Zobrazeno 1 - 10
of 35
pro vyhledávání: '"David R. McMillen"'
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
We revisited the mathematical model of the chemostat and examined consequences of considerably decreasing the concentration of limiting nutrient in the inflow for the growth of both the planktonic and biofilm cells in the chemostat tank (fermenter).
Externí odkaz:
https://doaj.org/article/1b439261e90f445ca713336c550ae5d0
Autor:
Criselda Jean G. Cruz, Richard Kil, Stanley Wong, Louis C. Dacquay, Denise Mirano-Bascos, Pilarita T. Rivera, David R. McMillen
Publikováno v:
ACS Synthetic Biology. 11:2938-2946
Malaria, a disease caused by the
Autor:
David R. McMillen, Louis C Dacquay
Publikováno v:
FEMS Yeast Research
Transcription factor (TF)-based biosensors have proven useful for increasing biomanufacturing yields, large-scale functional screening, and in environmental monitoring. Most yeast TF-based biosensors are built from natural promoters, resulting in lar
Autor:
David R. McMillen, Brendan J. Hussey
Publikováno v:
Nucleic Acids Research
Despite recent progress on synthetic transcription factor generation in eukaryotes, there remains a need for high-activity bacterial versions of these systems. In synthetic biology applications, it is useful for transcription factors to have two key
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology
Frontiers in Microbiology
We revisited the mathematical model of the chemostat and examined consequences of considerably decreasing the concentration of limiting nutrient in the inflow for the growth of both the planktonic and biofilm cells in the chemostat tank (fermenter).
Autor:
Mostafizur Mazumder, David R. McMillen
Publikováno v:
Nucleic Acids Research
Modularity in controlling gene expression artificially is becoming an essential aspect of synthetic biology. Artificial transcriptional control of gene expression is one of the most well-developed methods for the design of novel synthetic regulatory
Publikováno v:
ACS synthetic biology. 6(4)
It is increasingly practical to co-opt many native cellular components into use as elements of synthetic biological systems. We present the design and experimental investigation of the first exogenous genetic construct to be successfully targeted by
Publikováno v:
ACS Synthetic Biology
Synthetic biology may be viewed as an effort to establish, formalize, and develop an engineering discipline in the context of biological systems. The ability to tune the properties of individual components is central to the process of system design i
Autor:
David R. McMillen, Jordan Ang
Publikováno v:
Biophysical Journal. 104(2):505-515
Synthetic biology includes an effort to use design-based approaches to create novel controllers, biological systems aimed at regulating the output of other biological processes. The design of such controllers can be guided by results from control the
Publikováno v:
Physical Review E. 93
The growth rate and carrying capacity of a cell population are key to the characterization of the population's viability and to the quantification of its responses to perturbations such as drug treatments. Accurate estimation of these parameters nece