Measuring frailty and its association with key outcomes in the ambulance setting: a cross sectional observational study

Autor: Karl Charlton, David R Sinclair, Barbara Hanratty, Emma Burrow, Daniel Stow

Publikováno v: BMC Geriatrics, Vol 22, Iss 1, Pp 1-10 (2022)

Abstract Background Little is known about frailty in the ambulance setting, or its association with outcomes relevant to ambulance services. We sought to measure frailty in people aged ≥ 50 attended by an ambulance, and describe the relationship be

Externí odkaz: https://doaj.org/article/d9cfdee3a77f45568c3075da06a78a1b

High-speed automatic characterization of rare events in flow cytometric data.

Autor: Yuan Qi, Youhan Fang, David R Sinclair, Shangqin Guo, Meritxell Alberich-Jorda, Jun Lu, Daniel G Tenen, Michael G Kharas, Saumyadipta Pyne

Publikováno v: PLoS ONE, Vol 15, Iss 2, p e0228651 (2020)

A new computational framework for FLow cytometric Analysis of Rare Events (FLARE) has been developed specifically for fast and automatic identification of rare cell populations in very large samples generated by platforms like multi-parametric flow c

Externí odkaz: https://doaj.org/article/84362fa455664ae0a5ea0a7fde02aee9

Household wealth, neighbourhood deprivation and frailty amongst middle-aged and older adults in England: a longitudinal analysis over 15 years (2002–2017)

Autor: Asri Maharani, David R Sinclair, Tarani Chandola, Peter Bower, Andrew Clegg, Barbara Hanratty, James Nazroo, Neil Pendleton, Gindo Tampubolon, Chris Todd, Raphael Wittenberg, Terence W O'Neill, Fiona E Matthews

Publikováno v: Age and Ageing. 52

Background frailty is a condition of reduced function and health due to ageing processes and is associated with a higher risk of falls, hospitalisation, disability and mortality. Objective to determine the relationship between household wealth and ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d999b5a90bd0f1a37b5ed878d414a64b
https://doi.org/10.1093/ageing/afad034

Intrathecal Opioid Dosing During Spinal Anesthesia for Cesarean Section: An Integrative Review

Autor: Yuliya Labko, Nicole A. Gonzaga Gomez, David R. Sinclair, Nicole Warren

Publikováno v: Journal of Doctoral Nursing Practice. 13:108-119

Approximately one in three women in the United States deliver via Cesarean section (CS), making it one of the most common surgical procedures in the country. Neuraxial (spinal or epidural) anesthesia is the most effective and common anesthetic approa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98c4929d80f8219a16d04a716bb898b
https://doi.org/10.1891/jdnp-d-19-00025

Can vaccination roll-out be more equitable if population risk is taken into account?

Autor: Asri Maharani, David R. Sinclair, Claire E. Welsh, Daniel Stow, Fiona E. Matthews

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259990 (2021)
Sinclair, D, Maharani, A, Daniel, S, Welsh, C & Matthews, F E 2021, ' Can vaccination roll-out be more equitable if population risk is taken into account? ', PL o S One, vol. 16, no. 11, e0259990, pp. 1-10 . https://doi.org/10.1371/journal.pone.0259990

Background COVID-19 vaccination in many countries, including England, has been prioritised primarily by age. However, people of the same age can have very different health statuses. Frailty is a commonly used metric of health and has been found to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d7ab158fa16099cdf16b541d6f9b78
http://europepmc.org/articles/PMC8592495