Zobrazeno 1 - 10
of 47
pro vyhledávání: '"David S, Garlick"'
Autor:
Jae Ho Seo, Ekta Agarwal, Young Chan Chae, Yu Geon Lee, David S. Garlick, Alessandra Maria Storaci, Stefano Ferrero, Gabriella Gaudioso, Umberto Gianelli, Valentina Vaira, Dario C. Altieri
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 353-363 (2019)
Background: Mitochondrial functions are exploited in cancer and provide a validated therapeutic target. However, how this process is regulated has remained mostly elusive and the identification of new pathways that control mitochondrial integrity in
Externí odkaz:
https://doaj.org/article/0a9731d7d93844228028cc2aca2b18d9
Autor:
Dario C. Altieri, Tung-Tien Sun, Xue-Ru Wu, Robert M. Weiss, David S. Garlick, Janet Plescia, Dan Eisenberg, Whitney Salz
Gene signatures that predict aggressive tumor behavior at the earliest stages of disease, ideally before overt tissue abnormalities, are urgently needed. To search for such genes, we generated a transgenic model of survivin, an essential regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5253980f09444f0fc6ba3e7b567325e0
https://doi.org/10.1158/0008-5472.c.6494442
https://doi.org/10.1158/0008-5472.c.6494442
Autor:
Dario C. Altieri, Tung-Tien Sun, Xue-Ru Wu, Robert M. Weiss, David S. Garlick, Janet Plescia, Dan Eisenberg, Whitney Salz
Supplementary Table 2 from A Survivin Gene Signature Predicts Aggressive Tumor Behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b973b5592a037a03c71aa0b8957ee1ed
https://doi.org/10.1158/0008-5472.22364937.v1
https://doi.org/10.1158/0008-5472.22364937.v1
Autor:
Roger J. Davis, Arthur M. Mercurio, David S. Garlick, Shaolei Lu, Julie Cavanagh-Kyros, Feng Jiang, Nomeda Girnius, Cristina Cellurale
PDF file - 379K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90018190461cfd3237c300923fb4c694
https://doi.org/10.1158/0008-5472.22393167
https://doi.org/10.1158/0008-5472.22393167
Autor:
Dario C. Altieri, Tung-Tien Sun, Xue-Ru Wu, Robert M. Weiss, David S. Garlick, Janet Plescia, Dan Eisenberg, Whitney Salz
Supplementary Table 1 from A Survivin Gene Signature Predicts Aggressive Tumor Behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2849a243d1ab3dff0289c79855d9771b
https://doi.org/10.1158/0008-5472.22364940.v1
https://doi.org/10.1158/0008-5472.22364940.v1
Autor:
Dario C. Altieri, Silvano Bosari, Joseph L. Kissil, Mario Nosotti, Stefano Ferrero, David S. Garlick, Nina M. Martin, Alice Faversani, Valentina Vaira
PDF File - 4789K, REGULATION OF LUNG CANCER METASTASIS BY Klf4-Numb-like SIGNALING.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ac16613d91708692c10c1e148f1622
https://doi.org/10.1158/0008-5472.22399251
https://doi.org/10.1158/0008-5472.22399251
Publikováno v:
eLife, Vol 7 (2018)
Breast cancer is the most commonly diagnosed malignancy in women. Analysis of breast cancer genomic DNA indicates frequent loss-of-function mutations in components of the cJUN NH2-terminal kinase (JNK) signaling pathway. Since JNK signaling can promo
Externí odkaz:
https://doaj.org/article/fe149e6f753d4c8e9afc0548b0fd5c6a
Autor:
Cristina Cellurale, Claire R Weston, Judith Reilly, David S Garlick, D Joseph Jerry, Hayla K Sluss, Roger J Davis
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12469 (2010)
The cJun NH2-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BAL
Externí odkaz:
https://doaj.org/article/e3edcc8710984e838f206fbeb95f0e60
Autor:
Valentina Vaira, Ekta Agarwal, Stefano Ferrero, Umberto Gianelli, Young Chan Chae, David S. Garlick, Yu Geon Lee, Gabriella Gaudioso, Dario C. Altieri, Alessandra Maria Storaci, Jae Ho Seo
Publikováno v:
EBioMedicine
Background Mitochondrial functions are exploited in cancer and provide a validated therapeutic target. However, how this process is regulated has remained mostly elusive and the identification of new pathways that control mitochondrial integrity in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f01b7c5721074affae4b33d3022d85
https://pubmed.ncbi.nlm.nih.gov/31542392
https://pubmed.ncbi.nlm.nih.gov/31542392
Autor:
Kathy Q. Cai, Matthew Jennis, Michelle R. Campbell, Qin Liu, Anna Budina-Kolomets, David S. Garlick, Donna L. George, Jeremy P. Scott, Subhasree Basu, Julia I-Ju Leu, Xiaoxian Li, Monica Hollstein, Devin K. Porter, Douglas A. Bell, Xuting Wang, Sakina Khaku, Maureen E. Murphy, Che-Pei Kung
Publikováno v:
Genes & Development. 30:918-930
A nonsynonymous single-nucleotide polymorphism at codon 47 in TP53 exists in African-descent populations (P47S, rs1800371; referred to here as S47). Here we report that, in human cell lines and a mouse model, the S47 variant exhibits a modest decreas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d368f574104c7e3ca578fc489b9465
https://doi.org/10.1101/gad.275891.115
https://doi.org/10.1101/gad.275891.115