Zobrazeno 1 - 10 of 381 pro vyhledávání: '"David S, Salomon"'
1
Akademický článek
Different pancreatic cancer microenvironments convert iPSCs into cancer stem cells exhibiting distinct plasticity with altered gene expression of metabolic pathways
Autor: Ghmkin Hassan, Toshiaki Ohara, Said M. Afify, Kazuki Kumon, Maram H. Zahra, Xiaoying Fu, Mohamad Al Kadi, Akimasa Seno, David S. Salomon, Masaharu Seno
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cancer stem cells (CSCs) are generated under irregular microenvironment in vivo, of which mimic is quite difficult due to the lack of enough information of the factors responsible for cancer initiation. Here, we demonstrated that
Externí odkaz: https://doaj.org/article/daf6adf4317e48ca892776e146be0047
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2
GSK-3α/β and MEK inhibitors assist the microenvironment of tumor initiation
Autor: Ghmkin Hassan, Said M. Afify, Maram H. Zahra, Hend M. Nawara, Kazuki Kumon, Yoshiaki Iwasaki, David S. Salomon, Akimasa Seno, Masaharu Seno
Publikováno v: Cytotechnology. 75:243-253
Induced pluripotent stem cells (iPSCs) are useful tools for modeling diseases and developing personalized medicine. We have been developing cancer stem cells (CSCs) from iPSCs with conditioned medium (CM) of cancer-derived cells as the mimicry of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ff36a9153d9a8c660271ca46a223204
https://doi.org/10.1007/s10616-023-00575-1
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4
Data from Sulforaphane Suppresses the Growth of Triple-negative Breast Cancer Stem-like Cells In vitro and In vivo
Autor: Young S. Kim, David S. Salomon, Frank Cuttitta, Gabriel MacKinnon, Anand S. Merchant, Maria C. Rangel, Nadia P. Castro
Triple-negative breast cancer (TNBC) represents the poorest prognosis among all of breast cancer subtypes with no currently available effective therapy. In this study, we hypothesized that sulforaphane, a dietary component abundant in broccoli and it
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9abbed734332012fabeeed7eefbc5940
https://doi.org/10.1158/1940-6207.c.6547318.v1
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7
Akademický článek
Adaptation of Laser Microdissection Technique for the Study of a Spontaneous Metastatic Mammary Carcinoma Mouse Model by NanoString Technologies.
Autor: Nadia P Castro, Anand S Merchant, Karen L Saylor, Miriam R Anver, David S Salomon, Yelena G Golubeva
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153270 (2016)
Laser capture microdissection (LCM) of tissue is an established tool in medical research for collection of distinguished cell populations under direct microscopic visualization for molecular analysis. LCM samples have been successfully analyzed in a
Externí odkaz: https://doaj.org/article/7f0de28f3d634b068b273042eccbbe1e
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8
TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer
Autor: David Peeney, Silvia Noonan, William G. Stetler-Stevenson, Joanna Shih, Sandra M. Jensen, David S. Salomon, Nadia P. Castro, Sarvesh Kumar, Chenchen Handler, Andy D Tran, Alex Kuznetsov
Publikováno v: Carcinogenesis
Metastasis is the primary cause of treatment failures and mortality in most cancers. Triple-negative breast cancer (TNBC) is refractory to treatment and rapidly progresses to disseminated disease. We utilized an orthotopic mouse model that molecularl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d8d73dd0ff0ace096112a69c48655f
https://doi.org/10.1093/carcin/bgz172
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9
Sulforaphane Suppresses the Growth of Triple-negative Breast Cancer Stem-like Cells In vitro and In vivo
Autor: Maria Cristina Rangel, Nadia P. Castro, Gabriel M MacKinnon, David S. Salomon, Young Sik Kim, Frank Cuttitta, Anand S. Merchant
Publikováno v: Cancer Prevention Research. 12:147-158
Triple-negative breast cancer (TNBC) represents the poorest prognosis among all of breast cancer subtypes with no currently available effective therapy. In this study, we hypothesized that sulforaphane, a dietary component abundant in broccoli and it
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::667388cf415f2d84c89d73235bbc133c
https://doi.org/10.1158/1940-6207.capr-18-0241
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10
Akademický článek
Efficient drug delivery of Paclitaxel glycoside: a novel solubility gradient encapsulation into liposomes coupled with immunoliposomes preparation.
Autor: Tsukasa Shigehiro, Tomonari Kasai, Masaharu Murakami, Sreeja C Sekhar, Yuki Tominaga, Masashi Okada, Takayuki Kudoh, Akifumi Mizutani, Hiroshi Murakami, David S Salomon, Katsuhiko Mikuni, Tadakatsu Mandai, Hiroki Hamada, Masaharu Seno
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e107976 (2014)
Although the encapsulation of paclitaxel into liposomes has been extensively studied, its significant hydrophobic and uncharged character has generated substantial difficulties concerning its efficient encapsulation into the inner water core of lipos
Externí odkaz: https://doaj.org/article/9d70f1e49e4445e788735539da75532b
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