Zobrazeno 1 - 10
of 57
pro vyhledávání: '"David R. Braxton"'
Publikováno v:
Biologics, Vol 3, Iss 3, Pp 198-208 (2023)
Background: Gene fusions occur when two independent genes form a hybrid gene through genomic rearrangements, which often leads to abnormal expression and function of an encoded protein. In hematological and solid cancers, oncogenic fusions may be pro
Externí odkaz:
https://doaj.org/article/e80802faf8c04951ad1a8557ee1444fa
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-6 (2023)
Abstract Background Mifepristone, also known as RU-486, is an anti-progestational steroid with similar chemical structure to anabolic steroids. Given as a single dose in conjunction with misoprostol, mifepristone is used to induce medical abortion. M
Externí odkaz:
https://doaj.org/article/b76b7e50cd3d4eb09fbe0ac436e9e80a
Autor:
Laura Schubert, Andrew Elliott, Anh T. Le, Adriana Estrada-Bernal, Robert C. Doebele, Emil Lou, Hossein Borghaei, Michael J. Demeure, Razelle Kurzrock, Joshua E. Reuss, Sai-Hong Ignatius Ou, David R. Braxton, Christian A. Thomas, Sourat Darabi, Wolfgang Michael Korn, Wafik S. El-Deiry, Stephen V. Liu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeGene fusions involving receptor tyrosine kinases (RTKs) define an important class of genomic alterations with many successful targeted therapies now approved for ALK, ROS1, RET and NTRK gene fusions. Fusions involving the ERBB family of RTKs h
Externí odkaz:
https://doaj.org/article/70a0b6cd821d4f078b9efca4a60b1301
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Complementary and alternative medicine use among Americans is prevalent. Originating in India, Ayurvedic medicine use in the United States has grown 57% since 2002. CAM accounts for a significant proportion of drug induced liver i
Externí odkaz:
https://doaj.org/article/7fdb1e618fcb49e9bcad4714df636f95
Autor:
Sourat Darabi, David R. Braxton, Joanne Xiu, Benedito A. Carneiro, Jeff Swensen, Emmanuel S. Antonarakis, Stephen V. Liu, Rana R. McKay, David Spetzler, Wafik S. El-Deiry, Michael J. Demeure
Publikováno v:
Medicina, Vol 58, Iss 12, p 1818 (2022)
Background: Reversion mutations in BRCA1/2, resulting in restoration of the open reading frame, have been identified as a mechanism of resistance to platinum-based chemotherapy or PARP inhibition. We sought to explore the incidence of BRCA1/2 reversi
Externí odkaz:
https://doaj.org/article/ba50c0656e284a5c8fe58a59c2af572c
Autor:
Shonan Sho, Colin M Court, Stephen Kim, David R Braxton, Shuang Hou, V Raman Muthusamy, Rabindra R Watson, Alireza Sedarat, Hsian-Rong Tseng, James S Tomlinson
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170897 (2017)
Applications of precision oncology strategies rely on accurate tumor genotyping from clinically available specimens. Fine needle aspirations (FNA) are frequently obtained in cancer management and often represent the only source of tumor tissues for p
Externí odkaz:
https://doaj.org/article/f31e17b82b744aacb185b0dfe531dca2
Autor:
David R. Braxton, David B. Bingham, Orly N Farber, Andrew A. Shelton, Nielsen Fernandez-Becker, Christopher Lee, Alexa R Weingarden, Cindy Kin, Gregory J. Scott, Daniel Goff
Publikováno v:
Digestive Diseases and Sciences. 66:413-418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0595192c8d99336018b31968b1fe566d
https://doi.org/10.1007/s10620-020-06425-w
https://doi.org/10.1007/s10620-020-06425-w
Autor:
Bhavana Nayer, Kouichi Hasegawa, Jonathan C. Li, Subhanwita Sakar-Dey, Winita Hardikar, Kevin X. Lau, Karl Trounson, Alison Farley, David R. Braxton, Tatsuhiko Ikeda, Martin F. Pera
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
The Sialyl Lewis A antigen, or CA 19-9, is the prototype serum biomarker for adenocarcinoma of the pancreas. Despite extensive clinical study of CA 19-9 in gastrointestinal malignancies, surprisingly little is known concerning the specific cell types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989b9402c856997acb1a878727611045
http://link.springer.com/article/10.1038/s41598-019-38988-8
http://link.springer.com/article/10.1038/s41598-019-38988-8
Autor:
Sourat Darabi, David R. Braxton, Joanne Xiu, Benedito A. Carneiro, Jeffrey Swensen, Emmanuel S. Antonarakis, Stephen V. Liu, Rana R. McKay, David Spetzler, Wafik S. El-Deiry, Michael J. Demeure
Publikováno v:
Journal of Clinical Oncology. 40:3132-3132
3132 Background: Reversion mutations (RM) in homologous recombination pathway genes including BRCA1/2 have been identified in patients with ovarian, breast, and prostate cancers whose tumors have become refractory to platinum chemotherapy or PARP inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33ba7b9fbd1bbbd6222985784c25514f
https://doi.org/10.1200/jco.2022.40.16_suppl.3132
https://doi.org/10.1200/jco.2022.40.16_suppl.3132
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies
Background Complementary and alternative medicine use among Americans is prevalent. Originating in India, Ayurvedic medicine use in the United States has grown 57% since 2002. CAM accounts for a significant proportion of drug induced liver injury in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d67a47e6042a8bb74699e892bede5b
https://doi.org/10.1186/s12906-021-03251-z
https://doi.org/10.1186/s12906-021-03251-z