Zobrazeno 1 - 10
of 17
pro vyhledávání: '"David Resina"'
Autor:
Marta Jarque, Alba Torija, Silvia Barcelo-Batllori, Laura de Ramon, David Resina, Nuria Bolaños, Oriol Bestard, Pere Fontova, Laura Martínez-Valenzuela, Josep M. Grinyó, Elena Crespo, Joan Torras, Jordi Guiteras
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1216, p 1216 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences
Volume 22
Issue 3
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences
Volume 22
Issue 3
Many studies have shown both the CD28&mdash
D80/86 costimulatory pathway and the PD-1&mdash
PD-L1/L2 coinhibitory pathway to be important signals in modulating or decreasing the inflammatory profile in ischemia-reperfusion injury (IRI) or i
D80/86 costimulatory pathway and the PD-1&mdash
PD-L1/L2 coinhibitory pathway to be important signals in modulating or decreasing the inflammatory profile in ischemia-reperfusion injury (IRI) or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe527e246bb8535ecd3a590f5e40595
https://www.mdpi.com/1422-0067/22/3/1216
https://www.mdpi.com/1422-0067/22/3/1216
Autor:
Ermenegilda Parrilli, Markku Saloheimo, Pau Ferrer, Wesley Smith, Maria Luisa Tutino, Felícitas Vázquez, Simó Schwartz, Maria Giuliani, Diethard Mattanovich, Brigitte Gasser, David Resina, Jussi Jäntti, Ibane Abasolo, José Luis Corchero, Antonio Villaverde
Publikováno v:
Europe PubMed Central
Corchero, J L, Gasser, B, Resina, D, Smith, W, Parrilli, E, Vázquez, F, Abasolo, I, Giuliani, M, Jäntti, J, Ferrer, P, Saloheimo, M, Mattanovich, D, Schwartz Jr., S, Tutino, M L & Villaverde, A 2013, ' Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics ', Biotechnology Advances, vol. 31, no. 2, pp. 140-153 . https://doi.org/10.1016/j.biotechadv.2012.09.001
Corchero, J L, Gasser, B, Resina, D, Smith, W, Parrilli, E, Vázquez, F, Abasolo, I, Giuliani, M, Jäntti, J, Ferrer, P, Saloheimo, M, Mattanovich, D, Schwartz Jr., S, Tutino, M L & Villaverde, A 2013, ' Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics ', Biotechnology Advances, vol. 31, no. 2, pp. 140-153 . https://doi.org/10.1016/j.biotechadv.2012.09.001
Both conventional and innovative biomedical approaches require cost-effective protein drugs with high therapeutic potency, improved bioavailability, biocompatibility, stability and pharmacokinetics. The growing longevity of the human population, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf8475848d58aec3701844e54f1a0d1
https://doi.org/10.1016/j.biotechadv.2012.09.001
https://doi.org/10.1016/j.biotechadv.2012.09.001
Publikováno v:
Recent Patents on Biotechnology. 3:192-201
Pichia pastoris is a widely used host system for heterologous protein expression both for basic research and industrial production purposes. Recent developments expanding the P. pastoris protein expression toolbox reflect the increasing interest in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636b43dcb968b3e00185ec0f22f39da2
https://doi.org/10.2174/187220809789389126
https://doi.org/10.2174/187220809789389126
Autor:
Carolina Arnau, Michael Maurer, David Resina, Oriol Cos, Hans Marx, Francisco Valero, Pau Ferrer, Marc Carnicer, Brigitte Gasser, Diethard Mattanovich
Publikováno v:
New Biotechnology. 25:396-403
The yeast Pichia pastoris has been previously used for extracellular expression of a Rhizopus oryzae lipase (Rol). However, limitations in Rol folding and secretion through the cell wall became apparent when producing it in fed-batch cultivations. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caac892ae44bc465123e247359830de0
https://doi.org/10.1016/j.nbt.2009.01.008
https://doi.org/10.1016/j.nbt.2009.01.008
Alternative production process strategies in E. coli improving protein quality and downstream yields
Autor:
Josep López-Santín, Gregorio Álvaro, Glòria González, Jaume Pinsach, Jordi Ruiz, Carles de Mas, David Resina
Publikováno v:
Process Biochemistry. 44:1039-1045
Process strategies for production of recombinant rhamnulose 1-phosphate aldolase (RhuA) in Escherichia coli were found to have an important impact on downstream processing when preparing the enzyme for its use as immobilized biocatalyst. First, a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58421d07e3fa765a0df4652e2776e9b8
https://doi.org/10.1016/j.procbio.2009.05.007
https://doi.org/10.1016/j.procbio.2009.05.007
Publikováno v:
Biochemical Engineering Journal. 26:86-94
A Rhizopus oryzae lipase (ROL) has been expressed in Pichia pastoris as a reporter gene using two different regulated promoters. Both phenotypes, Muts and Mut+, have been used for the expression under the control of alcohol oxidase 1 promoter (PAOX1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aed2cc25dc7ac7f4209b62b5f97e60c
https://doi.org/10.1016/j.bej.2005.04.005
https://doi.org/10.1016/j.bej.2005.04.005
Publikováno v:
Biotechnology and Bioengineering. 91:760-767
A Pichia pastoris strain expressing a Rhizopus oryzae lipase gene under the transcriptional control of the promoter from the P. pastoris formaldehyde dehydrogenase 1 gene (PFLD) was utilized to study the feasibility of this expression system for reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2301ec77f0490d9536352763040ad4
https://doi.org/10.1002/bit.20545
https://doi.org/10.1002/bit.20545
Publikováno v:
Journal of Biotechnology. 109:103-113
A Rhizopus oryzae lipase gene has been expressed in Pichia pastoris as a reporter using the formaldehyde dehydrogenase 1 promoter (PFLD1) of this organism, which has been reported to be strongly and independently induced by either methanol as sole ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cdbbcb6351c543c2fbbbf9172342bf
https://doi.org/10.1016/j.jbiotec.2003.10.029
https://doi.org/10.1016/j.jbiotec.2003.10.029
Publikováno v:
Microbial Cell Factories, Vol 6, Iss 1, p 15 (2007)
Microbial Cell Factories
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Microbial Cell Factories
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Background Together with the development of optical sensors, fluorometry is becoming an increasingly attractive tool for the monitoring of cultivation processes. In this context, the green fluorescence protein (GFP) has been proposed as a molecular r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042376118cd435d3483f7df7a79879bf
http://www.microbialcellfactories.com/content/6/1/15
http://www.microbialcellfactories.com/content/6/1/15
Autor:
Peter Neubauer, David Resina, Francisco Valero, Pau Ferrer, Narendar K. Khatri, Monika Bollok
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Microbial Cell Factories
Microbial Cell Factories, Vol 6, Iss 1, p 21 (2007)
Universitat Autònoma de Barcelona
Microbial Cell Factories
Microbial Cell Factories, Vol 6, Iss 1, p 21 (2007)
Background The analysis of transcriptional levels of the genes involved in protein synthesis and secretion is a key factor to understand the host organism's responses to recombinant protein production, as well as their interaction with the cultivatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee7cb116068a575b35e231845d71c33
https://ddd.uab.cat/record/112894
https://ddd.uab.cat/record/112894
