Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David R. Weyna"'
Autor:
Gautam R. Desiraju, Srinivasulu Aitipamula, Miranda L. Cheney, Changquan Calvin Sun, Preetam P. Ghogale, Soumyajit Ghosh, T. Rajamannar, David R. Weyna, Venu R. Vangala, Rahul Banerjee, Gargi Mukherjee, Palash Sanphui, T. N. Guru Row, Arvind K. Bansal, Ram Thaimattam, Robin D. Rogers, Arunachalam Ramanan, Jennifer A. Swift, Piotr H. Karpinski, Kumar Biradha, Naír Rodríguez-Hornedo, Amol G. Dikundwar, C. Malla Reddy, Allan S. Myerson, Angshuman Roy Choudhury, Ning Shan, Brian Moulton, Rajesh Kumar Thaper, Sajesh P. Thomas, Naga Kiran Duggirala, Srinu Tothadi, Ritesh Dubey, Ram K. R. Jetti, Pramod Kumar Goswami, Narayan Variankaval, Ganesh Shete, Dinesh Kumar, Michael J. Zaworotko, Tejender S. Thakur, Arijit Mukherjee, Peddy Vishweshwar, Poonam Kaushik, N. Rajesh Goud, Vibha Puri, Vineet Kumar, Amit Singh
Publikováno v:
Crystal Growth & Design. 12:2147-2152
The December 2011 release of a draft United States Food and Drug Administration (FDA) guidance concerning regulatory classification of pharmaceutical cocrystals of active pharmaceutical ingredients (APIs) addressed two matters of topical interest to
Autor:
Mazen Hanna, Michael J. Zaworotko, Łukasz Wojtas, David R. Weyna, Ning Shan, Miranda L. Cheney
Publikováno v:
CrystEngComm. 14:2377-2380
Pharmaceutical cocrystals of tadalafil with methylparaben, propylparaben and hydrocinnamic acid have been prepared and characterized. The crystal packing observed in the three resulting cocrystals reveals that tadalafil molecules form persistent hydr
Autor:
Ning Shan, Miranda L. Cheney, Lukasz Wojtas, David R. Weyna, Michael J. Zaworotko, Mazen Hanna
Publikováno v:
Journal of Pharmaceutical Sciences. 100:2172-2181
Meloxicam is a nonsteroidal anti-inflammatory drug with low aqueous solubility and high permeability. Because of its low solubility under acidic conditions (e.g., pH 1-5), it can take more than 2 h for meloxicam to reach its therapeutic concentration
Autor:
Mazen Hanna, Michael J. Zaworotko, Miranda L. Cheney, David R. Weyna, Lukasz Wojtas, Ning Shan
Publikováno v:
Crystal Growth & Design. 10:4401-4413
Meloxicam is a nonsteroidal anti-inflammatory drug with low aqueous solubility and high permeability prescribed for indications of arthritis, primary dysmenorrhea, fever, and pain. In this contribution, we apply crystal engineering and the supramolec
Publikováno v:
Crystal Growth & Design. 9:1106-1123
The reliability of solvent drop grinding (SDG), also referred to as liquid assisted grinding, wet cogrinding, or mechanochemistry, to facilitate cocrystal formation is addressed with a series of model cocrystals and pharmaceutical cocrystals. The syn
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 182:563-567
Benzyl 5-(diisopropoxyphosphoryl)pentanoate (benzyl diisopropyl 5-phosphonopentanoate) was synthesized from 5-bromopentanoic acid in three steps. The first step esterified 5-bromopentanoic acid with benzyl alcohol, the second step was a Finkelstein h
Publikováno v:
ChemInform. 46
Introduction: Pharmaceutical cocrystallization has emerged in the past decade as a new strategy to enhance the clinical performance of orally administered drugs. A pharmaceutical cocrystal is a multi-component crystalline material in which the active
Publikováno v:
Expert opinion on drug metabolismtoxicology. 10(9)
Pharmaceutical cocrystallization has emerged in the past decade as a new strategy to enhance the clinical performance of orally administered drugs. A pharmaceutical cocrystal is a multi-component crystalline material in which the active pharmaceutica
Autor:
Mazen Hanna, Vasyl Sava, Miranda L. Cheney, Michael J. Zaworotko, David R. Weyna, Juan Sanchez-Ramos, Shijie Song, Ning Shan
Publikováno v:
Molecular pharmaceutics. 9(7)
Meloxicam is a nonsteroidal anti-inflammatory drug prescribed for rheumatoid arthritis, osteoarthritis, postoperative pain and fever. Meloxicam exhibits low solubility in acidic aqueous media and a slow onset of action in biological subjects. An oral
Publikováno v:
Molecular pharmaceutics. 4(3)
An analysis of the Cambridge Structural Database reveals99% occurrence of the hydroxyl...pyridine supramolecular heterosynthon in crystal structures that contain hydroxyl and pyridine moieties in the absence of other hydrogen-bonding moieties. The oc