Zobrazeno 1 - 10
of 87
pro vyhledávání: '"David R. Manning"'
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0203170 (2018)
Primary cilia are solitary organelles that emanate from the plasma membrane during growth arrest in almost all mammalian cells. The canonical Hedgehog (HH) pathway requires trafficking of the G protein-coupled receptor SMOOTHENED (SMO) and the GLI tr
Externí odkaz:
https://doaj.org/article/c3ae9abe675b47678d2c435456e5ad1a
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197442 (2018)
The Hedgehog family of morphogens has long been known to utilize, through the 7-transmembrane protein Smoothened (Smo), the heterotrimeric G protein Gi in both canonical and noncanonical forms of signaling. Other G proteins, while not specifically ut
Externí odkaz:
https://doaj.org/article/730c0004abc74ee9b17d67bcf4dd63ab
Autor:
David R. Manning
Preface Expression and Purification of G Protein a Subunits in E. scherichia coli - M. Linder Purification of Recombinant G Protein a and bg Subunits from Sf9 Cells-T. Kozasa Expression and Functional Analysis of G Protein a Subunits in Mammalian Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659ec08ba72dbd3017c82abe2a0ae538
https://doi.org/10.1201/9780429129360
https://doi.org/10.1201/9780429129360
Autor:
Walter J. Koch, David R. Manning, Manuel Covarrubias, Moza M. Al-Owais, Natalia A. Riobo-Del Galdo, Lan Cheng, Chris Peers
Publikováno v:
Journal of Biological Chemistry. 293:11022-11032
SMO (Smoothened), the central transducer of Hedgehog signaling, is coupled to heterotrimeric Gi proteins in many cell types, including cardiomyocytes. In this study, we report that activation of SMO with SHH (Sonic Hedgehog) or a small agonist, purmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3a24ce8d18e0fcd1e1f04d365213b3
https://doi.org/10.1074/jbc.ra118.001989
https://doi.org/10.1074/jbc.ra118.001989
Autor:
David R. Manning
Incorporating a bench-top format, G Proteins: Techniques of Analysis covers essential methods - with a commitment to those techniques of proven and current utility. It offers an in-depth description of protocols, together with theory and representati
Publikováno v:
Progress in Nonhistone Protein Research ISBN: 9781351076050
Progress in Nonhistone Protein Research
Progress in Nonhistone Protein Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fc5f0296608a22e73a1a56e2c19877
https://doi.org/10.1201/9781351076050-2
https://doi.org/10.1201/9781351076050-2
Autor:
Lan, Cheng, Moza, Al-Owais, Manuel L, Covarrubias, Walter J, Koch, David R, Manning, Chris, Peers, Natalia A, Riobo-Del Galdo
Publikováno v:
The Journal of biological chemistry. 293(28)
SMO (Smoothened), the central transducer of Hedgehog signaling, is coupled to heterotrimeric G(i) proteins in many cell types, including cardiomyocytes. In this study, we report that activation of SMO with SHH (Sonic Hedgehog) or a small agonist, pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7210aecfcfaa5a038f21681addea5a4f
https://pubmed.ncbi.nlm.nih.gov/29802197
https://pubmed.ncbi.nlm.nih.gov/29802197
Autor:
Natalia A. Riobo-Del Galdo, David R. Manning, Lan Ho Wei, Ioanna Ch. Georgiou, Mohammad Arastoo
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0203170 (2018)
Primary cilia are solitary organelles that emanate from the plasma membrane during growth arrest in almost all mammalian cells. The canonical Hedgehog (HH) pathway requires trafficking of the G protein-coupled receptor SMOOTHENED (SMO) and the GLI tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362e9a57195ff7489243d0408e6a7141
http://europepmc.org/articles/PMC6110505?pdf=render
http://europepmc.org/articles/PMC6110505?pdf=render