Zobrazeno 1 - 10 of 37 pro vyhledávání: '"David R. Uncles"'
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LIPAEMIC Report: Results of Clinical Use of Intravenous Lipid Emulsion in Drug Toxicity Reported to an Online Lipid Registry
Autor: David R. Uncles, Johann Willers, Martyn Harvey, T. Meek, Grant Cave, John Picard, Guy L. Weinberg
Publikováno v: Journal of Medical Toxicology. 10:133-142
The use of intravenous lipid emulsion (ILE) as an antidote has prompted significant academic and clinical interest. Between August 2009 and August 2012, data from cases of ILE use in intoxicated patients in different hospitals on different continents
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e865c5efdabc8b78f35e99c70b3fb316
https://doi.org/10.1007/s13181-013-0375-y
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3
Co-induction of anaesthesia with 0.75 mg kg−1 propofol followed by sevoflurane
Autor: R. Venn, J. O’Dwyer, C. Jenkins, K. Stock, S. Panayiotou, David R. Uncles, K. Kelley, A. P. Moran, C. Spring
Publikováno v: European Journal of Anaesthesiology. 25:183-187
BACKGROUND The induction of general anaesthesia is associated with the greatest cardiovascular changes in elderly patients. Induction can be performed either intravenously or with gaseous induction. Sevoflurane has advantages over propofol for induct
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e45500f2448d0955a16adde437caf303
https://doi.org/10.1017/s026502150700138x
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4
0044 Ultrasound assisted extreme surgical airway simulation
Autor: Neal Reynolds, Wendy Collyer, Anna Roberts, Matthew Staniforth, Johann Willers, David R. Uncles
Publikováno v: Prize poster presentations.
Background Performing emergency cricothyriodotomy is an integral part of difficult airway management, and this technique is widely taught via simulation using animal, homemade surgical and commercial models. Landmarks for these procedures are usually
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::715da48901faac338fcbc7abf0b7395a
https://doi.org/10.1136/bmjstel-2015-000075.68
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5
Nitric Oxide Modulation of Pulmonary Vascular Resistance Is Red Blood Cell Dependent in Isolated Rat Lungs
Autor: C. M. Roos, Mark O. Daugherty, George F. Rich, David R. Uncles, Deborah U. Frank
Publikováno v: Anesthesia & Analgesia. 83:1212-1217
Nitric oxide (NO) or endothelium-derived relaxing factor may play an important role in modulating pulmonary vascular resistance (PVR), although previous studies have produced conflicting results. Endogenous NO inhibition causes an increase in PVR in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142c43516c7dcc30fe982a3c6064bd40
https://doi.org/10.1097/00000539-199612000-00014
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6
The use of dye surrogates to illustrate local anesthetic drug sequestration by lipid emulsion: a visual demonstration of the lipid sink effect
Autor: T. L. Samuels, David R. Uncles, A. Papadopoulou, Johann Willers
Publikováno v: Regional anesthesia and pain medicine. 37(2)
Background and Objectives We hypothesized that by substituting a dye surrogate in place of local anesthetic, we could visually demonstrate dye sequestration by lipid emulsion that would be dependent on both dye lipophilicity and the amount of lipid e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372e5be021de542499816ea896d0c6f0
https://pubmed.ncbi.nlm.nih.gov/22354065
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In vitro suppression of drug-induced methaemoglobin formation by Intralipid(®) in whole human blood: observations relevant to the 'lipid sink theory'
Autor: R. Monteiro, C. Halloran, Johann Willers, Hongsheng Dai, T. L. Samuels, David R. Uncles
Publikováno v: AnaesthesiaReferences. 67(1)
To provide further evidence for the lipid sink theory, we have developed an in vitro model to assess the effect of Intralipid® 20% on methaemoglobin formation by drugs of varying lipid solubility. Progressively increasing Intralipid concentrations f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13b50ba7dc3927a121c30b28c0ba076
https://pubmed.ncbi.nlm.nih.gov/21999405
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8
Progressive Encephalomyelitis with Rigidity and Myoclonus
Autor: A. Papadopoulou, T. L. Samuels, Asitha Dassanayake, Colin Spring, Johann Willers, David R. Uncles
Publikováno v: A & A Case Reports. 2:81-82
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare autoimmune neurological condition. Antibodies targeting glycine receptors (GlyR) have been implicated in PERM. Because GlyR activity is enhanced by inhaled anesthetic drugs at
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47822325d5baa8803534ed87e29d52ab
https://doi.org/10.1097/acc.0b013e3182a6d853
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A meta-analysis on the clinical effectiveness of transversus abdominis plane block
Autor: Muhammed Rafay Sameem Siddiqui, Mirza K. Baig, Liz Cheek, M. S. Sajid, David R. Uncles
Publikováno v: Journal of clinical anesthesia. 23(1)
To study the efficacy of the transversus abdominal plane (TAP) block.Meta-analysis.District general hospital.86 patients in the TAP block group and 88 in the non-TAP block group.Statistical analyses were performed using Microsoft Excel 2007 for Windo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011d3ec2e6cb3c9773d9c9a05a4c3be3
https://pubmed.ncbi.nlm.nih.gov/21296242
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