Zobrazeno 1 - 10
of 892
pro vyhledávání: '"David R Brown"'
Autor:
Javier A Tamargo, Haley R Martin, Janet Diaz-Martinez, Ivan Delgado-Enciso, Angelique Johnson, Jose A Bastida Rodriguez, Mary Jo Trepka, David R Brown, Nana A Garba, Eneida O Roldan, Yolangel Hernandez Suarez, Aileen M Marty, Zoran Bursac, Adriana Campa, Marianna K Baum
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297327 (2024)
The Coronavirus Disease 2019 (COVID-19) pandemic has disproportionately impacted people who use drugs (PWUD). This study explored relationships between drug use, COVID-19 testing, vaccination, and infection. This cross-sectional study was conducted i
Externí odkaz:
https://doaj.org/article/dfc6c8bf0d3549729d4b87be73aa1bd3
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237325 (2020)
Recent research has shown relationships between health outcomes and residence proximity to unconventional oil and natural gas development (UOGD). The challenge of connecting health outcomes to environmental stressors requires ongoing research with ne
Externí odkaz:
https://doaj.org/article/f55b5812b20042d49683952eaac21ab8
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202462 (2018)
Emerging evidence indicates that proximity to unconventional oil and gas development (UOGD) is associated with health outcomes. There is intense debate about "How close is too close?" for maintaining public health and safety. The goal of this Delphi
Externí odkaz:
https://doaj.org/article/b42d47e966864c4991cdaa4979eb994d
Autor:
Mark Lyte, David R Brown
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191037 (2018)
The ability of prokaryotic microbes to produce and respond to neurochemicals that are more often associated with eukaryotic systems is increasingly recognized through the concept of microbial endocrinology. Most studies have described the phenomena o
Externí odkaz:
https://doaj.org/article/9cfd076124bc4365b9cbd701d1949832
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171925 (2017)
α-Synuclein misfolding and aggregation is often accompanied by β-amyloid deposition in some neurodegenerative diseases. We hypothesised that α-synuclein promotes β-amyloid production from APP. β-Amyloid levels and APP amyloidogenic processing we
Externí odkaz:
https://doaj.org/article/a521125127db4c19b5e00e42d0494224
Autor:
David R Brown
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 3, Pp 534-543 (2004)
The prion protein (PrPc) is a glycoprotein that is not only expressed predominantly by neurones but also by other cells, including astrocytes. The recent identification of PrPc as a Cu-binding protein has opened the way to investigating its function
Externí odkaz:
https://doaj.org/article/a68e455867814785be32553ed7530af8
Autor:
Keifer P Walsh, Laurie S Minamide, Sarah J Kane, Alisa E Shaw, David R Brown, Bruce Pulford, Mark D Zabel, J David Lambeth, Thomas B Kuhn, James R Bamburg
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95995 (2014)
Neurites of neurons under acute or chronic stress form bundles of filaments (rods) containing 1∶1 cofilin∶actin, which impair transport and synaptic function. Rods contain disulfide cross-linked cofilin and are induced by treatments resulting in
Externí odkaz:
https://doaj.org/article/a3df7ff5157a402b8837a2ab94fa9b44
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15814 (2011)
α-synuclein (αS) is a cellular protein mostly known for the association of its aggregated forms with a variety of diseases that include Parkinson's disease and Dementia with Lewy Bodies. While the role of αS in disease is well documented there is
Externí odkaz:
https://doaj.org/article/30007aa664934eea8a1559e5b3ddc08a
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17354 (2011)
The progression of many human neurodegenerative disorders is associated with an accumulation of alpha-synuclein. Alpha-synuclein belongs to the homologous synuclein family, which includes beta-synuclein. It has been proposed that beta-synuclein may b
Externí odkaz:
https://doaj.org/article/bca48ad02fd8418692e4f186a792b5ff
Autor:
Paul Davies, David R Brown
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7518 (2009)
Prion diseases are considered to be transmissible. The existence of sporadic forms of prion diseases such as scrapie implies an environmental source for the infectious agent. This would suggest that under certain conditions the prion protein, the acc
Externí odkaz:
https://doaj.org/article/6b55cc0fef3f481ea5fdbff936bd2582