Zobrazeno 1 - 9
of 9
pro vyhledávání: '"David R. Sage"'
Autor:
Jian Ding, Guo Li, Hejun Liu, Lulu Liu, Ying Lin, Jingyan Gao, Guoqiang Zhou, Lingling Shen, Mengxi Zhao, Yanyan Yu, Weihui Guo, Ulrich Hommel, Johannes Ottl, Jutta Blank, Nicola Aubin, Yi Wei, Hu He, David R. Sage, Peter W. Atadja, En Li, Rishi K. Jain, John A. Tallarico, Stephen M. Canham, Ying-Ling Chiang, He Wang
Publikováno v:
ACS Chemical Biology. 18:34-40
WD repeat domain 5 (WDR5) is a member of the WD40-repeat protein family that plays a critical role in multiple processes. It is also a prominent target for pharmacological inhibition in diseases such as cancer, aging, and neurodegenerative disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be8f58a3f8f57cbd62279d195187665
https://doi.org/10.1021/acschembio.2c00843
https://doi.org/10.1021/acschembio.2c00843
Autor:
David R. Sage, Joyce D. Fingeroth, Maria Zambela-Soediono, Jennifer Roecklein-Canfield, Michael Gill, Marc E. Uknis, Nina Longtine
Publikováno v:
Journal of Cell Science. 117:2709-2720
CD21 is a multifunctional receptor for Epstein-Barr virus (EBV), for C3dg and for CD23. Upon engagement of immune complexes CD21 modulates immunoreceptor signaling, linking innate and adaptive immune responses. The mechanisms enabling CD21 to indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d40b0d7799b9608c8e028287bc40b0
https://doi.org/10.1242/jcs.01113
https://doi.org/10.1242/jcs.01113
Autor:
Joyce D. Fingeroth, Deep Agnani, Mohamed S. Arredouani, Laura Dunn, Manoj Bhasin, Towia A. Libermann, David R. Sage, Michael Gill
Publikováno v:
Journal of virology. 88(10)
Epstein-Barr virus (EBV) attachment to human CD21 on the B-cell surface initiates infection. Whether CD21 is a simple tether or conveys vital information to the cell interior for production of host factors that promote infection of primary B cells is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e7acce3920975d2800f42e35ddde8f
https://pubmed.ncbi.nlm.nih.gov/24600013
https://pubmed.ncbi.nlm.nih.gov/24600013
Autor:
Ching Yim, Joyce D. Fingeroth, David R. Sage, Robert W. Finberg, William L. Marshall, Erik Gustafson, Louisa Williams, Thomas Graf, Katherine Hanify
Publikováno v:
Journal of Virology. 73:5181-5185
The sequenced gammaherpesviruses each contain a single viral bcl-2 homolog (v- bcl-2 ) which may encode a protein that functions in preventing the apoptotic death of virus-infected cells. Epstein-Barr virus (EBV), a gammaherpesvirus associated with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05dd72e764ed7ed2cb67eb8de43a48ca
https://doi.org/10.1128/jvi.73.6.5181-5185.1999
https://doi.org/10.1128/jvi.73.6.5181-5185.1999
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:2923-2931
The Epstein-Barr virus (EBV) thymidine kinase (TK) was expressed in mammalian 143B TK − cells to investigate its substrate specificity. The herpes simplex virus type 1 (HSV-1) TK was similarly expressed for comparison. Both viral TKs conferred a TK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667f54aa22c00403380a13fc53e486c1
https://doi.org/10.1128/aac.42.11.2923
https://doi.org/10.1128/aac.42.11.2923
Publikováno v:
Blood. 85:1289-1299
Recombination activating genes 1 and 2 (RAG-1 and RAG-2), are the only lymphoid-specific genes required for the site-directed recombination reaction leading to generation of B-cell receptors and T-cell receptors (TCRs). RAGs are normally expressed du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d931e493da0572966a36348a1679a891
https://doi.org/10.1182/blood.v85.5.1289.bloodjournal8551289
https://doi.org/10.1182/blood.v85.5.1289.bloodjournal8551289
Autor:
Michael Detmar, Towia A. Libermann, Jay W. Shin, David R. Sage, Kimberly E. Foreman, Joyce D. Fingeroth, Young-Kwon Hong, Christine L. Curry, Satoshi Hirakawa, Bruce J. Dezube
Publikováno v:
Nature genetics. 36(7)
Kaposi sarcoma is considered a neoplasm of lymphatic endothelium infected with Kaposi sarcoma-associated herpesvirus. It is characterized by the expression of lymphatic lineage-specific genes by Kaposi sarcoma tumor cells. Here we show that infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a689705084dda758d9eac6ff6a5f2706
https://pubmed.ncbi.nlm.nih.gov/15220917
https://pubmed.ncbi.nlm.nih.gov/15220917
Publikováno v:
Blood. 100(3)
Kaposi sarcoma–associated herpesvirus (KSHV)/human herpesvirus-8 (HHV-8) is causally associated with Kaposi sarcoma (KS). The absence of a cell culture system that effectively reproduces the composite mechanisms governing initiation and maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efc296b52ed49002599616c9508eb35
https://pubmed.ncbi.nlm.nih.gov/12130499
https://pubmed.ncbi.nlm.nih.gov/12130499
Publikováno v:
Journal of virology. 73(3)
Epstein-Barr virus (EBV) is invariably present in undifferentiated nasopharyngeal carcinomas, is found sporadically in other carcinomas, and replicates in the differentiated layer of the tongue epithelium in lesions of oral hairy leukoplakia. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb01cd10dbba67f420fa56a2f26a2c7
https://pubmed.ncbi.nlm.nih.gov/9971794
https://pubmed.ncbi.nlm.nih.gov/9971794