Zobrazeno 1 - 10
of 748
pro vyhledávání: '"David R Boulware"'
Autor:
Preethiya Sekar, Gila Hale, Jane Gakuru, David B. Meya, David R. Boulware, Jayne Ellis, Elizabeth Nalintya, Nathan C. Bahr, Radha Rajasingham
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 8, Pp 1523-1530 (2024)
Histoplasmosis is a fungal disease associated with substantial mortality rates among persons with advanced HIV disease. Our systematic review synthesized data on the global prevalence of Histoplasma-caused antigenuria in persons with HIV. We search
Externí odkaz:
https://doaj.org/article/e2015f7459c0437385a24fb430e929a5
Autor:
Abigail R. Gress, Christine E. Ronayne, Joshua M. Thiede, David K. Meyerholz, Samuel Okurut, Julia Stumpf, Tailor V. Mathes, Kenneth Ssebambulidde, David B. Meya, Fiona V. Cresswell, David R. Boulware, Tyler D. Bold
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract After Mycobacterium tuberculosis (Mtb) infection, many effector T cells traffic to the lungs, but few become activated. Here we use an antigen receptor reporter mouse (Nur77-GFP) to identify recently activated CD4 T cells in the lungs. These
Externí odkaz:
https://doaj.org/article/ca259876e3be47d9b437b62b4a3c7cd7
Publikováno v:
Therapeutic Advances in Urology, Vol 16 (2024)
Background: Stress urinary incontinence (SUI) presents as unintentional urine leakage associated with activities. It significantly affects quality of life (QoL) and is the most common type of incontinence in women. Current treatment options, particul
Externí odkaz:
https://doaj.org/article/7b14ac84aa904eb2b980710ab387373e
Autor:
Matthew W. McCarthy, Christopher J. Lindsell, Radha Rajasingham, Thomas G. Stewart, David R. Boulware, Susanna Naggie
Publikováno v:
Journal of Clinical and Translational Science, Vol 8 (2024)
Externí odkaz:
https://doaj.org/article/00e5bfe7258340a9982bb8f33607360b
Autor:
Samuel Okurut, David R. Boulware, Elizabeth Okafor, Joshua Rhein, Henry Kajumbula, Bernard S. Bagaya, Freddie Bwanga, Joseph O. Olobo, Yukari C. Manabe, David B. Meya, Edward N. Janoff
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSurvival among people with HIV-associated cryptococcal meningitis (CM) remains low, particularly among women, despite the currently optimal use of antifungal drugs. Cryptococcus dissemination into the central nervous system [brain, spinal
Externí odkaz:
https://doaj.org/article/85c7253969b7452594bd58c0ae40b479
Autor:
Oriol Mitjà, Gilmar Reis, David R. Boulware, Adam M. Spivak, Ammar Sarwar, Christine Johnston, Brandon Webb, Michael D. Hill, Davey Smith, Peter Kremsner, Marla Curran, David Carter, Jim Alexander, Marc Corbacho, Todd C. Lee, Katherine Huppler Hullsiek, Emily G. McDonald, Rachel Hess, Michael Hughes, Jared M. Baeten, Ilan Schwartz, Luanne Metz, Lawrence Richer, Kara W. Chew, Eric Daar, David Wohl, Michael Dunne
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 3, Pp 524-535 (2023)
Abstract Hydroxychloroquine (HCQ) was initially promoted as an oral therapy for early treatment of coronavirus disease 2019 (COVID‐19). Conventional meta‐analyses cannot fully address the heterogeneity of different designs and outcomes of randomi
Externí odkaz:
https://doaj.org/article/2f0332ecf5a2428ebd4d3c3b0d83894f
Autor:
Caleb P. Skipper, Katherine Huppler Hullsiek, Fiona V. Cresswell, Kiiza K. Tadeo, Michael Okirwoth, Mark Blackstad, Nelmary Hernandez-Alvarado, Claudia Fernández-Alarcón, Stewart Walukaga, Emily Martyn, Jayne Ellis, Kenneth Ssebambulidde, Lillian Tugume, Edwin Nuwagira, Joshua Rhein, David B. Meya, David R. Boulware, Mark R. Schleiss
Publikováno v:
International Journal of Infectious Diseases, Vol 122, Iss , Pp 785-792 (2022)
Objectives: CMV viremia is associated with increased mortality in persons with HIV. We previously demonstrated that CMV viremia was a risk factor for 10-week mortality in antiretroviral therapy (ART)-naïve persons with cryptococcal meningitis. We in
Externí odkaz:
https://doaj.org/article/b0a922ef9fe944e9a2f7fe858d771042
Autor:
Adrian F Hernandez, David R Boulware, Radha Rajasingham, Christopher W Woods, Kevin J Anstrom, Ravi Amaravadi, Benjamin S Abella, Hwanhee Hong, Anne Friedland, Mengyi Hu, Susan Halabi, John E McKinnon, Jorge Rojas-Serrano, Angélica Margarita Portillo-Vázquez, Susanna Naggie
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Objective We studied the safety and efficacy of hydroxychloroquine (HCQ) as pre-exposure prophylaxis for COVID-19 in healthcare workers (HCWs), using a meta-analysis of randomised controlled trials (RCTs).Data sources PubMed and EMBASE databases were
Externí odkaz:
https://doaj.org/article/10d79c6e96d6445e963962280b7084b7
Autor:
José E. Vidal, Fernanda Gurgel Oliveira, Marcela Vieira, Luisa Pereira, Rodovaldo M. Lucas Junior, Bruno Fukelman Guedes, Marcello Chaves Magri, David R. Boulware
Publikováno v:
Journal of Fungi, Vol 9, Iss 12, p 1140 (2023)
Cryptococcosis in HIV-negative patients can be an opportunistic or endemic disease. There are no published studies on the use of the finger-prick whole blood (point-of-care) cryptococcal antigen lateral flow assay (CrAg LFA) for diagnosing cryptococc
Externí odkaz:
https://doaj.org/article/cf3aef43d63b4860a91eec744ad313d6
Autor:
Tafese Beyene Tufa, Hans Martin Orth, Tobias Wienemann, Bjoern-Erik Ole Jensen, Colin R. Mackenzie, David R. Boulware, Tom Luedde, Torsten Feldt
Publikováno v:
Journal of Fungi, Vol 9, Iss 8, p 836 (2023)
Cryptococcosis is the leading cause of death among people with HIV in Sub-Saharan Africa. The lack of optimum diagnoses and medications significantly impair the management of the disease. We investigated the burden of cryptococcosis and related morta
Externí odkaz:
https://doaj.org/article/f2c4f9e9fb884f199efd35d2347fa4fa