Zobrazeno 1 - 10
of 243
pro vyhledávání: '"David R Raleigh"'
Autor:
Hideho Okada, Tiffany Chen, Takahide Nejo, Akane Yamamichi, Shawn L Hervey-Jumper, Su Phyu, Saritha Krishna, Christian Jimenez, Jacob S Young, Senthilnath Lakshmanachetty, Payal Watchmaker, Abrar Choudhury, David R Raleigh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/405fade70dc74da58a13d81a5213fd74
Autor:
Efstathios D Gennatas, Ashley Wu, Steve E Braunstein, Olivier Morin, William C Chen, Stephen T Magill, Chetna Gopinath, Javier E Villaneueva-Meyer, Arie Perry, Michael W McDermott, Timothy D Solberg, Gilmer Valdes, David R Raleigh
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204161 (2018)
BACKGROUND:Meningiomas are stratified according to tumor grade and extent of resection, often in isolation of other clinical variables. Here, we use machine learning (ML) to integrate demographic, clinical, radiographic and pathologic data to develop
Externí odkaz:
https://doaj.org/article/fca87335cdee4d40971bce98ea959213
Autor:
Derrick Lee, Ryan C. Gimple, Xujia Wu, Briana C. Prager, Zhixin Qiu, Qiulian Wu, Vikas Daggubati, Aruljothi Mariappan, Jay Gopalakrishnan, Matthew R. Sarkisian, David R. Raleigh, Jeremy N. Rich
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Glioblastoma ranks among the most aggressive and lethal of all human cancers. Self-renewing, highly tumorigenic glioblastoma stem cells (GSCs) contribute to therapeutic resistance and maintain cellular heterogeneity. Here, we interrogated superenhanc
Externí odkaz:
https://doaj.org/article/9e622da572424f9dad2fb6932cf79adc
Autor:
Jacob S. Young, Reilly L. Kidwell, Allison Zheng, Alex F. Haddad, Manish K. Aghi, David R. Raleigh, Jessica D. Schulte, Nicholas A. Butowski
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Meningiomas are the most common non-metastatic brain tumors, and although the majority are relatively slow-growing and histologically benign, a subset of meningiomas are aggressive and remain challenging to treat. Despite a standard of care that incl
Externí odkaz:
https://doaj.org/article/ce5f3dc4eefb4fa8ab0de859a96b0799
Autor:
Sarah Findakly, Abrar Choudhury, Vikas Daggubati, Melike Pekmezci, Ursula E. Lang, David R. Raleigh
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-7 (2020)
Abstract Meningiomas are the most common primary intracranial tumors, but treatment options for meningioma patients are limited due to incomplete understanding of tumor biology. A small percentage of meningiomas harbor somatic variants in the Hedgeho
Externí odkaz:
https://doaj.org/article/389eadbc308b45a1b90e04e0a7a7e79a
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma
Autor:
S. John Liu, Martina Malatesta, Brian V. Lien, Parna Saha, Shivani S. Thombare, Sung Jun Hong, Leslie Pedraza, Mark Koontz, Kyounghee Seo, Max A. Horlbeck, Daniel He, Harjus S. Birk, Miten Jain, Hugh E. Olsen, Mark Akeson, Jonathan S. Weissman, Michelle Monje, Nalin Gupta, David R. Raleigh, Erik M. Ullian, Daniel A. Lim
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background Long non-coding RNAs (lncRNAs) exhibit highly cell type-specific expression and function, making this class of transcript attractive for targeted cancer therapy. However, the vast majority of lncRNAs have not been tested as potent
Externí odkaz:
https://doaj.org/article/158146c58ea3458da92657b2d5201345
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 2, Pp 233-248 (2020)
Abstract The primary cilium is a cell surface organelle that is an important component of cellular biology. While it was once believed to be a vestigial structure without biologic function, it is now known to have essential roles in critical cellular
Externí odkaz:
https://doaj.org/article/41e05c74cdb7419689fd6bb063711a71
Autor:
Vivian Tang, Rufei Lu, Kanish Mirchia, Jessica Van Ziffle, Patrick Devine, Julieann Lee, Joanna J. Phillips, Arie Perry, David R. Raleigh, Calixto-Hope G. Lucas, David A. Solomon
Publikováno v:
Acta Neuropathologica. 145:497-500
Autor:
Penny K, Sneed, Jason W, Chan, Lijun, Ma, Steve E, Braunstein, Philip V, Theodosopoulos, Shannon E, Fogh, Jean L, Nakamura, Lauren, Boreta, David R, Raleigh, Benjamin P, Ziemer, Olivier, Morin, Shawn L, Hervey-Jumper, Michael W, McDermott
Publikováno v:
Journal of Neurosurgery. 138:104-112
OBJECTIVE The authors previously evaluated risk and time course of adverse radiation effects (AREs) following stereotactic radiosurgery (SRS) for brain metastases, excluding lesions treated after prior SRS. In the present analysis they focus specific
Autor:
Minh P. Nguyen, Ramin A. Morshed, Cecilia L. Dalle Ore, Daniel D. Cummins, Satvir Saggi, William C. Chen, Abrar Choudhury, Akshay Ravi, David R. Raleigh, Stephen T. Magill, Michael W. McDermott, Philip V. Theodosopoulos
Publikováno v:
Journal of Neurosurgery. 138:86-94
OBJECTIVE Meningiomas are the most common primary intracranial tumor, and resection is a mainstay of treatment. It is unclear what duration of imaging follow-up is reasonable for WHO grade I meningiomas undergoing complete resection. This study exami