Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David R. Morcock"'
Autor:
Leslie Renee Cockerham, Steven A. Yukl, Kara Harvill, Ma Somsouk, Sunil K. Joshi, Elizabeth Sinclair, Teri Liegler, Rebecca Hoh, Sophie Lyons, Peter W. Hunt, Adam Rupert, Irini Sereti, David R. Morcock, Ajantha Rhodes, Claire Emson, Marc K. Hellerstein, Jacob D. Estes, Sharon Lewin, Steven G. Deeks, Hiroyu Hatano
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 3, Pp 310-334 (2017)
Background: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) re
Externí odkaz:
https://doaj.org/article/33ba8fcfdd47470c8750883f7586966d
Autor:
Claire Deleage, Stephen W. Wietgrefe, Gregory Del Prete, David R. Morcock, Xing-Pei Hao, Michael Piatak, Jr., Julian Bess, Jodi L. Anderson, Katherine Perkey, Cavan Reilly, Joseph M. McCune, Ashley T. Haase, Jeffrey D. Lifson, Timothy W. Schacker, Jacob D. Estes
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 1, Pp 68-106 (2016)
A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymphoid tissue
Externí odkaz:
https://doaj.org/article/f51bb6a8e6df4f68b7e5810c43614a4c
Autor:
Netanya S Utay, Annelys Roque, J Katherina Timmer, David R Morcock, Claire DeLeage, Anoma Somasunderam, Amy C Weintrob, Brian K Agan, Jacob D Estes, Nancy F Crum-Cianflone, Daniel C Douek
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005580 (2016)
People with HIV infection are at increased risk for community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs). Lower CD4 T-cell counts, higher peak HIV RNA levels and epidemiological factors may
Externí odkaz:
https://doaj.org/article/47e17dc096244c13bd0df032bfe2a629
Autor:
Michael Hull, Jacob D. Estes, Randy Fast, Joshua A. Kramer, Laura Newman, Rodney Wiles, Rebecca Shoemaker, William J. Bosche, Claire Deleage, Christine M. Fennessey, Tyler Malys, James A. Thomas, Charles M. Trubey, Lorna Silipino, Vicky Coalter, Gregory Q. Del Prete, Jeffrey D. Lifson, Cathi Pyle, Duncan Donohue, Adam Wiles, Jacob Kiser, Brandon F. Keele, David R. Morcock, Adrienne E. Swanstrom, Taina T. Immonen, Kelli Oswald, Matthew W. Breed
Publikováno v:
J Clin Invest
The effectiveness of virus-specific strategies, including administered HIV-specific mAbs, to target cells that persistently harbor latent, rebound-competent HIV genomes during combination antiretroviral therapy (cART) has been limited by inefficient
Publikováno v:
J Vis Exp
In situ hybridization is a powerful technique to identify specific RNA or DNA sequences within individual cells in tissue sections, providing important insights into physiological processes and disease pathogenesis. In situ hybridization (ISH) has be
Autor:
Sophie Lyons, Marc K. Hellerstein, David R. Morcock, Kara Harvill, Teri Liegler, Sunil K. Joshi, Steven G. Deeks, Ma Somsouk, Hiroyu Hatano, Elizabeth Sinclair, Claire Emson, Peter W. Hunt, Rebecca Hoh, Sharon R Lewin, Steven A. Yukl, Irini Sereti, Ajantha Rhodes, Adam Rupert, Leslie R. Cockerham, Jacob D. Estes
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 3, Pp 310-334 (2017)
Pathogens & immunity, vol 2, iss 3
Pathogens & immunity, vol 2, iss 3
Background: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) re
Autor:
Jodi Anderson, Ashley T. Haase, Cavan S. Reilly, Jacob D. Estes, Michael Piatak, Stephen W. Wietgrefe, David R. Morcock, Gregory Q. Del Prete, Katherine Perkey, Timothy W. Schacker, Joseph M. McCune, Xing Pei Hao, Claire Deleage, Jeffrey D. Lifson, Julian W. Bess
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 1, Pp 68-106 (2016)
A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymphoid tissue
Autor:
Peter D. Burbelo, David R. Morcock, Stig M. R. Jensen, Jacob D. Estes, Virginia Sheikh, Leah Osnos, Ven Natarajan, Stephen B. Kovacs, Joseph W. Adelsberger, Thérèse Croughs, William L. Thompson, Jeffrey S. Bourgeois, Ainhoa Perez-Diez, Jeanette Higgins, Adam Rupert, Irina Maric, JoAnn M. Mican, Alexandra F. Freeman, Irini Sereti, Michael D. Yao, Alice Pau, Gregg Roby, Brian O. Porter, Rebecca DerSimonian
Publikováno v:
Blood. 127:977-988
Idiopathic CD4 lymphopenia (ICL) is a rare syndrome defined by low CD4 T-cell counts (
Autor:
Christian Suloway, David R. Morcock, Hyun Jung, Yanling Liu, Jack R. Collins, Curtis Lisle, Elijah F. Edmondson, Claire Deleage, Tianyi Miao
Publikováno v:
AIPR
Characterization of collagen deposition in immunostained images is relevant to various pathological conditions, particularly in human immunodeficiency virus (HIV) infection. Accurate segmentation of these collagens and extracting representative featu
Autor:
Romas Geleziunas, Richard Lum, Haesun Park, Vanessa M. Hirsch, Jin Young Bae, Alfred W. Legasse, David R. Morcock, Claire Deleage, Afam A. Okoye, Tonya Swanson, Kenta Matsuda, Rebecca Shoemaker, Louis J. Picker, Michael K. Axthelm, Jeffrey D. Lifson, Carissa Lucero, Yoshinori Fukazawa, Jacob D. Estes, Joseph Hesselgesser, Paul T. Edlefsen, Michael Piatak, Shoko I. Hagen
Publikováno v:
Nature medicine
Chronic-phase HIV and simian immunodeficiency virus (SIV) replication is reduced by as much as 10,000-fold in elite controllers (ECs) compared with typical progressors (TPs), but sufficient viral replication persists in EC tissues to allow viral sequ