Zobrazeno 1 - 10
of 78
pro vyhledávání: '"David Rabuka"'
Autor:
Maxine Bauzon, Penelope M. Drake, Robyn M. Barfield, Brandon M. Cornali, Igor Rupniewski, David Rabuka
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Oncology treatment has been revolutionized by the introduction of immune checkpoint inhibitor drugs, which enable 20–40% of patients to generate anti-tumor immune responses. Combination treatment approaches with chemotherapeutic drugs may enable re
Externí odkaz:
https://doaj.org/article/485d4ac33e984703b5b4c626ef35afe2
Autor:
Efrat T. Harel, Penelope M. Drake, Robyn M. Barfield, Irene Lui, Shauna Farr-Jones, Laura Van’t Veer, Zev J. Gartner, Evan M. Green, André Luiz Lourenço, Yifan Cheng, Byron C. Hann, David Rabuka, Charles S. Craik
Publikováno v:
Antibodies, Vol 8, Iss 4, p 54 (2019)
A promising molecular target for aggressive cancers is the urokinase receptor (uPAR). A fully human, recombinant antibody that binds uPAR to form a stable complex that blocks uPA-uPAR interactions (2G10) and is internalized primarily through endocyto
Externí odkaz:
https://doaj.org/article/7ba679cb5b3b4d9787ad97d8bf10cae8
Autor:
Thomas Linz, Dominick Yeo, Qiuting Hong, Wesley Zmolek, Jesse McFarland, Robyn M. Barfield, William E. Haskins, David Rabuka
Publikováno v:
Antibodies, Vol 7, Iss 4, p 40 (2018)
We hypothesized that systematic liquid chromatography-tandem mass spectrometry investigations of an antibody⁻drug conjugate (ADC), its small and large molecular components, and surrogate small-molecule conjugates might comprise a simple and efficie
Externí odkaz:
https://doaj.org/article/63ada5e5c2664dcd99410c2445575d63
Autor:
David Rabuka, Romas Kudirka, Betty C.B. Huang, Yun Cheol Kim, Wesley Zmolek, Robyn M. Barfield, Stefanie Bañas, Jesse M. McFarland, Adam Carlson, Penelope M. Drake
Fig S1. ELISA formats for detection of various analytes. Fig S2. Biophysical characterization of CAT-02-106. Fig S3. Competitive ELISA data showing CAT-02-106 binding to CD22. Fig S4. CAT-02-106 internalization on Ramos, Granta-519, and WSU-DLCL2 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b061d63aeb488ff9f9eb2b96c07bb83f
https://doi.org/10.1158/1535-7163.22504890.v1
https://doi.org/10.1158/1535-7163.22504890.v1
Autor:
David Rabuka, Romas Kudirka, Betty C.B. Huang, Yun Cheol Kim, Wesley Zmolek, Robyn M. Barfield, Stefanie Bañas, Jesse M. McFarland, Adam Carlson, Penelope M. Drake
Hematologically derived tumors make up ∼10% of all newly diagnosed cancer cases in the United States. Of these, the non-Hodgkin lymphoma (NHL) designation describes a diverse group of cancers that collectively rank among the top 10 most commonly di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::326daf17020ed6594142dfbb4a67ee7c
https://doi.org/10.1158/1535-7163.c.6537888.v1
https://doi.org/10.1158/1535-7163.c.6537888.v1
Autor:
Penelope M. Drake, David Rabuka, Mark D. Pegram, Colin Hickle, Dominick Yeo, Ayodele O. Ogunkoya, Maxine Bauzon, Fangjiu Zhang, Stepan Chuprakov, Yun Cheol Kim, Robyn M. Barfield
Contains 3 tables and 8 figures with legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b90b891f0338273763849f4ed50af1
https://doi.org/10.1158/1535-7163.22521129
https://doi.org/10.1158/1535-7163.22521129
Autor:
David Rabuka, Romas Kudirka, Betty C.B. Huang, Yun Cheol Kim, Wesley Zmolek, Robyn M. Barfield, Stefanie Bañas, Jesse M. McFarland, Adam Carlson, Penelope M. Drake
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8db831336faa6249c027cf39258c18
https://doi.org/10.1158/1535-7163.22504887
https://doi.org/10.1158/1535-7163.22504887
Autor:
David Rabuka, Romas Kudirka, Betty C.B. Huang, Yun Cheol Kim, Wesley Zmolek, Robyn M. Barfield, Stefanie Bañas, Jesse M. McFarland, Adam Carlson, Penelope M. Drake
Supplementary Methods and Synthesis of RED-106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32eed6e714d3af2e167d8c09ec4304ee
https://doi.org/10.1158/1535-7163.22504884
https://doi.org/10.1158/1535-7163.22504884
Bacteriophages encode anti-CRISPR (Acr) proteins that inactivate CRISPR-Cas bacterial immune systems, allowing successful invasion, replication, and prophage integration. Acr proteins inhibit CRISPR-Cas systems using a wide variety of mechanisms. Acr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea42b55936e8a240eb9c6e438d77a0d
https://doi.org/10.1101/2023.03.29.534776
https://doi.org/10.1101/2023.03.29.534776
Autor:
Allison Sharrar, Luisa Arake de Tacca, Trevor Collingwood, Zuriah Meacham, David Rabuka, Johanna Staples-Ager, Michael Schelle
Small CRISPR-Cas effectors are key to developing gene editing therapies due to the packaging constraints in viral vectors. While Cas9 and Cas12a CRISPR-Cas effectors have advanced into select clinical applications, their size is prohibitive for effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a682059c2bcff4e97a3d735bcb844cd5
https://doi.org/10.1101/2023.02.03.527072
https://doi.org/10.1101/2023.02.03.527072