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pro vyhledávání: '"David R. Luthin"'
Publikováno v:
Mental Health Clinician. 7:88-94
Introduction:Posttraumatic stress disorder (PTSD) is a common and serious psychiatric illness. Exposure therapy is a type of cognitive behavioral therapy that is considered a first-line treatment option for PTSD. D-cycloserine (DCS) enhances fear ext
Publikováno v:
Journal of Interprofessional Education & Practice. 18:100248
Sports-related concussions are the third leading cause of traumatic brain injuries in student athletes throughout the country. In a survey of all NCAA member institutions, most respondents (92%) indicated that their school had a concussion management
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 35:613-630
Irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) are two common functional gastrointestinal disorders that impair quality of life and pose a significant economic burden to the health care system. Current th
Autor:
David R. Luthin, Terri M Wensel
Publikováno v:
Annals of Pharmacotherapy. 45:1535-1543
Objective: To review the pharmacology, pharmacokinetics, efficacy, and safety of linaclotide for irritable bowel syndrome (IBS). Data Sources: A literature search using PubMed (1966-August 2011) and International Pharmaceutical Abstracts (1970-July 2
Publikováno v:
Currents in Pharmacy Teaching and Learning. 3:171-177
The purpose of this study was to examine pharmacy students' knowledge about, attitudes toward, and intention to provide pharmacy-based immunization services (PBIS). Students enrolled in the third professional year of pharmacy school were surveyed usi
Autor:
Alan P. Jung, David R. Luthin
Publikováno v:
Medicine & Science in Sports & Exercise. 42:355-360
To determine the effect of a high-fat or high-carbohydrate diet and running wheel activity on body composition, body mass, and caloric intake in C57Bl/6 mice.At 4 wk of age, five groups of C57Bl/6 mice were housed individually. Two groups had running
Autor:
Margaret L. Gregory, Eileen Valenzuela Tompkins, Karen D. Nared-Hood, Rosemary Castillo, David R. Luthin, Kenna Anderes, Vazir Haresh N, John M. May, Yufeng Hong, Mary A. Castro, Paderes Genevieve Deguzman, Mark B. Anderson, Eugenia Kraynov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:3635-3639
A novel series of derivatives of mono- and diaminopyrimidines 1 potently displaced binding of a radiolabeled GnRH analogue to human and rat GnRH receptors. Analogues from these series competitively antagonized GnRH-stimulated increases in extracellul
Autor:
Mark B. Anderson, David R. Luthin, Rosemary Castillo, Kenna Anderes, Eugenia A. Iatsimirskaia, John M. May, K. Eric Milgram, Ved P. Pathak, Vazir Haresh N, Margaret L. Gregory, Christie Lance Christopher
Publikováno v:
Pharmaceutical Research. 19:202-208
Purpose. The expression of cytochrome P450 enzymes (CYPs) in animals and humans is under complex hormonal regulation. Chronic treatment with drugs that alter sex hormone levels such as GnRH receptor agonists or antagonists may affect the expression o
Publikováno v:
Biochemical Pharmacology. 51:545-555
An expression plasmid for mammalian cells (CLDN10B) has been modified to add nucleotides encoding hexahistidine and the FLAG peptide (H/F) to cDNAs. The new mammalian expression plasmid has been named pDoubleTrouble (pDT). The plasmid and a recombina
Autor:
David R. Luthin
Publikováno v:
Life sciences. 81(6)
Over the past ten years, tremendous advances in our understanding of the role of the hypothalamic neurohormone, melanin-concentrating hormone (MCH), and its involvement in the regulation of food intake and body weight have been achieved. The MCHR1 re