Zobrazeno 1 - 10
of 177
pro vyhledávání: '"David R Martinez"'
Autor:
John N Snouwaert, Leigh A Jania, Trang Nguyen, David R Martinez, Alexandra Schäfer, Nicholas J Catanzaro, Kendra L Gully, Ralph S Baric, Mark Heise, Martin T Ferris, Elizabeth Anderson, Katia Pressey, Jacob A Dillard, Sharon Taft-Benz, Victoria K Baxter, Jenny P-Y Ting, Beverly H Koller
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011168 (2023)
Angiotensin-converting enzyme 2 (ACE2), part of the renin-angiotensin system (RAS), serves as an entry point for SARS-CoV-2, leading to viral proliferation in permissive cell types. Using mouse lines in which the Ace2 locus has been humanized by synt
Externí odkaz:
https://doaj.org/article/75be0b479d294111a5b725cdfbedb42c
Autor:
Amit Kumar, Elena E Giorgi, Joshua J Tu, David R Martinez, Joshua Eudailey, Michael Mengual, Manukumar Honnayakanahalli Marichannegowda, Russell Van Dyke, Feng Gao, Sallie R Permar
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009478 (2021)
Despite considerable reduction of mother-to-child transmission (MTCT) of HIV through use of maternal and infant antiretroviral therapy (ART), over 150,000 infants continue to become infected with HIV annually, falling far short of the World Health Or
Externí odkaz:
https://doaj.org/article/9175324066cc4e44ade847ce15b4fe63
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008303 (2020)
Externí odkaz:
https://doaj.org/article/6de557a196e04b20af51a00282f5bf67
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007161 (2018)
Externí odkaz:
https://doaj.org/article/92034064d84e45259d09105d207d48da
Autor:
Amit Kumar, Claire E P Smith, Elena E Giorgi, Joshua Eudailey, David R Martinez, Karina Yusim, Ayooluwa O Douglas, Lisa Stamper, Erin McGuire, Celia C LaBranche, David C Montefiori, Genevieve G Fouda, Feng Gao, Sallie R Permar
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006944 (2018)
Despite extensive genetic diversity of HIV-1 in chronic infection, a single or few maternal virus variants become the founders of an infant's infection. These transmitted/founder (T/F) variants are of particular interest, as a maternal or infant HIV
Externí odkaz:
https://doaj.org/article/1e3c487738a1442f80d4b880441b3f66
Autor:
Lautaro G Perez, David R Martinez, Allan C deCamp, Abraham Pinter, Phillip W Berman, Donald Francis, Faruk Sinangil, Carter Lee, Kelli Greene, Hongmei Gao, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Jaranit Kaewkungwal, Punnee Pitisuttithum, James Tartaglia, Robert J O'Connell, Merlin L Robb, Nelson L Michael, Jerome H Kim, Peter Gilbert, David C Montefiori
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180720 (2017)
Non-neutralizing IgG to the V1V2 loop of HIV-1 gp120 correlates with a decreased risk of HIV-1 infection but the mechanism of protection remains unknown. This V1V2 IgG correlate was identified in RV144 Thai trial vaccine recipients, who were primed w
Externí odkaz:
https://doaj.org/article/c36ea6f861184e5d9675e59626f76437
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1005997 (2016)
Externí odkaz:
https://doaj.org/article/bfc81de8a87444aea5a8a8e201f2dd4e
Autor:
David R. Martinez, Alexandra Schaefer, Tyler D. Gavitt, Michael L. Mallory, Esther Lee, Nicholas J. Catanzaro, Haiyan Chen, Kendra Gully, Trevor Scobey, Pooja Korategere, Alecia Brown, Lena Smith, Rob Parks, Maggie Barr, Amanda Newman, Cindy Bowman, John M. Powers, Katayoun Mansouri, Robert J. Edwards, Ralph S. Baric, Barton F. Haynes, Kevin O. Saunders
Publikováno v:
bioRxiv
SUMMARYThe emergence of three distinct highly pathogenic human coronaviruses – SARS-CoV in 2003, MERS-CoV in 2012, and SARS-CoV-2 in 2019 – underlines the need to develop broadly active vaccines against theMerbecovirusandSarbecovirusbetacoronavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b315c72e80a8eb03736cfa6d7adabb
https://doi.org/10.1101/2023.05.22.540829
https://doi.org/10.1101/2023.05.22.540829
Publikováno v:
Science Immunology. 8
Delivery of mRNAs encoding influenza HA antigens covering all known subtypes and lineages elicits cross-reactive and protective immunity.
Autor:
Anthony L. Cook, Xuan He, Jake Yalley-Ogunro, Ralph S. Baric, Stefan O. Mueller, David R. Martinez, Jinyan Liu, Andrew C. Cole, Tori Giffin, Hanne Leth Andersen, Daniel Valentin, Benjamin Petsch, Katherine McMahan, Dan H. Barouch, Noe B. Mercado, Shivani A. Patel, Laurent Pessaint, Renita Brown, Jeanne Muench, Julia Barrett, David L. Hope, Adrianus C. M. Boon, Mark G. Lewis, Abishek Chandrashekar, Owen Sanborn, Makda S. Gebre, Zack Flinchbaugh, Xiaowen Liu, Susanne Rauch, Elyse Teow, Daniel Sellers, Amanda J. Martinot, Nicole Roth, Jingyou Yu
Publikováno v:
Nature
The CVnCoV (CureVac) mRNA vaccine for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was recently evaluated in a phase 2b/3 efficacy trial in humans1. CV2CoV is a second-generation mRNA vaccine containing non-modified nucleosides but wi