Zobrazeno 1 - 10
of 57
pro vyhledávání: '"David R. Maguire"'
Autor:
Lisa R. Gerak, David R. Maguire, Gerta Cami-Kobeci, Keith M. Olson, John R. Traynor, Stephen M. Husbands, Charles P. France, Lisette Acevedo, Barbara Belli, Peter Flynn
Publikováno v:
Behavioural pharmacology. 33(6)
Drugs targeting mu opioid receptors are the mainstay of clinical practice for treating moderate-to-severe pain. While they can offer excellent analgesia, their use can be limited by adverse effects, including constipation, respiratory depression, tol
Autor:
David R. Maguire, Charles P. France
Publikováno v:
Journal of the Experimental Analysis of Behavior. 119:392-406
Publikováno v:
Drug and Alcohol Dependence. 244:109787
Publikováno v:
The FASEB Journal. 36
Autor:
David R, Maguire, Vanessa, Minervini
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 93
Opioid abuse continues to be a significant public health challenge, with rates of opioid-related overdose deaths increasing continuously over the last two decades. There also has been a sharp increase in overdose deaths involving stimulant drugs, pri
Autor:
David R. Maguire, Charles P. France
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 382(2)
Methocinnamox (MCAM), a long-acting
Autor:
Megan S. Abbott, Robert W. Seaman, Michelle R. Doyle, David R. Maguire, Kenner C. Rice, Gregory T. Collins
Publikováno v:
Addict Biol
Synthetic cathinones, such as 3,4-methylenedioxypyrovalerone (MDPV), are recreational drugs of abuse often identified in 'bath salts' preparations. Humans report compulsive patterns of bath salts use, and previous work suggests that a subset of rats
Autor:
Sanjana Mada, Lisa R. Gerak, Amélie Soyer, David R. Maguire, Zehua Hu, Vanessa Minervini, Christopher W. Cunningham, Charles P. France
Publikováno v:
Psychopharmacology. 237:3591-3602
Opioids remain the drugs of choice for treating moderate to severe pain, although adverse effects often limit use. Drugs acting concomitantly as agonists at μ opioid receptors and antagonists at δ opioid receptors produce antinociceptive effects wi
Publikováno v:
Behavioural Pharmacology. 31:216-220
The behavioral economics framework has been used extensively to study factors that control operant behavior, including quantification of reinforcing effectiveness of drugs of abuse. Generally, consumption of a commodity decreases with increasing pric
Publikováno v:
Perspect Behav Sci
The effective management of pain is a longstanding public health concern. Although opioids have been frontline analgesics for decades, they also have well-known undesirable effects that limit their clinical utility, such as abuse liability and respir