Zobrazeno 1 - 10
of 281
pro vyhledávání: '"David R Hill"'
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0280979 (2023)
Emerging infection diseases (EIDs) are an increasing threat to global public health, especially when the disease is newly emerging. Institutions of higher education (IHEs) are particularly vulnerable to EIDs because student populations frequently sha
Externí odkaz:
https://doaj.org/article/e38ff17741bd471baf8aa78edeb7e21b
Autor:
Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Brooke Bons, Courtney Fields, Gautam J Sule, Jason S Knight, Christiane E Wobus, Jason R Spence, Vincent B Young, Mary X O'Riordan, Basel H Abuaita
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010855 (2022)
Infection of the human gut by Salmonella enterica Typhimurium (STM) results in a localized inflammatory disease that is not mimicked in murine infections. To determine mechanisms by which neutrophils, as early responders to bacterial challenge, direc
Externí odkaz:
https://doaj.org/article/bc7475739de7493a804ae366c621795c
Autor:
Basel H Abuaita, Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Brooke Bons, Courtney Fields, Christiane E Wobus, Jason R Spence, Vincent B Young, Mary X O'Riordan
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009987 (2021)
Salmonella enterica represents over 2500 serovars associated with a wide-ranging spectrum of disease; from self-limiting gastroenteritis to invasive infections caused by non-typhoidal serovars (NTS) and typhoidal serovars, respectively. Host factors
Externí odkaz:
https://doaj.org/article/dd451e9f855f4a058b08f270822eb9ab
Autor:
Abimbola O Kolawole, Carmen Mirabelli, David R Hill, Sophia A Svoboda, Andrew B Janowski, Karla D Passalacqua, Benancio N Rodriguez, Michael K Dame, Pamela Freiden, Ryan P Berger, Diem-Lan Vu, Myra Hosmillo, Mary X D O'Riordan, Stacey Schultz-Cherry, Susana Guix, Jason R Spence, David Wang, Christiane E Wobus
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008057 (2019)
Human astroviruses (HAstV) are understudied positive-strand RNA viruses that cause gastroenteritis mostly in children and the elderly. Three clades of astroviruses, classic, MLB-type and VA-type have been reported in humans. One limitation towards a
Externí odkaz:
https://doaj.org/article/4e54391aa6234d259c5d407004f26f1d
Autor:
David R Hill, Sha Huang, Melinda S Nagy, Veda K Yadagiri, Courtney Fields, Dishari Mukherjee, Brooke Bons, Priya H Dedhia, Alana M Chin, Yu-Hwai Tsai, Shrikar Thodla, Thomas M Schmidt, Seth Walk, Vincent B Young, Jason R Spence
Publikováno v:
eLife, Vol 6 (2017)
The human gastrointestinal tract is immature at birth, yet must adapt to dramatic changes such as oral nutrition and microbial colonization. The confluence of these factors can lead to severe inflammatory disease in premature infants; however, invest
Externí odkaz:
https://doaj.org/article/4f3e225ce6c5433682f7583fb2e61dd3
Autor:
David R Hill, Roberto Cieza, Veda K. Yadagiri, Phillip Tarr, Jason R. Spence, Vincent B. Young
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 13-13 (2019)
OBJECTIVES/SPECIFIC AIMS: The central goal of this proposal is to characterize the mechanisms that mediate success or failure of immature intestinal barrier in necrotizing enterocilitis. METHODS/STUDY POPULATION: To do this, I will utilize stem cell
Externí odkaz:
https://doaj.org/article/a1962632a7864a27929b1f366a2c2272
Autor:
Briana R Dye, David R Hill, Michael AH Ferguson, Yu-Hwai Tsai, Melinda S Nagy, Rachel Dyal, James M Wells, Christopher N Mayhew, Roy Nattiv, Ophir D Klein, Eric S White, Gail H Deutsch, Jason R Spence
Publikováno v:
eLife, Vol 4 (2015)
Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human development and disease. Here, we report the step-wise differentiation of human pluripotent ste
Externí odkaz:
https://doaj.org/article/624cb8811bd0435ea1035b2a49bdcdf7
Autor:
David R. Hill, Rachael H. Buck
Publikováno v:
Nutrients; Volume 15; Issue 10; Pages: 2339
Human milk represents an optimal source of nutrition during infancy. Milk also serves as a vehicle for the transfer of growth factors, commensal microbes, and prebiotic compounds to the immature gastrointestinal tract. These immunomodulatory and preb
Autor:
Chhinder P. Sodhi, Raheel Ahmad, William B. Fulton, Carla Lopez, Benjamin Eke, Daniel Scheese, Johannes Duess, Steven Steinway, Zachariah Raouf, Hannah Moore, Koichi Tsuboi, Maame Sampah, Hee-Seong Jang, Rachael H. Buck, David R. Hill, Grace M. Niemiro, Thomas Prindle, Sanxia Wang, Meghan Wang, Hongpeng Jia, Jonathan Catazaro, Peng Lu, David J. Hackam
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology.
Necrotizing enterocolitis (NEC) is the leading cause of morbidity and mortality in premature infants. One of the most devastating complications of NEC is the development of NEC-induced brain injury, which manifests as impaired cognition that persists
Autor:
Xinyang Li, Yingyi Mao, Shuang Liu, Jin Wang, Xiang Li, Yanrong Zhao, David R. Hill, Shuo Wang
Publikováno v:
Nutrients; Volume 14; Issue 19; Pages: 4131
Background: Human milk oligosaccharides (HMOs) are a group of breast milk carbohydrates exerting pivotal benefits for breastfed infants. Whether maternal diet is associated with breastmilk HMO composition has not been well-characterized. Objectives: