Zobrazeno 1 - 10
of 181
pro vyhledávání: '"David R. Curtis"'
Autor:
Lance L. Simpson, David R. Curtis
In Volume 1 of this series, attention was focused on neuropoisons of animal origin. In the present volume, attention has been shifted to poisons of plant origin. In both cases, we have attempted to identify those poisons for which there is a large me
Autor:
Per Andersen, David R. Curtis
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 47:159-187
Sir John Eccles, internationally recognized for his remarkable and outstanding impact on the neurosciences for more than six decades, died on 2 May 1997 at the age of 94. He performed his research in Oxford, Sydney, Dunedin, Canberra, Chicago and Buf
Autor:
David R. Curtis, Archibald K. McIntyre
This collection of papers is presented to Sir JOHN ECCLES by his former and present collaborators to commemorate the award of the 1963 Nobel Prize in Medicine, which was shared with A. L. HODGKIN and A. F. HUXLEY. Sir JOHN'S interest in, and influenc
Autor:
David R. Curtis, G. Lacey
Publikováno v:
Experimental Brain Research. 121:319-333
In pentobarbitone-anaesthetised spinal cats, a comparison was made of the effects of intravenous bicuculline hydrochloride, a GABA(A)-receptor antagonist, and several (-)-baclofen (GABA(B)-receptor) antagonists (CGP 35348, 4638 , 56999A) on the prolo
Autor:
David R. Curtis, G Lacey
Publikováno v:
Experimental Brain Research. 114:184-187
In the lumbar ventral horn of pentobarbitone-anaesthetised cats, (-)-baclofen reduces both the synaptic release of excitatory transmitter from muscle group Ia afferent terminations and the duration of the presynaptic action potentials of these termin
Autor:
David R Curtis
Publikováno v:
Journal of Clinical Neuroscience. 10:171-173
Publikováno v:
European Journal of Pharmacology. 264:49-54
In the guinea-pig isolated ileum, both baclofen (5-100 microM) and gamma-aminobutyric acid (GABA; 5-100 microM) induced a bicuculline-insensitive depression of cholinergic twitch contractions which was reversibly and competitively antagonised by 3-am
Autor:
Herdis Fisker, Povl Krogsgaard-Larsen, Jan J. Hansen, Birgitte Nielsen, Bjarke Ebert, David R. Curtis, Ulf Madsen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:107-114
The enantiomers of AMPA and its diethyl derivative were prepared by an enzymatic resolution using α-chymotrypsin in solution. Electrophysiological studies in vivo and in vitro showed the excitatory effects of AMPA to reside mainly in the L-enantiome
Autor:
Torben Bruhn, Nielsen Elsebet Ostergaard, Nils Henrik Diemer, David R. Curtis, Povl Krogsgaard-Larsen, Bjarke Ebert, Ulf Madsen, John Wm. Ferkany, David Beattie, Jørgen S. Johansen
Publikováno v:
ChemInform. 22
The isoxazole amino acid 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl) propionic acid (AMPA) (1), which is a highly selective agonist at the AMPA subtype of excitatory amino acid (EAA) receptors, has been used as a lead for the development of two novel
Autor:
K.-M. Marstokk, David R. Curtis, Knut Maartmann-Moe, Svante Wold, Povl Krogsgaard-Larsen, Harald Møllendal, David Beattie
Publikováno v:
Acta Chemica Scandinavica. 44:18-22