Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David R Morcock"'
Autor:
Netanya S Utay, Annelys Roque, J Katherina Timmer, David R Morcock, Claire DeLeage, Anoma Somasunderam, Amy C Weintrob, Brian K Agan, Jacob D Estes, Nancy F Crum-Cianflone, Daniel C Douek
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005580 (2016)
People with HIV infection are at increased risk for community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs). Lower CD4 T-cell counts, higher peak HIV RNA levels and epidemiological factors may
Externí odkaz:
https://doaj.org/article/47e17dc096244c13bd0df032bfe2a629
Autor:
Irini Sereti, Jacob D Estes, William L Thompson, David R Morcock, Margaret A Fischl, Thérèse Croughs, Stéphanie Beq, Sylvie Lafaye de Micheaux, Michael D Yao, Alexander Ober, Eleanor M P Wilson, Ven Natarajan, Hiromi Imamichi, Mohamed R Boulassel, Michael M Lederman, Jean-Pierre Routy
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003890 (2014)
Despite antiretroviral therapy (ART), some HIV-infected persons maintain lower than normal CD4(+) T-cell counts in peripheral blood and in the gut mucosa. This incomplete immune restoration is associated with higher levels of immune activation manife
Externí odkaz:
https://doaj.org/article/eb7c83c723e849f4957aae10ad49428d
Autor:
Michael Hull, Jacob D. Estes, Randy Fast, Joshua A. Kramer, Laura Newman, Rodney Wiles, Rebecca Shoemaker, William J. Bosche, Claire Deleage, Christine M. Fennessey, Tyler Malys, James A. Thomas, Charles M. Trubey, Lorna Silipino, Vicky Coalter, Gregory Q. Del Prete, Jeffrey D. Lifson, Cathi Pyle, Duncan Donohue, Adam Wiles, Jacob Kiser, Brandon F. Keele, David R. Morcock, Adrienne E. Swanstrom, Taina T. Immonen, Kelli Oswald, Matthew W. Breed
Publikováno v:
J Clin Invest
The effectiveness of virus-specific strategies, including administered HIV-specific mAbs, to target cells that persistently harbor latent, rebound-competent HIV genomes during combination antiretroviral therapy (cART) has been limited by inefficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b7bbba818f529be5aff422e155c2c2
https://pubmed.ncbi.nlm.nih.gov/33465055
https://pubmed.ncbi.nlm.nih.gov/33465055
Publikováno v:
J Vis Exp
In situ hybridization is a powerful technique to identify specific RNA or DNA sequences within individual cells in tissue sections, providing important insights into physiological processes and disease pathogenesis. In situ hybridization (ISH) has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf00cfab947ed17c74d44c0e88740d2
https://pubmed.ncbi.nlm.nih.gov/32628155
https://pubmed.ncbi.nlm.nih.gov/32628155
Autor:
Sophie Lyons, Marc K. Hellerstein, David R. Morcock, Kara Harvill, Teri Liegler, Sunil K. Joshi, Steven G. Deeks, Ma Somsouk, Hiroyu Hatano, Elizabeth Sinclair, Claire Emson, Peter W. Hunt, Rebecca Hoh, Sharon R Lewin, Steven A. Yukl, Irini Sereti, Ajantha Rhodes, Adam Rupert, Leslie R. Cockerham, Jacob D. Estes
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 3, Pp 310-334 (2017)
Pathogens & immunity, vol 2, iss 3
Pathogens & immunity, vol 2, iss 3
Background: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69aef5a84f03e5ec6a728a3a703506b1
http://paijournal.com/index.php/paijournal/article/view/207
http://paijournal.com/index.php/paijournal/article/view/207
Autor:
Jodi Anderson, Ashley T. Haase, Cavan S. Reilly, Jacob D. Estes, Michael Piatak, Stephen W. Wietgrefe, David R. Morcock, Gregory Q. Del Prete, Katherine Perkey, Timothy W. Schacker, Joseph M. McCune, Xing Pei Hao, Claire Deleage, Jeffrey D. Lifson, Julian W. Bess
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 1, Pp 68-106 (2016)
A primary obstacle to an HIV-1 cure is long-lived viral reservoirs, which must be eliminated or greatly reduced. Cure strategies have largely focused on monitoring changes in T cell reservoirs in peripheral blood (PB), even though the lymphoid tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402f1f078f8c1df979b278307d4039e7
https://paijournal.com/index.php/paijournal/article/view/100
https://paijournal.com/index.php/paijournal/article/view/100
Autor:
Peter D. Burbelo, David R. Morcock, Stig M. R. Jensen, Jacob D. Estes, Virginia Sheikh, Leah Osnos, Ven Natarajan, Stephen B. Kovacs, Joseph W. Adelsberger, Thérèse Croughs, William L. Thompson, Jeffrey S. Bourgeois, Ainhoa Perez-Diez, Jeanette Higgins, Adam Rupert, Irina Maric, JoAnn M. Mican, Alexandra F. Freeman, Irini Sereti, Michael D. Yao, Alice Pau, Gregg Roby, Brian O. Porter, Rebecca DerSimonian
Publikováno v:
Blood. 127:977-988
Idiopathic CD4 lymphopenia (ICL) is a rare syndrome defined by low CD4 T-cell counts (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c4b9f59e6ff94b3a681557bb5fdad5
https://doi.org/10.1182/blood-2015-05-645077
https://doi.org/10.1182/blood-2015-05-645077
Autor:
Christian Suloway, David R. Morcock, Hyun Jung, Yanling Liu, Jack R. Collins, Curtis Lisle, Elijah F. Edmondson, Claire Deleage, Tianyi Miao
Publikováno v:
AIPR
Characterization of collagen deposition in immunostained images is relevant to various pathological conditions, particularly in human immunodeficiency virus (HIV) infection. Accurate segmentation of these collagens and extracting representative featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::485535163fef747a42bb8280b68d6ae0
https://doi.org/10.1109/aipr.2018.8707424
https://doi.org/10.1109/aipr.2018.8707424
Autor:
Romas Geleziunas, Richard Lum, Haesun Park, Vanessa M. Hirsch, Jin Young Bae, Alfred W. Legasse, David R. Morcock, Claire Deleage, Afam A. Okoye, Tonya Swanson, Kenta Matsuda, Rebecca Shoemaker, Louis J. Picker, Michael K. Axthelm, Jeffrey D. Lifson, Carissa Lucero, Yoshinori Fukazawa, Jacob D. Estes, Joseph Hesselgesser, Paul T. Edlefsen, Michael Piatak, Shoko I. Hagen
Publikováno v:
Nature medicine
Chronic-phase HIV and simian immunodeficiency virus (SIV) replication is reduced by as much as 10,000-fold in elite controllers (ECs) compared with typical progressors (TPs), but sufficient viral replication persists in EC tissues to allow viral sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52f0f8d04f7bfad103621242f6ef213
http://europepmc.org/articles/PMC4320022
http://europepmc.org/articles/PMC4320022
Autor:
Vanessa M. Hirsch, Jason M. Brenchley, Alexandra M. Ortiz, Carol L. Vinton, Jacob D. Estes, David R. Morcock, Sonya Whitted, Joseph C. Mudd, Claire Deleage, Nina Calantone
African green monkeys (AGMs) are a natural host of SIV that do not develop simian AIDS. Adult AGMs naturally have low numbers of CD4+ T cells and a large population of MHC class II–restricted CD8αα T cells that are generated through CD4 downregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1129c252875ffd7eaae766bc1c8139
https://europepmc.org/articles/PMC5502537/
https://europepmc.org/articles/PMC5502537/
