Zobrazeno 1 - 10
of 20
pro vyhledávání: '"David R. Penas"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 7, p e1011642 (2024)
The Virtual Epileptic Patient (VEP) refers to a computer-based representation of a patient with epilepsy that combines personalized anatomical data with dynamical models of abnormal brain activities. It is capable of generating spatio-temporal seizur
Externí odkaz:
https://doaj.org/article/af1e1b5ca08e4992b0f50864278501c3
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011151 (2024)
The mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Computational models provide a particularly systematic and systemic description of the mechanisms governing mammalian cell cycle control. By combining bo
Externí odkaz:
https://doaj.org/article/81586cd017274a318d31d29f6269b022
The mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Computational models provide a particularly systematic and systemic description of the mechanisms governing mammalian cell cycle control. By combining bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b5298db5c8f0743409412f51928ce3b
https://doi.org/10.1101/2023.05.04.539349
https://doi.org/10.1101/2023.05.04.539349
This work presents a methodology to evaluate the bioenergetic feasibility of alternative metabolic pathways for a given microbial conversion, optimising their energy yield and driving forces as a function of the concentration of metabolic intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919584b55f808209c6cfd1eeecc5008e
https://doi.org/10.1101/2023.02.13.528271
https://doi.org/10.1101/2023.02.13.528271
Resource assignment and scheduling models provides an automatic and fast decision support system for wildfire suppression logistics. However, this process generates challenging optimization problems in many real-world cases, and the computational tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b080e1b31f64e233c6c3562c253fbefb
https://hdl.handle.net/10347/30369
https://hdl.handle.net/10347/30369
Publikováno v:
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
instname
This paper presents a new formulation for the routing problem in which the available fleet consists of trucks and trailers divided into compartments. Solving the model for large instances is computationally expensive. Therefore, we introduce and impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fa60af26496e240af49016c54e1cd2
https://doi.org/10.1111/itor.13071
https://doi.org/10.1111/itor.13071
Autor:
David R Penas, David Henriques, Patricia González, Ramón Doallo, Julio Saez-Rodriguez, Julio R Banga
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182186 (2017)
We consider a general class of global optimization problems dealing with nonlinear dynamic models. Although this class is relevant to many areas of science and engineering, here we are interested in applying this framework to the reverse engineering
Externí odkaz:
https://doaj.org/article/bebe59a128fe4251b2a2436fea9c06a1
Autor:
Brais González-Rodríguez, Joaquín Ossorio-Castillo, Julio González-Díaz, Ángel M. González-Rueda, David R. Penas, Diego Rodríguez-Martínez
In this paper we introduce RAPOSa, a global optimization solver specifically designed for (continuous) polynomial programming problems with box-constrained variables. Written entirely in C++, RAPOSa is based on the Reformulation-Linearization (Sheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8eda14321643dae0953eae7bb210ccc
https://hdl.handle.net/10347/29971
https://hdl.handle.net/10347/29971
Autor:
Marcos Raydan, David R. Penas
Solving nonlinear programming problems usually involve difficulties to obtain a starting point that produces convergence to a local feasible solution, for which the objective function value is sufficiently good. A novel approach is proposed, combinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d58555dcf7a9305f1f2ac8890614f59
https://hdl.handle.net/10362/121434
https://hdl.handle.net/10362/121434
Publikováno v:
RUC. Repositorio da Universidade da Coruña
instname
e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
instname
e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
Statistical fisheries models are frequently used by researchers and agencies to understand the behavior of marine ecosystems or to estimate the maximum acceptable catch of different species of commercial interest. The parameters of these models are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e99d551e05107c42de1c5b1f48c314a
https://hdl.handle.net/2183/27611
https://hdl.handle.net/2183/27611