Zobrazeno 1 - 10
of 69
pro vyhledávání: '"David R Stover"'
Autor:
Nandini Rudra-Ganguly, Christine Lowe, Michael Mattie, Mi Sook Chang, Daulet Satpayev, Alla Verlinsky, Zili An, Liping Hu, Peng Yang, Pia Challita-Eid, David R Stover, Daniel S Pereira
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111515 (2014)
Discoidin domain receptor 1 (DDR1) is a member of the receptor tyrosine kinase family. The receptor is activated upon binding to its ligand, collagen, and plays a crucial role in many fundamental processes such as cell differentiation, adhesion, migr
Externí odkaz:
https://doaj.org/article/a2fc346e8a1042a9a41fecea3a3d020b
Autor:
David R. Stover, Dennis Benjamin, Pia Challita-Eid, Ingrid B.J. Joseph, Fernando Doñate, Daniel S. Pereira, Ying Li, Jeffrey Coleman, Steven Duniho, Ruth Moser, Faisal Malik, Claudia Guevara, Hector Aviña, Rossana Nadell, Jimmy Ou, Monica Leavitt, Alla Verlinsky, Linnette Capo, Zili An, Karen Morrison, Kendall Morrison, Arthur Raitano, Michael Mattie
Here, we report the development of an antibody–drug conjugate, ASG-5ME, which targets the solute carrier receptor SLC44A4. SLC44A4 is a member of a family of putative choline transporters that we show to be markedly upregulated in a variety of epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510fb86e62a3f121e464a29893f6e996
https://doi.org/10.1158/1535-7163.c.6538426.v1
https://doi.org/10.1158/1535-7163.c.6538426.v1
Autor:
David R. Stover, John E. Dick, Thomas J. Kipps, Ingrid B.J. Joseph, Fernando Doñate, Pia M. Challita-Eid, Kendall Morrison, Zili An, Michael Y. Choi, Faisal Malik, Sung-Ju Moon, Peng Yang, Joseph D. Abad, Sher Karki, Hector Aviña, Ssucheng J. Hsu, Alla Verlinsky, Nathan Mbong, Liqing Jin, Claudia I. Guevara, Daniel S. Pereira
CD37 is a tetraspanin expressed on malignant B cells. Recently, CD37 has gained interest as a therapeutic target. We developed AGS67E, an antibody–drug conjugate that targets CD37 for the potential treatment of B/T-cell malignancies. It is a fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1527556d255efa3b01de73ceaefa5731
https://doi.org/10.1158/1535-7163.c.6536874.v1
https://doi.org/10.1158/1535-7163.c.6536874.v1
Autor:
David R. Stover, John E. Dick, Thomas J. Kipps, Ingrid B.J. Joseph, Fernando Doñate, Pia M. Challita-Eid, Kendall Morrison, Zili An, Michael Y. Choi, Faisal Malik, Sung-Ju Moon, Peng Yang, Joseph D. Abad, Sher Karki, Hector Aviña, Ssucheng J. Hsu, Alla Verlinsky, Nathan Mbong, Liqing Jin, Claudia I. Guevara, Daniel S. Pereira
Figure S1: AGS67E Binds To B-Cells With High Affinity and Induces Cytotoxicity. Figure S2: AGS67E and AGS67C Internalize Into B Cell Lymphma Cells. Figure S3: AGS67E But Not AGS67C Exhibits Anti-Tumor Activity In MOLM-13 Xenografts. Figure S4: AGS67C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a083c06965c0eadcd1fd9019b5efb71f
https://doi.org/10.1158/1535-7163.22501707
https://doi.org/10.1158/1535-7163.22501707
Autor:
Fernando Doñate, David R. Stover, Sher Karki, Hector Aviña, Lisa Do, Josh Snyder, Veronica Robles, Zhilan Zeng, Karen Morrison, Jimmy Ou, Sathish Kumar Ganesan, Sara Gulesserian, Hui Zhao
Fig. S1. Structure of AGS-16C3F; Figure S2. ENPP3 was not expressed in megakaryocytes; Figure S3. AGS-16C3F did not affect platelet activation; Figure S4. Maturing MKs did not express ENPP3; Figure S5. Fc blocker inhibited FcγRIIA pathway in tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00342acdda45c0ff67ce6d7bb2934973
https://doi.org/10.1158/1535-7163.22509028
https://doi.org/10.1158/1535-7163.22509028
Autor:
David R. Stover, Dennis Benjamin, Pia Challita-Eid, Ingrid B.J. Joseph, Fernando Doñate, Daniel S. Pereira, Ying Li, Jeffrey Coleman, Steven Duniho, Ruth Moser, Faisal Malik, Claudia Guevara, Hector Aviña, Rossana Nadell, Jimmy Ou, Monica Leavitt, Alla Verlinsky, Linnette Capo, Zili An, Karen Morrison, Kendall Morrison, Arthur Raitano, Michael Mattie
Figure S1. Proteolytic release of MMAE from ASG-5ME; Figure S2. SLC44A4 RNA expression in normal and tumor specimens from combined Oncomine data sets; Figure S3: Expression of SLC44A4 in OVCAR-5 cells determined by FACS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed5c9b6bfa05d8cb976b95011b8f210
https://doi.org/10.1158/1535-7163.22506523
https://doi.org/10.1158/1535-7163.22506523
Autor:
David R. Stover, Karen Morrison, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Hector Aviña, Alla Verlinsky, Linnette Capo, Josh T. Snyder, Dawn Ratay Lortie, Wendy Liu, Joseph D. Abad, Peng Yang, Zili An, Arthur Raitano, Pia M. Challita-Eid, Kendall Morrison
SLITRK6 is a member of the SLITRK family of neuronal transmembrane proteins that was discovered as a bladder tumor antigen using suppressive subtractive hybridization. Extensive immunohistochemistry showed SLITRK6 to be expressed in multiple epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c7e29afe45a3470c1c88725becfe7e
https://doi.org/10.1158/1535-7163.c.6537600
https://doi.org/10.1158/1535-7163.c.6537600
Autor:
David R. Stover, Karen Morrison, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Hector Aviña, Alla Verlinsky, Linnette Capo, Josh T. Snyder, Dawn Ratay Lortie, Wendy Liu, Joseph D. Abad, Peng Yang, Zili An, Arthur Raitano, Pia M. Challita-Eid, Kendall Morrison
Details on how the IHC reagent reported in this paper was generated and validated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a45130ccf051fe615d169867a44dd0d
https://doi.org/10.1158/1535-7163.22504038
https://doi.org/10.1158/1535-7163.22504038
Autor:
Fernando Doñate, David R. Stover, Brian A. Mendelsohn, Michael Mattie, Zhilan Zeng, Melissa M. Williams, Mi Sook Chang, James Song, Sathish Kumar Ganesan, Maria Christina Malinao, Sara Gulesserian, Hui Zhao
Figure S1. Chemical structures of MMAF, MMAE and 13C5-MMAE. The asterisks indicate where Carbon-13 isotope has replaced Carbon-12; Figure S2. Expression of CD32 on mature neutrophils. Circulating neutrophils (AllCell) were incubated with anti-CD32 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660456dd4858e9bbebfdffd3e06f96c3
https://doi.org/10.1158/1535-7163.22508311
https://doi.org/10.1158/1535-7163.22508311
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Figure 2. AGS16-7.8 does not inhibit the enzymatic activity of purified ENPP3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059ed3746305bbc2ee01b3af5243dc10
https://doi.org/10.1158/1078-0432.22460382
https://doi.org/10.1158/1078-0432.22460382