Zobrazeno 1 - 10
of 478
pro vyhledávání: '"David R Thomas"'
Autor:
Abderrahman Hachani, Stefano G Giulieri, Romain Guérillot, Calum J Walsh, Marion Herisse, Ye Mon Soe, Sarah L Baines, David R Thomas, Shane Doris Cheung, Ashleigh S Hayes, Ellie Cho, Hayley J Newton, Sacha Pidot, Ruth C Massey, Benjamin P Howden, Timothy P Stinear
Publikováno v:
eLife, Vol 12 (2023)
Staphylococcus aureus infections are associated with high mortality rates. Often considered an extracellular pathogen, S. aureus can persist and replicate within host cells, evading immune responses, and causing host cell death. Classical methods for
Externí odkaz:
https://doaj.org/article/e82ea6004aa84c7a85147fb813e13a3a
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239815 (2020)
IntroductionThere is a dearth of research to guide acute adolescent mental health inpatient care. Self-determination Theory provides evidence that meeting needs for relatedness, autonomy and competence is likely to increase wellbeing and intrinsic mo
Externí odkaz:
https://doaj.org/article/e6803b390278413fa7cf21869e3bca47
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Autophagy is a fundamental and highly conserved eukaryotic process, responsible for maintaining cellular homeostasis and releasing nutrients during times of starvation. An increasingly important function of autophagy is its role in the cell autonomou
Externí odkaz:
https://doaj.org/article/e56af28c13f64520b692bc51c0e9fb7b
Publikováno v:
Pathy's Principles and Practice of Geriatric Medicine. :190-201
Publikováno v:
Mol Microbiol
Anti-bacterial autophagy, known as xenophagy, is a host innate immune response that targets invading pathogens for degradation. Some intracellular bacteria, such as the enteric pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium), utilis
Autor:
Abderrahman Hachani, Stefano G. Giulieri, Romain Guérillot, Calum J. Walsh, Marion Herisse, Ye Mon Soe, Sarah L. Baines, David R. Thomas, Shane Cheung, Ashleigh S. Hayes, Hyun-Jung Cho, Hayley J. Newton, Sacha Pidot, Ruth C. Massey, Benjamin P. Howden, Timothy P. Stinear
Staphylococcus aureusinfections are associated with high mortality rates. Often considered an extracellular pathogen,S. aureuscan persist and replicate within host cells, evading immune responses and causing host cell death. Classical methods for ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cb2c0bc4619dc6d01289c2ba2588fce
https://doi.org/10.1101/2022.12.11.519971
https://doi.org/10.1101/2022.12.11.519971
Autor:
Nichollas E. Scott, David R. Thomas
Publikováno v:
Current Opinion in Structural Biology. 68:18-25
Glycoproteomics is a rapidly growing field which seeks to identify and characterise glycosylation events at a proteome scale. Over the last few years considerable effort has been made in developing new technologies, enrichment systems, and analysis s
Autor:
Claudia Simm, Harshini Weerasinghe, David R. Thomas, Paul F. Harrison, Hayley J. Newton, Traude H. Beilharz, Ana Traven
Publikováno v:
Microbiology Spectrum. 10
Fungal infections are a global threat, but treatments are limited due to a paucity in antifungal drug targets and the emergence of drug-resistant fungi such as Candida auris. Metabolic adaptations enable microbial growth in nutrient-scarce host niche
Autor:
Kaylene J. Simpson, Patrice Newton, Hayley J. Newton, Piyush B. Madhamshettiwar, Shawna C. O. Reed, Nicole Lau, Laura E. Edgington-Mitchell, Craig R. Roy, Sze Ying Ong, Bangyan Xu, Shivani Pasricha, David R. Thomas
Publikováno v:
Proceedings of the National Academy of Sciences. 117:6801-6810
Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-like vacuole through activation of a Dot/Icm-type IVB secretion system and subsequent translocation of effectors that remodel the host cell. Here a genome-wide small interfe