Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David R. Maass"'
Autor:
Paul H. Teesdale-Spittle, Veronica Venturi, David R. Maass, Paul H. Atkinson, Richard Little, Peter W. Bircham, Juliana Rodigheri Brito
Publikováno v:
Biochemical and Biophysical Research Communications. 496:1082-1087
The translation initiation machinery is emerging as an important target for therapeutic intervention, with potential in the treatment of cancer, viral infections, and muscle wasting. Amongst the targets for pharmacological control of translation init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dbaf7458ae1c2a29ea1d899c4ffe8e
https://doi.org/10.1016/j.bbrc.2018.01.137
https://doi.org/10.1016/j.bbrc.2018.01.137
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000597 (2009)
The carbohydrate larval antigen, CarLA, is present on the exposed surface of all strongylid nematode infective L3 larvae tested, and antibodies against CarLA can promote rapid immune rejection of incoming Trichostrongylus colubriformis larvae in shee
Externí odkaz:
https://doaj.org/article/59c716b60e3648c1bc3c1e48ced9787c
Autor:
David R. Maass, Charles B. Shoemaker, Jennifer Pfeil, Alf Hamann, Wayne R. Hein, Rudolf Volkmer, Ute Hoffmann, L G Moore, A. Pernthaner, Sally Cole, Sarah M. Rosanowski, Uta Lauer, Saleh Umair, Elisabeth E. Kenngott
Publikováno v:
Molecular Pharmaceutics. 13:202-210
In this study we identified and characterized a novel cyclic peptide that facilitates the rapid transportation of conjugated molecules across the epithelial layer of the small intestine. The peptide was initially selected from phage display libraries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af66e198ff01fae6026f48f86424dfbb
https://doi.org/10.1021/acs.molpharmaceut.5b00635
https://doi.org/10.1021/acs.molpharmaceut.5b00635
Publikováno v:
Mol. BioSyst.. 10:128-137
The pleiotropic drug response (PDR) or multidrug resistance (MDR) are cellular defence mechanisms present in all species to deal with potential toxicity from environmental small molecule toxins or bioactives. The rapid induction of MDR by xenobiotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d076d5114577e4230a8d1c720f5f68d
https://doi.org/10.1039/c3mb70351g
https://doi.org/10.1039/c3mb70351g
Publikováno v:
Journal of Immunological Methods. 324:13-25
Recombinant single domain antibody fragments (VHHs) that derive from the unusual camelid heavy chain only IgG class (HCAbs) have many favourable properties compared with single-chain antibodies prepared from conventional IgG. As a result, VHHs have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8f49d65cf9ef2d6fb0d78aba15ef19
https://doi.org/10.1016/j.jim.2007.04.008
https://doi.org/10.1016/j.jim.2007.04.008
Publikováno v:
Molecular bioSystems. 10(7)
Basal ER stress occurs when proteins misfold in normal physiological conditions and are corrected by the unfolded protein response (UPR). Elevated ER stress occurs when misfolding is refractory as found in numerous diseases such as atherosclerosis, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce278e85c5a5ab05de8a6f612bbb1b1c
https://pubmed.ncbi.nlm.nih.gov/24722431
https://pubmed.ncbi.nlm.nih.gov/24722431
Autor:
David R. Maass, Paul H. Atkinson, Peter T. Northcote, Paul H. Teesdale-Spittle, James H. Matthews
Publikováno v:
Zeitschrift fur Naturforschung. C, Journal of biosciences. 68(9-10)
The natural product pateamine A (pateamine) from the sponge Mycale hentscheli is active against a wide range of dividing cells and has been shown to inhibit the functions of the eukaryotic initiation factor 4A (eIF4A). We have identifi ed that pateam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83fd09140483479cbb0e1b5753e0f51
https://pubmed.ncbi.nlm.nih.gov/24459774
https://pubmed.ncbi.nlm.nih.gov/24459774
Autor:
Paul H. Atkinson, David S. Bellows, John H. Miller, Peter T. Northcote, Paul H. Teesdale-Spittle, David R. Maass, Reem Hanna
Publikováno v:
Molecular bioSystems. 10(1)
Baker's yeast, Saccharomyces cerevisiae, has significant sequence conservation with a core subset of mammalian proteins and can serve as a model for disease processes. The aim of this study was to determine whether yeast could be used as a model syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafd838cd6aa4595756ccc526fd3724f
https://pubmed.ncbi.nlm.nih.gov/24161989
https://pubmed.ncbi.nlm.nih.gov/24161989
Autor:
Yee S. Low, David R. Maass, Christina A. Roberts, Cameron Jack, Paul H. Atkinson, Peter W. Bircham, James H. Matthews, Manivannan Yegambaram, Poh Y. Kiew
Publikováno v:
Molecular bioSystems. 7(9)
We developed a procedure for automated confocal microscopy to image the effect of the non-essential yeast gene deletion set on the localisation of the plasma membrane GFP-labelled protein Mrh1p-GFP. To achieve this it was necessary to devise an expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358c8e7895903d313928983bdf6e9a31
https://pubmed.ncbi.nlm.nih.gov/21731954
https://pubmed.ncbi.nlm.nih.gov/21731954
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 5, Iss 9, p e1000597 (2009)
PLoS Pathogens, Vol 5, Iss 9, p e1000597 (2009)
The carbohydrate larval antigen, CarLA, is present on the exposed surface of all strongylid nematode infective L3 larvae tested, and antibodies against CarLA can promote rapid immune rejection of incoming Trichostrongylus colubriformis larvae in shee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7a611b6c5c8d278747628ec6709401
http://europepmc.org/articles/PMC2742895
http://europepmc.org/articles/PMC2742895