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pro vyhledávání: '"David Raymond Stover"'
Autor:
Kenneth A. Walsh, David Raymond Stover
Publikováno v:
Molecular and Cellular Biology. 14:5523-5532
We describe a potential regulatory mechanism for the transmembrane protein-tyrosine phosphatase CD45. Phosphorylation on both tyrosine and serine residues in vitro results in an activation of CD45 specifically toward one artificial substrate but not
Autor:
Feng Cong, Ingo Klagge, Rita Schmitz, Peter Finan, Seth Ettenberg, Renee Walsh, Michael P. Daley, Stephen E. Fawell, Holger Heine, Darrin Stuart, Jing Yuan, Beatriz Ospina, Rebecca A. Mosher, David Raymond Stover, Alwin Schuller, Yung-mae Yao, Karen Vincent, Sharon Li, Lance Ostrom, William R. Sellers, Jeffery A. Porter, Qunyan Yu, J. E. F. Green, Zhenping Zhu, K. Felix Hartlepp, Olga Charlat, Shanming Liu, Sanela Bilic
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(35)
Disregulated Wnt/β-catenin signaling has been linked to various human diseases, including cancers. Inhibitors of oncogenic Wnt signaling are likely to have a therapeutic effect in cancers. LRP5 and LRP6 are closely related membrane coreceptors for W
Publikováno v:
The Journal of biological chemistry. 268(10)
It has been reported that alteration of deletion of critical residues within one of the two homologous protein tyrosine phosphatase (PTPase)-like domains of CD45 completely abolishes all activity, suggesting that only the more N-terminal domain is ca
Autor:
David Raymond Stover, Kenneth Walsh
Publisher Summary This chapter discusses the identification of phosphorylation sites using a thiophosphorylated peptide and ESI-MS. Many sites of phosphorylation can be predicted by consensus motifs or homology to other phosphorylated proteins. By th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468251da0b5f3bd4c4c9c4a0f251078f
https://doi.org/10.1016/b978-0-12-058757-5.50027-5
https://doi.org/10.1016/b978-0-12-058757-5.50027-5
The leukocyte common antigen (CD45) is an abundant lymphocyte surface antigen that has been reported to be involved in signaling through the T-cell antigen receptor. CD45 is a transmembrane protein-tyrosine-phosphatase. An internal segment comprises
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2134904914ca9d72dc71f927f0b79a
https://europepmc.org/articles/PMC52370/
https://europepmc.org/articles/PMC52370/