhipeng Cao, Xuan Li, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, Huaxin Sheng
Publikováno v:
Biology, Vol 11, Iss 7, p 957 (2022)
Introduction Cardiac arrest (CA) and resuscitation induces global cerebral ischemia and reperfusion, causing neurologic deficits or death. Manganese porphyrins, superoxide dismutase mimics, are reportedly able to effectively reduce ischemic injury in
Externí odkaz:
https://doaj.org/article/d4801eb592674fea9a873bfe3ebe760a
Autor:
Weina Duan, Qian Sun, Xiaojing Wu, Zhongyuan Xia, David S. Warner, Luis Ulloa, Wei Yang, Huaxin Sheng
Publikováno v:
Neuromodulation: Technology at the Neural Interface. 25:414-423
Cerebral ischemia and reperfusion (I/R) induces oxidative stress and activates autophagy, leading to brain injury and neurologic deficits. Cervical vagus nerve stimulation (VNS) increases cerebral blood flow (CBF). In this study, we investigate the e
Autor:
Litao Li, Artak Tovmasyan, Huaxin Sheng, Bin Xu, Romulo S. Sampaio, Julio S. Reboucas, David S. Warner, Ines Batinic-Haberle, Ivan Spasojevic
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 467 (2020)
Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, (H2O)MnTnHex-2-PyP5+ (MnHex) carrying long hexyl chains, is a lipophilic mimic of superoxide dismutase (SOD) and a redox-active drug candidate. MnHex crosses the blood–brain barrier, and imp
Externí odkaz:
https://doaj.org/article/d83788040c914f609e0dafa1e226aa0f
Autor:
David S, Warner, Michael M, Todd
Publikováno v:
Anesthesiology. 136:176-180
David Warner, M.D., and Michael Todd, M.D., first met in 1985. They began working together at the University of Iowa (Iowa City, Iowa) a year later with a shared interest in both laboratory and clinical neuroscience—and in the operative care of neu
Autor:
Dongmei Chu, Xuan Li, Xingguang Qu, Deepti Diwan, David S. Warner, Gregory J. Zipfel, Huaxin Sheng
Publikováno v:
Neurocritical Care.
An increase in sirtuin 1 (SIRT1) reportedly attenuates early brain injury, delayed cerebral ischemia, and short-term neurologic deficits in rodent models of subarachnoid hemorrhage (SAH). This study investigates the effect of resveratrol, a SIRT1 act
Autor:
Gavin D. Perkins, Steve Beerman, J. Seesink, Theresa M. Olasveengen, S. Johnson, Justin Sempsrott, H.E. Elsenga, P. Morgan, J.C. Pereira, Andrew Schmidt, Jonathon Webber, Cristian Abelairas-Gómez, R. Barcala Furelos, Joost J.L.M. Bierens, David Szpilman, Tom Stefan Mecrow, David S. Warner, Andrea Scapigliati, Peter T. Morley, Cody Dunne, Andreas Claesson
Publikováno v:
Resuscitation. 162:205-217
Background The ILCOR Basic Life Support Task Force and the international drowning research community considered it timely to undertake a scoping review of the literature to identify evidence relating to the initial resuscitation, hospital-based inter
Sex Differences from in Vivo Single Microglial Cell Isolation after Intracerebral Hemorrhage in Mice
Autor:
Beilei Lei, Yong Ho Kim, Wenjing Qi, Temugin Berta, Anna Covington, Jay Lusk, David S. Warner, Michael L. James
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Brain research bulletin. 183
Ischemic stroke in rodents is usually induced by intraluminal occlusion of the middle cerebral artery (MCA) via the external carotid artery (ECA) or the common carotid artery (CCA). The latter route requires permanent CCA occlusion after ischemia, an