Zobrazeno 1 - 10
of 30
pro vyhledávání: '"David R. Whikehart"'
Common cryopreservation media deplete corneal endothelial cell plasma membrane Na+,K+ATPase activity
Publikováno v:
Current Eye Research. 15:263-271
This study describes the effects of three cryopreservation media on the specific activity of corneal endothelial plasma membrane Na+,K+ ATPase activity, a transporter required for the fluid pump in the cornea. Bovine corneal endothelial cell cultures
Publikováno v:
Cornea. 14:295-299
Mannitol was introduced into the media of bovine corneal endothelial cells grown in culture. This was accomplished in order to compare its influence on Na,K-ATPase activity with that of high levels of glucose that inhibit the enzyme. The study was co
Publikováno v:
Ophthalmic Research. 26:17-22
Eight putative, low-molecular-weight peptides have been found in the media of bovine corneal tissue cocultures and in bovine aqueous fluid. By investigating amine fluid extracts from these sources by HPLC, possible amino acids, vitamins and urea were
Autor:
David R. Whikehart, Neng-Hua Guo, Vivian S. Zabrenetzky, David D. Roberts, Tikva Vogel, Diane A. Blake
Publikováno v:
Journal of Cellular Physiology. 157:359-366
Bovine corneal endothelial cells showed a strong migratory response to specific simple sugars (D-glucose and sucrose, but not L-glucose, sorbitol, lactose, or D-galactose) at concentrations above 10 mM. Checkerboard analysis of the migratory response
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 8:107-114
Bovine, non-pigmented, ciliary body epithelial cells were isolated and grown in culture to determine whether timolol maleate might affect the activity of their plasma membrane ATPases. The possible effects were tested in drug concentrations in a rang
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 7:195-200
An effort was made to determine whether the beta-blocking agents: timolol maleate and betaxolol hydrochloride could affect the activity of the plasma membrane, transport ATPases of corneal endothelial and epithelial cells grown in culture. It was fou
Publikováno v:
Cornea. 10:54-58
There are no quantitative studies on the uptake of alkali into corneal tissues. To study this phenomenon, both type I collagen and bovine corneas were incubated in sodium hydroxide (NaOH) under varying conditions for periods up to 27.5 h. The sorptio
Publikováno v:
Molecular vision. 13
The corneal endothelium is a monolayer of cells in the posterior cornea that is responsible for maintaining a clear cornea. Corneal endothelial cells may be induced to divide, but it has been held that they do not divide in the normal cornea of an ad
Publikováno v:
Molecular vision. 11
The well-known reluctance of human corneal endothelial cells (HCECs) to divide has continually intrigued investigators. Related to this, the discovery of an increased endothelial cell population in the periphery of the human cornea has prompted an in
Autor:
Amanda C, Paull, David R, Whikehart
Publikováno v:
Molecular vision. 11
To determine the protein and mRNA expression of p53, p63, and p73 in central and peripheral human corneal endothelial cells. Since these proteins are known to be involved in the regulation of cell division, this study seeks information about their in