Zobrazeno 1 - 10
of 40
pro vyhledávání: '"David S, Gibson"'
Publikováno v:
Experimental and Molecular Pathology, Vol 139, Iss , Pp 104924- (2024)
Aims: Phytocannabinoids and terpenes from Cannabis sativa have demonstrated limited anti-inflammatory and analgesic effects in several inflammatory conditions. In the current study, we test the hypothesis that phytocannabinoids exert immunomodulatory
Externí odkaz:
https://doaj.org/article/b6081e8f12d84c52abba9e1d3ac4a300
Autor:
Andrew English, Darren McDaid, Seodhna M Lynch, Joseph McLaughlin, Eamonn Cooper, Benjamin Wingfield, Martin Kelly, Manav Bhavsar, Victoria McGilligan, Rachelle E Irwin, Magda Bucholc, Shu-Dong Zhang, Priyank Shukla, Taranjit Singh Rai, Anthony J Bjourson, Elaine Murray, David S Gibson, Colum Walsh
Publikováno v:
JMIR Research Protocols, Vol 13, p e50733 (2024)
BackgroundHealth organizations and countries around the world have found it difficult to control the spread of COVID-19. To minimize the future impact on the UK National Health Service and improve patient care, there is a pressing need to identify in
Externí odkaz:
https://doaj.org/article/9d3aa112b7c648fa98385798283fb59c
Autor:
Michelle K. Greene, Peter Smyth, Andrew English, Joseph McLaughlin, Magda Bucholc, Janice Bailie, Julie McCarroll, Margaret McDonnell, Alison Watt, George Barnes, Mark Lynch, Kevan Duffin, Gerard Duffy, Claire Lewis, Jacqueline A. James, Alan W. Stitt, Tom Ford, Maurice O'Kane, Taranjit Singh Rai, Anthony J. Bjourson, Christopher Cardwell, J Stuart Elborn, David S. Gibson, Christopher J. Scott
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24184- (2024)
Background: With the spread of SARS-CoV-2 impacting upon public health directly and socioeconomically, further information was required to inform policy decisions designed to limit virus spread during the pandemic. This study sought to contribute to
Externí odkaz:
https://doaj.org/article/7d4d4ec7cbc4481399abfb0592ef4565
Autor:
Katie L. Druce, David S. Gibson, Kevin McEleney, Belay B. Yimer, Stephanie Meleck, Ben James, Bruce Hellman, William G. Dixon, John McBeth
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background People with rheumatic diseases experience troublesome fluctuations in fatigue. Debated causes include pain, mood and inflammation. To determine the relationships between these potential causes, serial assessments are required but
Externí odkaz:
https://doaj.org/article/22963c0a0a0e4a1089762092fe543bdd
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 12, p 1633 (2023)
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that has a significant impact on quality of life and work capacity. Treatment of RA aims to control inflammation and alleviate pain; however, achieving remission with minimal toxicity is freq
Externí odkaz:
https://doaj.org/article/ee8878aba1ae4cb8960561eccecbc27e
Autor:
Bodhayan Prasad, Cathy McGeough, Amanda Eakin, Tan Ahmed, Dawn Small, Philip Gardiner, Adrian Pendleton, Gary Wright, Anthony J Bjourson, David S Gibson, Priyank Shukla
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010204 (2022)
Rheumatoid arthritis (RA) is a chronic autoimmune condition, characterised by joint pain, damage and disability, which can be addressed in a high proportion of patients by timely use of targeted biologic treatments. However, the patients, non-respons
Externí odkaz:
https://doaj.org/article/e68e0c9a41ea4c968ea5ed183bee795d
Autor:
Amanda J. Eakin, Tahanver Ahmed, Cathy M. McGeough, Stephen Drain, H. Denis Alexander, Gary D. Wright, Philip V. Gardiner, Dawn Small, Anthony J. Bjourson, David S. Gibson
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 11, p 1875 (2022)
Disease activity in rheumatoid arthritis (RA) is influenced by activation of circulating and synovial immune cells. Regulatory T cells (Tregs) and monocytes are key cells that drive inflammation in RA. This study investigated if a relationship exists
Externí odkaz:
https://doaj.org/article/80650ee054a4444db440e7ddd35fef13
Publikováno v:
Cells, Vol 10, Iss 12, p 3367 (2021)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial morbidity and mortality worldwide, with particular risk for severe disease and
Externí odkaz:
https://doaj.org/article/5419aad29d2646f582a6a47016d21c7b
Publikováno v:
Sensors, Vol 21, Iss 14, p 4688 (2021)
In the last decade, there has been a significant increase in the number of people diagnosed with dementia. With diminishing public health and social care resources, there is substantial need for assistive technology-based devices that support indepen
Externí odkaz:
https://doaj.org/article/b2866b30480a4d70bfe0abf768d873ed
Autor:
Antonella Fioravanti, Sara Tenti, Megan McAllister, Melody Chemaly, Amanda Eakin, Joseph McLaughlin, Anthony J. Bjourson, Elena Frati, Victoria McGilligan, Sara Cheleschi, David S. Gibson
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Hand osteoarthritis (HOA) includes different subsets; a particular and uncommon form is erosive HOA (EHOA). Interleukin- (IL-) 1β plays a crucial role in the pathogenesis of osteoarthritis (OA); it is synthesized as an inactive precursor which requi
Externí odkaz:
https://doaj.org/article/f269966889be4cfd972273e6f0aa9dd8